Detailed information NTG0405041

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: GOM46_RS01140
• Genome accession: NZ_CP046525
• Coordinates: 225143..225604 (+)
• Length: 153 a.a.
• NCBI ID: WP_235083714.1
• Uniprot ID: -
• Organism: Streptococcus infantis strain SO
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 220143..230604

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GOM46_RS01105 (GOM46_01090)	nagA	220543..221694 (+)	1152	WP_006150219.1	N-acetylglucosamine-6-phosphate deacetylase	-
GOM46_RS01110 (GOM46_01095)	-	221860..222237 (+)	378	WP_006150119.1	DUF1033 family protein	-
GOM46_RS01115 (GOM46_01100)	comGA/cglA/cilD	222289..223227 (+)	939	WP_235083711.1	competence type IV pilus ATPase ComGA	Machinery gene
GOM46_RS01120 (GOM46_01105)	comGB/cglB	223151..224194 (+)	1044	WP_235083712.1	competence type IV pilus assembly protein ComGB	Machinery gene
GOM46_RS01125 (GOM46_01110)	comGC/cglC	224195..224518 (+)	324	WP_235083713.1	competence type IV pilus major pilin ComGC	Machinery gene
GOM46_RS01130 (GOM46_01115)	comGD/cglD	224481..224915 (+)	435	WP_029689590.1	competence type IV pilus minor pilin ComGD	Machinery gene
GOM46_RS01135 (GOM46_01120)	comGE/cglE	224878..225180 (+)	303	WP_025169999.1	competence type IV pilus minor pilin ComGE	Machinery gene
GOM46_RS01140 (GOM46_01125)	comGF/cglF	225143..225604 (+)	462	WP_235083714.1	competence type IV pilus minor pilin ComGF	Machinery gene
GOM46_RS01145 (GOM46_01130)	comGG	225582..226019 (+)	438	WP_235083715.1	competence type IV pilus minor pilin ComGG	-
GOM46_RS01150 (GOM46_01135)	-	226078..226779 (+)	702	WP_235083716.1	histidine phosphatase family protein	-
GOM46_RS01155 (GOM46_01140)	-	226971..228677 (+)	1707	WP_235083717.1	ABC transporter ATP-binding protein	-
GOM46_RS01160 (GOM46_01145)	-	228679..230445 (+)	1767	WP_235083718.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 18181.89 Da
• Isoelectric Point: 9.9260

>NTDB_id=405041 GOM46_RS01140 WP_235083714.1 225143..225604(+) (comGF/cglF) [Streptococcus infantis strain SO]
MELKNYWRFKISRVRAFTLLESLVALIVISGSLLLFQSMSQLLVSEVRYQQKSEQKEWLLFVDQLEAELNRTQFEKVEND
RLYIKQDGKSISMGKSKSNDFRKTDASGRGYQPMIYGLKSAHIYQKGQNVHFYFQFEKGLEREFIYRVEKEKS

Nucleotide

• Length: 462 bp

>NTDB_id=405041 GOM46_RS01140 WP_235083714.1 225143..225604(+) (comGF/cglF) [Streptococcus infantis strain SO]
ATGGAACTGAAAAATTACTGGCGATTCAAGATAAGTAGAGTCAGAGCCTTTACTCTTTTAGAATCCCTGGTTGCTCTTAT
TGTGATTAGTGGGAGTTTACTTCTTTTTCAATCTATGAGTCAACTCTTGGTTTCAGAAGTTCGCTACCAGCAGAAAAGTG
AGCAGAAGGAATGGCTCTTATTTGTGGATCAGCTGGAAGCAGAGTTGAATCGAACTCAATTTGAAAAAGTGGAGAATGAT
AGACTTTACATTAAACAGGATGGGAAATCTATCTCTATGGGTAAATCAAAGTCAAATGATTTTCGGAAAACAGATGCCAG
TGGACGTGGTTATCAACCTATGATCTACGGTCTGAAATCAGCTCATATTTACCAAAAAGGGCAAAATGTTCATTTTTATT
TTCAGTTTGAAAAGGGACTTGAGAGGGAGTTTATCTATCGTGTGGAAAAAGAAAAAAGTTAG

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (46-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus mitis NCTC 12261	77.852	97.386	0.758
comGF/cglF	Streptococcus mitis SK321	77.181	97.386	0.752
comGF/cglF	Streptococcus pneumoniae Rx1	75.839	97.386	0.739
comGF/cglF	Streptococcus pneumoniae D39	75.839	97.386	0.739
comGF/cglF	Streptococcus pneumoniae R6	75.839	97.386	0.739
comGF/cglF	Streptococcus pneumoniae TIGR4	75.839	97.386	0.739
comYF	Streptococcus mutans UA159	42.222	88.235	0.373
comYF	Streptococcus mutans UA140	41.481	88.235	0.366