Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   GOM46_RS01120 Genome accession   NZ_CP046525
Coordinates   223151..224194 (+) Length   347 a.a.
NCBI ID   WP_235083712.1    Uniprot ID   -
Organism   Streptococcus infantis strain SO     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 218151..229194
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM46_RS01105 (GOM46_01090) nagA 220543..221694 (+) 1152 WP_006150219.1 N-acetylglucosamine-6-phosphate deacetylase -
  GOM46_RS01110 (GOM46_01095) - 221860..222237 (+) 378 WP_006150119.1 DUF1033 family protein -
  GOM46_RS01115 (GOM46_01100) comGA/cglA/cilD 222289..223227 (+) 939 WP_235083711.1 competence type IV pilus ATPase ComGA Machinery gene
  GOM46_RS01120 (GOM46_01105) comGB/cglB 223151..224194 (+) 1044 WP_235083712.1 competence type IV pilus assembly protein ComGB Machinery gene
  GOM46_RS01125 (GOM46_01110) comGC/cglC 224195..224518 (+) 324 WP_235083713.1 competence type IV pilus major pilin ComGC Machinery gene
  GOM46_RS01130 (GOM46_01115) comGD/cglD 224481..224915 (+) 435 WP_029689590.1 competence type IV pilus minor pilin ComGD Machinery gene
  GOM46_RS01135 (GOM46_01120) comGE/cglE 224878..225180 (+) 303 WP_025169999.1 competence type IV pilus minor pilin ComGE Machinery gene
  GOM46_RS01140 (GOM46_01125) comGF/cglF 225143..225604 (+) 462 WP_235083714.1 competence type IV pilus minor pilin ComGF Machinery gene
  GOM46_RS01145 (GOM46_01130) comGG 225582..226019 (+) 438 WP_235083715.1 competence type IV pilus minor pilin ComGG -
  GOM46_RS01150 (GOM46_01135) - 226078..226779 (+) 702 WP_235083716.1 histidine phosphatase family protein -
  GOM46_RS01155 (GOM46_01140) - 226971..228677 (+) 1707 WP_235083717.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 347 a.a.        Molecular weight: 39891.22 Da        Isoelectric Point: 9.9728

>NTDB_id=405037 GOM46_RS01120 WP_235083712.1 223151..224194(+) (comGB/cglB) [Streptococcus infantis strain SO]
MNKLTNFLKKDISLPFKLKRRKLATSKQKKIITLFNNLFSSGFHLVEITSFLDRSHLLEKEYVSQMRLGLSQGKSFSEMM
RTLGFSSAIVTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPVILLAFLLVIMLGLRNYLLPQLDSSNIATL
VISNLPQIFLGLTLVVALAFLTGLIFYRKSRKIQVFSFLARIPFIGVFIQYYLTAYYAREWGNMIGQGLELSQIFQMMQE
QGNPLFKEIGLDLSQSLQNGHEFSKVVQDYPFFRRELGLIIEYGEVKSKLGSELEIYAEKTWESFFTRVNRTMNLVQPLV
FIFVALLIVLLYAAMLLPMYQNMEVNF

Nucleotide


Download         Length: 1044 bp        

>NTDB_id=405037 GOM46_RS01120 WP_235083712.1 223151..224194(+) (comGB/cglB) [Streptococcus infantis strain SO]
ATGAACAAATTGACCAACTTCTTAAAGAAGGACATATCACTACCATTCAAGCTGAAACGGAGAAAATTAGCCACTAGTAA
GCAGAAGAAAATCATCACTCTCTTTAACAATTTATTTTCGAGTGGTTTTCACTTGGTAGAAATCACTTCCTTCTTAGATA
GAAGTCATTTGTTGGAAAAGGAATATGTATCTCAGATGCGCTTAGGACTCTCGCAGGGGAAATCCTTCTCGGAAATGATG
AGGACTTTAGGTTTTTCGAGTGCGATTGTCACGCAACTTTCATTGGCTGAAGTTCATGGAAATCTTCATTTGAGTTTAGG
GAAAATTGAAGAGTATCTTGATAATCTTGCTAAGGTGAAGAAGAAGTTAATTGAAGTTGCGACCTATCCAGTCATTTTGT
TAGCTTTCTTATTGGTAATTATGTTGGGTTTGCGAAATTATCTCTTGCCCCAACTGGATAGTAGTAATATAGCTACCTTA
GTGATTAGTAACTTGCCACAGATTTTTCTCGGACTGACTCTAGTAGTAGCACTCGCATTTTTAACAGGATTGATTTTCTA
CAGAAAATCTAGGAAGATACAAGTCTTTTCTTTTCTGGCTAGAATTCCTTTTATCGGTGTGTTTATTCAGTATTATCTGA
CTGCCTATTATGCTAGAGAATGGGGAAATATGATTGGACAAGGATTAGAATTGTCACAGATTTTCCAGATGATGCAGGAG
CAGGGCAATCCACTTTTTAAGGAAATTGGTTTGGATTTATCTCAGTCATTACAAAATGGTCATGAATTTTCTAAAGTTGT
TCAAGATTATCCCTTCTTTAGAAGAGAATTGGGATTAATCATTGAATATGGAGAGGTCAAATCCAAGTTGGGAAGCGAAT
TGGAAATCTATGCGGAAAAAACTTGGGAATCATTCTTTACCCGAGTCAATCGGACCATGAACCTAGTTCAACCGCTGGTG
TTTATTTTTGTAGCCCTACTAATCGTTTTATTGTACGCAGCTATGTTGCTGCCAATGTATCAAAATATGGAGGTAAATTT
TTAG

Domains

Predicted by InterProScan.

Type II secretion system (T2SS), protein F (T2SSF)

(34-150)

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus mitis SK321

81.306

97.118

0.79
  comGB/cglB Streptococcus pneumoniae Rx1

80.415

97.118

0.781
  comGB/cglB Streptococcus pneumoniae D39

80.415

97.118

0.781
  comGB/cglB Streptococcus pneumoniae R6

80.415

97.118

0.781
  comGB/cglB Streptococcus pneumoniae TIGR4

80.415

97.118

0.781
  comGB/cglB Streptococcus mitis NCTC 12261

80.119

97.118

0.778
  comYB Streptococcus gordonii str. Challis substr. CH1

70.435

99.424

0.7
  comYB Streptococcus mutans UA140

58.187

98.559

0.573
  comYB Streptococcus mutans UA159

58.187

98.559

0.573
  comGB Lactococcus lactis subsp. cremoris KW2

50.148

97.118

0.487

Multiple sequence alignment