Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD   Type   Regulator
Locus tag   GOM46_RS08295 Genome accession   NZ_CP046525
Coordinates   1703196..1704515 (-) Length   439 a.a.
NCBI ID   WP_235083586.1    Uniprot ID   -
Organism   Streptococcus infantis strain SO     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1698196..1709515
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM46_RS08270 (GOM46_08215) - 1698891..1701533 (-) 2643 WP_235083584.1 YhgE/Pip domain-containing protein -
  GOM46_RS08275 (GOM46_08220) - 1701663..1702205 (+) 543 WP_006150545.1 TetR/AcrR family transcriptional regulator -
  GOM46_RS08290 (GOM46_08235) comE 1702447..1703199 (-) 753 WP_235083585.1 competence system response regulator transcription factor ComE Regulator
  GOM46_RS08295 (GOM46_08240) comD 1703196..1704515 (-) 1320 WP_235083586.1 competence system sensor histidine kinase ComD Regulator
  GOM46_RS08305 (GOM46_08250) rlmH 1704800..1705279 (-) 480 WP_235083587.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  GOM46_RS08310 (GOM46_08255) htrA 1705463..1706638 (+) 1176 WP_235083588.1 S1C family serine protease Regulator
  GOM46_RS08315 (GOM46_08260) spo0J 1706695..1707456 (+) 762 WP_235083589.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 51230.28 Da        Isoelectric Point: 6.2473

>NTDB_id=405093 GOM46_RS08295 WP_235083586.1 1703196..1704515(-) (comD) [Streptococcus infantis strain SO]
MDLLKILIVILHIFILTNSYELICKATKKERYLFISWVFILQSIVEILFYLTSLHGLGMEKISFTCIIFAYLIGFKKYNK
FKAIFISLLLSLLYQSTHTFIAVIISSITGDSFLIKYEDLFFVVVLMLTYFITKKIITYFHLELTYFDKDYLYPFFKKVI
LIFFTLQVLLFISDMVGIHAHFNNFSSILATIVFICLLLIFFAMNAHKVQAEREIALKQKKFEQEHLQTYTDEIVSLYNE
IRGFRHDYAGMLVSMQMAIDSGDLQEIDRIYNKVLVKANQKLRSDKYTYFDLNNIEDSALRSLIARSIVYAQNNDVEFTL
EVKDVVTRLSIDLLDLVRIMSVLLNNAVEGAAESYLKQMEVAVIKMDLETVIVIQNSCNIVMNPSEDLFELGFSTKGRNR
GIGLNNVKEILDKYENIILETEMEDSTFRQIIRFKREFE

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=405093 GOM46_RS08295 WP_235083586.1 1703196..1704515(-) (comD) [Streptococcus infantis strain SO]
ATGGATTTATTGAAAATACTCATAGTTATTCTTCATATTTTTATTCTAACAAATAGCTATGAACTCATTTGTAAGGCAAC
AAAAAAAGAAAGATATCTGTTTATTTCTTGGGTATTTATATTACAGTCTATTGTTGAAATTTTATTCTATTTAACTTCTT
TACATGGATTAGGAATGGAAAAAATTTCATTTACCTGTATTATCTTTGCTTATTTAATAGGATTTAAAAAATATAATAAG
TTCAAAGCTATTTTTATTAGTTTATTATTGTCTTTATTATATCAAAGTACTCATACATTTATAGCAGTAATCATATCCTC
TATAACAGGTGATTCTTTCTTAATAAAATATGAAGATTTATTTTTTGTAGTGGTTTTGATGCTGACGTATTTTATCACTA
AAAAAATTATTACTTATTTTCATCTTGAACTTACTTATTTTGATAAAGATTACCTTTATCCATTTTTCAAAAAGGTCATT
TTAATTTTCTTTACTTTACAAGTTCTATTATTCATTTCAGATATGGTGGGTATTCATGCTCATTTTAATAATTTCAGTAG
TATTTTAGCAACAATTGTCTTTATTTGTTTATTACTAATCTTCTTTGCAATGAACGCTCATAAGGTTCAAGCTGAAAGAG
AGATCGCTCTAAAACAGAAGAAATTTGAACAAGAACATTTACAGACTTACACTGATGAAATTGTTAGTTTGTATAATGAA
ATCCGCGGTTTTCGTCATGACTATGCAGGAATGCTTGTCAGTATGCAAATGGCAATTGACAGCGGTGATTTACAGGAAAT
TGACAGAATTTACAATAAAGTTTTAGTGAAAGCTAATCAGAAATTGCGTTCAGATAAATATACCTACTTTGATTTAAATA
ACATAGAAGATTCAGCTTTACGAAGTTTGATTGCTCGATCCATTGTATATGCACAAAATAATGATGTGGAGTTTACACTT
GAGGTAAAGGATGTTGTTACAAGATTGTCAATCGATTTACTCGATCTTGTTCGGATTATGAGTGTTTTGCTAAACAACGC
TGTTGAAGGTGCTGCAGAAAGTTATTTGAAACAAATGGAAGTTGCAGTGATTAAGATGGATTTGGAGACAGTTATCGTGA
TTCAAAATTCATGTAATATCGTTATGAATCCTTCGGAAGATTTATTTGAGCTAGGTTTTTCTACAAAGGGTAGAAATAGA
GGAATAGGTCTTAATAATGTTAAAGAAATTTTGGATAAGTATGAAAATATCATTTTAGAAACAGAGATGGAAGATAGTAC
ATTTAGACAGATTATTAGATTTAAGAGAGAGTTTGAATGA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(333-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD Streptococcus mitis NCTC 12261

70.748

100

0.711
  comD/comD2 Streptococcus pneumoniae TIGR4

69.841

100

0.702
  comD/comD1 Streptococcus pneumoniae D39

68.481

100

0.688
  comD/comD1 Streptococcus pneumoniae R6

68.481

100

0.688
  comD/comD1 Streptococcus pneumoniae Rx1

68.481

100

0.688
  comD Streptococcus mitis SK321

67.347

100

0.677
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

49.326

84.51

0.417
  comD/comD2 Streptococcus gordonii strain NCTC7865

48.276

85.877

0.415

Multiple sequence alignment