Detailed information NTG0405094

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: GOM46_RS08310
• Genome accession: NZ_CP046525
• Coordinates: 1705463..1706638 (+)
• Length: 391 a.a.
• NCBI ID: WP_235083588.1
• Uniprot ID: -
• Organism: Streptococcus infantis strain SO
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1700463..1711638

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GOM46_RS08275 (GOM46_08220)	-	1701663..1702205 (+)	543	WP_006150545.1	TetR/AcrR family transcriptional regulator	-
GOM46_RS08290 (GOM46_08235)	comE	1702447..1703199 (-)	753	WP_235083585.1	competence system response regulator transcription factor ComE	Regulator
GOM46_RS08295 (GOM46_08240)	comD	1703196..1704515 (-)	1320	WP_235083586.1	competence system sensor histidine kinase ComD	Regulator
GOM46_RS08305 (GOM46_08250)	rlmH	1704800..1705279 (-)	480	WP_235083587.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
GOM46_RS08310 (GOM46_08255)	htrA	1705463..1706638 (+)	1176	WP_235083588.1	S1C family serine protease	Regulator
GOM46_RS08315 (GOM46_08260)	spo0J	1706695..1707456 (+)	762	WP_235083589.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 391 a.a.
• Molecular weight: 41381.46 Da
• Isoelectric Point: 5.7675

>NTDB_id=405094 GOM46_RS08310 WP_235083588.1 1705463..1706638(+) (htrA) [Streptococcus infantis strain SO]
MKKNLKKWGQLLLIILISFFSGILGTFTTLQLSQKQNSGTTTTTTVSKAAVKNENSTTQAVDKVKDAVVSVITYSSNSQN
SLITSDETDMDTNAEQVFSEGSGVIYKKEGDTAYIVTNTHVINGAKKVDIRLADGTKVPGDIVGSDTYSDIAVVKIAADK
VTTVAEFGDSNQLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAISTNAIQTDTAINPGNSGGPLINIQ
GQVIGITSSKIASNGGTSVEGLGFAIPANDVINIIKQLEKDGKVTRPALGIHMVNLSNLNTTDLQKLKLPGNVTSGVAVR
SVQKNMPANGHLQQYDVITKIDDKAISSTTELQSALYSHSIGDEMTVTYYRNGKEETTKIKLDKSTSDLNQ

Nucleotide

• Length: 1176 bp

>NTDB_id=405094 GOM46_RS08310 WP_235083588.1 1705463..1706638(+) (htrA) [Streptococcus infantis strain SO]
ATGAAGAAAAACTTAAAAAAATGGGGACAACTTTTATTAATCATTCTCATTAGCTTTTTTAGTGGTATTTTAGGTACTTT
TACAACATTACAGCTCAGTCAAAAACAAAATAGTGGTACGACAACTACCACTACTGTCAGTAAAGCAGCTGTAAAAAATG
AAAACTCAACTACACAAGCAGTCGATAAAGTTAAAGATGCTGTTGTATCTGTCATTACTTACTCATCAAACTCTCAAAAC
AGTTTAATCACATCTGATGAAACTGATATGGATACCAATGCTGAACAAGTATTCAGTGAAGGTTCTGGTGTCATTTATAA
AAAGGAAGGGGATACTGCTTATATTGTAACAAATACTCACGTTATTAATGGCGCTAAAAAAGTTGATATTCGTTTAGCAG
ATGGTACAAAAGTTCCTGGTGATATTGTGGGTTCTGATACTTATTCAGATATTGCTGTTGTAAAAATTGCTGCAGATAAG
GTCACAACAGTGGCCGAATTTGGTGATTCTAATCAACTAACAGTTGGAGAAACAGCTATTGCAATCGGAAGTCCCCTAGG
TTCTGAATATGCCAATACTGTGACACAAGGGATTGTATCAAGTTTAAATAGAAATGTCTCTCTAAAATCCGAAGATGGAC
AAGCTATCTCAACCAATGCTATCCAAACAGATACAGCTATTAACCCTGGTAACTCAGGTGGTCCTTTGATTAATATCCAA
GGCCAAGTTATCGGTATTACATCAAGTAAGATTGCCTCTAATGGTGGAACATCTGTCGAAGGTCTTGGTTTTGCAATTCC
TGCAAACGACGTAATCAACATTATTAAACAATTAGAAAAAGATGGAAAAGTAACTCGACCTGCTCTTGGAATCCACATGG
TTAACTTATCAAATCTTAATACAACTGATCTTCAAAAACTAAAACTTCCTGGAAATGTTACTTCTGGTGTAGCTGTTCGT
TCTGTTCAAAAAAATATGCCTGCCAATGGACATCTGCAACAATATGACGTCATTACAAAAATAGATGATAAAGCTATTTC
TTCCACTACTGAATTACAAAGTGCTCTATATAGCCACTCTATTGGAGATGAAATGACTGTAACTTATTACCGTAATGGTA
AAGAAGAAACAACTAAAATCAAGTTGGACAAGAGTACTAGTGATTTAAATCAATAG

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (101-246)

• PDZ domain (PDZ_2) (287-382)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mitis NCTC 12261	76.923	99.744	0.767
htrA	Streptococcus pneumoniae Rx1	76.154	99.744	0.76
htrA	Streptococcus pneumoniae D39	76.154	99.744	0.76
htrA	Streptococcus pneumoniae R6	76.154	99.744	0.76
htrA	Streptococcus pneumoniae TIGR4	76.154	99.744	0.76
htrA	Streptococcus gordonii str. Challis substr. CH1	67.347	100	0.675
htrA	Streptococcus mutans UA159	53.435	100	0.537