Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   GPA00_RS02590 Genome accession   NZ_CP046629
Coordinates   526067..527326 (-) Length   419 a.a.
NCBI ID   WP_157327439.1    Uniprot ID   -
Organism   Streptococcus equinus strain CNU G6     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 521067..532326
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPA00_RS02560 (GPA00_02560) - 521154..522731 (-) 1578 WP_157327437.1 DUF2079 domain-containing protein -
  GPA00_RS09865 - 522774..522902 (-) 129 WP_021143294.1 hypothetical protein -
  GPA00_RS02565 (GPA00_02565) - 523001..523318 (-) 318 WP_006531413.1 DUF1292 domain-containing protein -
  GPA00_RS02570 (GPA00_02570) ruvX 523351..523770 (-) 420 WP_004233508.1 Holliday junction resolvase RuvX -
  GPA00_RS02575 (GPA00_02575) - 523767..524036 (-) 270 WP_004233510.1 IreB family regulatory phosphoprotein -
  GPA00_RS02580 (GPA00_02580) spx 524267..524665 (-) 399 WP_004233512.1 transcriptional regulator Spx -
  GPA00_RS02585 (GPA00_02585) recA 524863..526017 (-) 1155 WP_004233517.1 recombinase RecA Machinery gene
  GPA00_RS02590 (GPA00_02590) cinA 526067..527326 (-) 1260 WP_157327439.1 competence/damage-inducible protein A Machinery gene
  GPA00_RS02595 (GPA00_02595) - 527440..528552 (-) 1113 WP_232524226.1 MFS transporter -
  GPA00_RS02600 (GPA00_02600) - 528765..529322 (-) 558 WP_198362632.1 DNA-3-methyladenine glycosylase I -
  GPA00_RS02605 (GPA00_02605) ruvA 529352..529945 (-) 594 WP_024344431.1 Holliday junction branch migration protein RuvA -
  GPA00_RS02610 (GPA00_02610) mutL 529946..531889 (-) 1944 WP_157327446.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 45591.06 Da        Isoelectric Point: 4.9810

>NTDB_id=406284 GPA00_RS02590 WP_157327439.1 526067..527326(-) (cinA) [Streptococcus equinus strain CNU G6]
MKAEIIAVGTEILTGQITNTNAQFLSEEFAKLGIDVFFQTAVGDNEERLLSIIALASKRSDLVVLCGGLGPTEDDLTKQT
LAKYLGRNLVFDEQASKRLDEFFATRPQFTRTANNERQAQLIEGATPLQNSTGLAVGGVLEVDGVTYVVLPGPPSELKPM
VWDYLVPLLSSDHKQLYSRVLRFFGIGESQLVTVLSDLIENQTDPTIAPYAKTGEVTLRLSTKADDLETAKAKLDELEHK
ILAKKTLNSIPLENLLYGYGDDNSMARVVFDLLKQKHKTITAAESLTAGLFQSSIADFPGSSAVFNGGFVTYSIEEKAKM
LQIPLKDLQEHGVVSHFTAEKMAEQSRLLTDADFGIGLTGVAGPDGLEGHPAGTVFIGIATREKVHSIRVVIGGRSRSDV
RCIACLYAFNLVRQALLQD

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=406284 GPA00_RS02590 WP_157327439.1 526067..527326(-) (cinA) [Streptococcus equinus strain CNU G6]
ATGAAAGCTGAAATCATTGCTGTTGGAACAGAGATTTTAACAGGACAAATCACAAATACAAATGCACAATTTCTATCAGA
GGAATTTGCTAAGTTAGGGATTGATGTCTTTTTCCAAACGGCAGTTGGGGACAATGAAGAACGTCTGCTGTCTATCATTG
CTTTGGCAAGTAAGCGCAGTGATTTAGTTGTTCTTTGCGGTGGTTTAGGACCAACCGAAGATGATTTAACAAAACAAACT
TTGGCAAAATATCTAGGACGTAACTTGGTTTTTGATGAACAGGCAAGTAAACGTTTGGATGAATTCTTTGCGACACGTCC
GCAATTTACAAGAACAGCTAACAATGAACGTCAGGCTCAATTGATTGAGGGGGCAACACCTCTTCAAAATAGTACGGGAC
TTGCTGTAGGTGGTGTTCTGGAAGTCGATGGTGTTACTTATGTCGTTCTTCCTGGACCACCAAGTGAATTGAAGCCTATG
GTTTGGGACTATTTAGTGCCATTGCTATCTAGTGACCACAAGCAATTGTATTCACGTGTCTTACGTTTCTTTGGTATCGG
GGAAAGTCAGTTGGTAACTGTTTTGTCAGATTTGATTGAAAATCAAACAGACCCAACAATCGCTCCGTATGCCAAAACAG
GTGAAGTGACACTTAGATTGTCAACGAAGGCTGATGACCTTGAAACAGCTAAGGCTAAGTTGGATGAGCTTGAGCATAAG
ATTCTTGCTAAGAAGACTTTAAATAGTATTCCGCTTGAAAATTTGCTTTATGGATACGGTGATGATAATAGTATGGCGCG
TGTTGTTTTTGATTTACTTAAGCAAAAACATAAGACTATTACGGCTGCAGAAAGTTTGACAGCTGGTTTGTTTCAATCAA
GTATTGCTGATTTTCCAGGCTCTTCAGCAGTTTTTAATGGTGGTTTTGTGACTTATAGCATTGAAGAAAAGGCAAAAATG
CTTCAAATTCCTTTAAAAGATTTACAAGAACATGGGGTTGTGAGTCATTTTACAGCTGAAAAAATGGCTGAGCAGTCACG
ATTGCTGACAGACGCTGATTTTGGAATTGGCTTAACAGGAGTTGCTGGTCCAGATGGTCTAGAAGGTCATCCAGCGGGAA
CAGTTTTCATAGGTATTGCTACAAGAGAAAAAGTTCATTCTATCCGTGTTGTTATAGGTGGACGAAGCCGCTCAGATGTG
CGTTGTATTGCATGTTTGTATGCTTTTAACTTAGTACGTCAAGCTTTATTACAAGACTAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(263-415)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

71.942

99.523

0.716
  cinA Streptococcus mitis SK321

71.36

100

0.714
  cinA Streptococcus mitis NCTC 12261

70.644

100

0.706
  cinA Streptococcus pneumoniae Rx1

69.451

100

0.695
  cinA Streptococcus pneumoniae TIGR4

69.451

100

0.695
  cinA Streptococcus pneumoniae R6

69.451

100

0.695
  cinA Streptococcus pneumoniae D39

69.212

100

0.692
  cinA Streptococcus suis isolate S10

53.606

99.284

0.532
  cinA Bacillus subtilis subsp. subtilis str. 168

45.024

100

0.453

Multiple sequence alignment