Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   GOM46_RS01115 Genome accession   NZ_CP046525
Coordinates   222289..223227 (+) Length   312 a.a.
NCBI ID   WP_235083711.1    Uniprot ID   -
Organism   Streptococcus infantis strain SO     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 217289..228227
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM46_RS01100 (GOM46_01085) - 217344..219962 (+) 2619 WP_235083710.1 SEC10/PgrA surface exclusion domain-containing protein -
  GOM46_RS01105 (GOM46_01090) nagA 220543..221694 (+) 1152 WP_006150219.1 N-acetylglucosamine-6-phosphate deacetylase -
  GOM46_RS01110 (GOM46_01095) - 221860..222237 (+) 378 WP_006150119.1 DUF1033 family protein -
  GOM46_RS01115 (GOM46_01100) comGA/cglA/cilD 222289..223227 (+) 939 WP_235083711.1 competence type IV pilus ATPase ComGA Machinery gene
  GOM46_RS01120 (GOM46_01105) comGB/cglB 223151..224194 (+) 1044 WP_235083712.1 competence type IV pilus assembly protein ComGB Machinery gene
  GOM46_RS01125 (GOM46_01110) comGC/cglC 224195..224518 (+) 324 WP_235083713.1 competence type IV pilus major pilin ComGC Machinery gene
  GOM46_RS01130 (GOM46_01115) comGD/cglD 224481..224915 (+) 435 WP_029689590.1 competence type IV pilus minor pilin ComGD Machinery gene
  GOM46_RS01135 (GOM46_01120) comGE/cglE 224878..225180 (+) 303 WP_025169999.1 competence type IV pilus minor pilin ComGE Machinery gene
  GOM46_RS01140 (GOM46_01125) comGF/cglF 225143..225604 (+) 462 WP_235083714.1 competence type IV pilus minor pilin ComGF Machinery gene
  GOM46_RS01145 (GOM46_01130) comGG 225582..226019 (+) 438 WP_235083715.1 competence type IV pilus minor pilin ComGG -
  GOM46_RS01150 (GOM46_01135) - 226078..226779 (+) 702 WP_235083716.1 histidine phosphatase family protein -

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 35500.46 Da        Isoelectric Point: 6.5661

>NTDB_id=405036 GOM46_RS01115 WP_235083711.1 222289..223227(+) (comGA/cglA/cilD) [Streptococcus infantis strain SO]
MVQALAQELISLAKKNGAQDIYFVPKNQVYELHMRIGDKRHLIDTYDFEKLGSVISHFKFITGMNVGEKRRSQLGSCDYQ
HDDKVSSLRLSTVGDYRGHESLVIRLLHDQEQELHFWFQNLKELEKGFRQRGLYLFAGPVGSGKTTLMHELAKSLFKGQQ
VMSIEDPVEIKQEEMLQLQLNEAIGLNYENLIKLSLRHRPDLLIIGEIRDSETARAVVRASLTGATVFSTIHAKSVRGVY
ERLVELGVSEDELAVVLQGVCYQRLIGGGGIIDFANQNYQEHQANKWNEQIDQLLKEGHITTIQAETEKISH

Nucleotide


Download         Length: 939 bp        

>NTDB_id=405036 GOM46_RS01115 WP_235083711.1 222289..223227(+) (comGA/cglA/cilD) [Streptococcus infantis strain SO]
ATGGTACAAGCACTTGCACAAGAATTGATTAGTCTCGCAAAAAAGAATGGAGCGCAGGACATTTATTTTGTTCCCAAGAA
TCAGGTTTATGAGCTACATATGCGAATTGGAGATAAAAGACATCTAATTGATACCTATGATTTTGAAAAGTTGGGGTCTG
TCATTAGTCACTTTAAGTTTATTACGGGGATGAACGTAGGCGAAAAACGTCGTAGCCAGCTTGGTTCCTGTGACTATCAG
CATGATGACAAGGTTTCTTCACTCCGTTTATCAACTGTAGGAGATTATCGTGGGCATGAGAGTCTAGTTATTCGACTTTT
ACATGACCAAGAACAAGAGTTGCACTTCTGGTTTCAGAACCTTAAGGAACTGGAAAAGGGCTTTAGACAACGCGGGCTTT
ATCTTTTTGCAGGCCCTGTAGGAAGTGGGAAAACGACTCTAATGCATGAGTTAGCTAAGTCATTGTTCAAGGGACAGCAA
GTCATGTCCATTGAAGACCCAGTCGAGATTAAGCAGGAAGAGATGCTACAATTACAACTTAATGAAGCAATTGGGCTGAA
CTATGAAAATTTGATAAAACTCTCCCTACGGCATCGTCCAGACCTTTTAATTATTGGAGAAATTCGGGATAGTGAAACAG
CCCGTGCTGTTGTACGAGCCAGTTTAACAGGGGCTACAGTATTCTCGACTATTCATGCAAAGAGTGTTCGTGGGGTCTAT
GAGCGCCTTGTGGAACTTGGAGTTAGTGAAGATGAACTCGCAGTTGTTTTACAAGGTGTTTGTTACCAGAGACTAATTGG
GGGAGGAGGAATTATCGATTTTGCAAACCAAAATTATCAGGAACACCAGGCAAACAAATGGAATGAACAAATTGACCAAC
TTCTTAAAGAAGGACATATCACTACCATTCAAGCTGAAACGGAGAAAATTAGCCACTAG

Domains

Predicted by InterProScan.

Type II/IV secretion system protein (T2SSE)

(11-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

83.654

100

0.837
  comGA/cglA/cilD Streptococcus pneumoniae D39

83.654

100

0.837
  comGA/cglA/cilD Streptococcus pneumoniae R6

83.654

100

0.837
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

83.654

100

0.837
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

83.654

100

0.837
  comYA Streptococcus gordonii str. Challis substr. CH1

76.774

99.359

0.763
  comYA Streptococcus mutans UA159

63.987

99.679

0.638
  comYA Streptococcus mutans UA140

63.987

99.679

0.638
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

63.226

99.359

0.628
  comGA Lactococcus lactis subsp. cremoris KW2

55.449

100

0.554
  comGA Latilactobacillus sakei subsp. sakei 23K

43.446

85.577

0.372

Multiple sequence alignment