Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/comE2   Type   Regulator
Locus tag   GO596_RS04015 Genome accession   NZ_CP046628
Coordinates   799862..800590 (+) Length   242 a.a.
NCBI ID   WP_074628324.1    Uniprot ID   -
Organism   Streptococcus equinus strain CNU 77-23     
Function   activate transcription of early competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 794862..805590
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GO596_RS04000 (GO596_04000) comD/comD3 795094..796467 (+) 1374 WP_157339242.1 GHKL domain-containing protein Regulator
  GO596_RS04005 (GO596_04005) comD/comD3 796840..797853 (+) 1014 WP_232516875.1 sensor histidine kinase Regulator
  GO596_RS04010 (GO596_04010) comD/comD3 797850..799241 (+) 1392 WP_157339244.1 GHKL domain-containing protein Regulator
  GO596_RS04015 (GO596_04015) comE/comE2 799862..800590 (+) 729 WP_074628324.1 LytR/AlgR family response regulator transcription factor Regulator
  GO596_RS04025 (GO596_04025) rsgA 800882..801754 (+) 873 WP_157339245.1 ribosome small subunit-dependent GTPase A -
  GO596_RS04030 (GO596_04030) rpe 801761..802423 (+) 663 WP_157339246.1 ribulose-phosphate 3-epimerase -
  GO596_RS04035 (GO596_04035) - 802416..803048 (+) 633 WP_157339247.1 thiamine diphosphokinase -
  GO596_RS04040 (GO596_04040) rmuC 803111..804325 (+) 1215 WP_371851905.1 DNA recombination protein RmuC -
  GO596_RS04045 (GO596_04045) - 804315..805256 (+) 942 WP_024343528.1 3'-5' exoribonuclease YhaM family protein -

Sequence

Protein


Download         Length: 242 a.a.        Molecular weight: 28313.55 Da        Isoelectric Point: 6.4962

>NTDB_id=406243 GO596_RS04015 WP_074628324.1 799862..800590(+) (comE/comE2) [Streptococcus equinus strain CNU 77-23]
MIDIYVLEDNVNQQFRIERMIDELLDENQWDYRHFEIFSEPSHFLNFVEESCPQIFFLDIDINGDNKKGIEVAKKIREKS
RTATIVFVTTHSEFMLLTYRAQVSALDFIDKSDEDSSIKINLKNCLRKVIENQALTMPQEFFVFENNKATIRIPMDEILY
FETAESHRLKLVTKSGQRNFYGSIKEVMAANQTFFRSHKSYLINLDNVVCLDKKNSLVHFVGGQSCLVSKKYIKELKLKI
GV

Nucleotide


Download         Length: 729 bp        

>NTDB_id=406243 GO596_RS04015 WP_074628324.1 799862..800590(+) (comE/comE2) [Streptococcus equinus strain CNU 77-23]
ATGATTGACATCTATGTATTGGAGGACAATGTAAATCAGCAATTTCGGATTGAAAGGATGATTGATGAACTACTCGACGA
AAATCAGTGGGACTATCGTCATTTTGAAATATTTAGTGAGCCGTCTCATTTTCTAAATTTTGTTGAGGAATCTTGCCCAC
AAATTTTTTTCTTAGATATTGATATCAATGGTGATAATAAAAAGGGAATTGAAGTCGCTAAGAAAATTAGGGAGAAATCT
AGAACAGCTACGATTGTTTTTGTTACGACGCATTCTGAGTTTATGTTGTTGACTTACCGAGCACAGGTTAGTGCACTTGA
TTTTATTGATAAGTCAGATGAAGACAGTTCGATAAAAATTAATTTAAAAAATTGTTTACGAAAGGTCATCGAAAATCAGG
CTCTTACGATGCCACAGGAATTTTTTGTATTTGAAAATAATAAAGCTACTATTCGTATTCCGATGGATGAAATTCTTTAT
TTTGAAACAGCTGAAAGTCATCGACTGAAGTTGGTTACAAAGTCGGGACAACGTAATTTTTATGGTTCAATCAAAGAAGT
AATGGCTGCTAATCAGACCTTTTTTAGAAGCCACAAATCATATCTGATTAATCTTGATAATGTTGTGTGCTTAGATAAAA
AGAATAGTTTGGTGCATTTTGTCGGTGGTCAATCTTGCCTTGTTTCAAAGAAATACATTAAAGAATTAAAGTTGAAAATA
GGTGTTTAG

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(149-239)

Response regulator receiver domain (Response_reg)

(6-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/comE2 Streptococcus equinus JB1

74.167

99.174

0.736
  comE/comE1 Streptococcus equinus JB1

44.118

98.347

0.434
  comE/blpR Streptococcus mutans UA159

40.164

100

0.405
  comE/comE2 Streptococcus gordonii strain NCTC7865

38.367

100

0.388
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

38.367

100

0.388

Multiple sequence alignment