Detailed information NTG0404955

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: GOM48_RS09735
• Genome accession: NZ_CP046523
• Coordinates: 1936610..1937800 (+)
• Length: 396 a.a.
• NCBI ID: WP_235097593.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain SOD
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1931610..1942800

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GOM48_RS09695 (GOM48_09630)	-	1932678..1933220 (+)	543	WP_235097583.1	TetR/AcrR family transcriptional regulator	-
GOM48_RS09710 (GOM48_09645)	comE	1933460..1934212 (-)	753	WP_235097585.1	competence system response regulator transcription factor ComE	Regulator
GOM48_RS09715 (GOM48_09650)	comD	1934209..1935528 (-)	1320	WP_235097586.1	competence system sensor histidine kinase ComD	Regulator
GOM48_RS09720 (GOM48_09655)	comC	1935541..1935663 (-)	123	WP_235097589.1	competence-stimulating peptide ComC	Regulator
GOM48_RS09730 (GOM48_09665)	rlmH	1935946..1936425 (-)	480	WP_235097591.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
GOM48_RS09735 (GOM48_09670)	htrA	1936610..1937800 (+)	1191	WP_235097593.1	S1C family serine protease	Regulator
GOM48_RS09740 (GOM48_09675)	spo0J	1937858..1938616 (+)	759	WP_235097595.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 396 a.a.
• Molecular weight: 41845.78 Da
• Isoelectric Point: 6.8893

>NTDB_id=404955 GOM48_RS09735 WP_235097593.1 1936610..1937800(+) (htrA) [Streptococcus oralis strain SOD]
MKHLQKFYKKGVTFLIIILIGFLSGALGSFVTLQLYQKQVSQATNNTTNTVTQTSYKNENATTQAVNKVKDAVVSVITYS
SNRQNSVFGNDETDTDTDSQQVASEGSGVIYKKNGKDAYLVTNTHVIKGASKVDIRLADGTKVPGEIVGSDTFSDIAVVK
ISSEKVTTVAEFGDSSKLNVGETAIAIGSPLGSEYANTVTQGIISSLNRNVSLKSQDGQAISTKAIQTDTAINPGNSGGP
LVNIQGQVIGITSSKIASNGGTSVEGLGFAIPSNDAQNIIKQLESDGKVTRPALGIQMVNLANIGASDLRKLNIPSSVTS
GVVVKSVQSNMPASGHLEKYDVITKVDDKETSSSTDLQSALYNHSIGDTIKITYYRNGKEETTTVKLDKSTSDLES

Nucleotide

• Length: 1191 bp

>NTDB_id=404955 GOM48_RS09735 WP_235097593.1 1936610..1937800(+) (htrA) [Streptococcus oralis strain SOD]
ATGAAACACTTACAAAAATTTTACAAAAAAGGAGTTACCTTTCTTATCATCATTCTGATAGGATTTTTGAGTGGTGCCCT
AGGAAGTTTTGTGACACTGCAACTTTATCAAAAACAAGTAAGTCAAGCCACAAATAACACTACAAACACTGTTACTCAGA
CTTCCTACAAAAATGAAAATGCAACAACTCAGGCCGTTAATAAGGTAAAAGATGCCGTTGTGTCGGTCATCACTTATTCA
TCAAATCGACAAAATAGTGTTTTTGGAAATGACGAGACAGATACGGATACCGACTCTCAACAGGTAGCAAGTGAAGGTTC
TGGTGTTATTTACAAAAAGAATGGGAAAGATGCCTACCTTGTGACAAATACCCACGTTATTAAAGGAGCTTCAAAAGTTG
ATATCCGTTTAGCAGACGGTACAAAAGTTCCTGGTGAAATTGTCGGTTCTGATACGTTCTCTGATATTGCTGTCGTAAAA
ATTTCTTCAGAAAAAGTCACAACCGTAGCAGAATTTGGAGATTCTAGCAAGCTTAATGTCGGAGAAACTGCAATCGCAAT
TGGTAGTCCTCTGGGCTCAGAATATGCCAATACAGTTACCCAAGGAATCATTTCAAGTCTCAATCGAAATGTCTCTCTAA
AATCTCAAGATGGTCAAGCGATTTCTACAAAAGCTATTCAGACAGATACTGCTATTAACCCTGGTAACTCTGGTGGTCCA
CTTGTAAACATTCAGGGCCAAGTTATCGGGATTACATCAAGTAAAATTGCAAGTAATGGTGGAACCTCTGTCGAAGGTCT
TGGTTTTGCAATCCCATCAAATGATGCTCAAAATATTATTAAACAGCTTGAAAGTGATGGTAAAGTGACTCGCCCTGCTC
TTGGAATTCAAATGGTTAATTTAGCTAATATCGGAGCTAGTGATCTTAGAAAACTCAATATTCCAAGTAGCGTAACTTCT
GGTGTAGTGGTAAAATCTGTTCAAAGTAATATGCCTGCATCTGGTCACCTTGAAAAATACGACGTTATTACCAAAGTTGA
CGACAAGGAGACTTCTTCGTCAACAGATTTACAGAGTGCTCTTTACAACCATTCTATCGGAGACACCATTAAAATCACCT
ACTATCGAAATGGGAAAGAGGAGACTACAACTGTTAAACTAGATAAAAGTACAAGTGATTTAGAATCTTAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (106-251)

• PDZ domain (PDZ_2) (292-387)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mitis NCTC 12261	84.343	100	0.843
htrA	Streptococcus pneumoniae Rx1	83.081	100	0.831
htrA	Streptococcus pneumoniae D39	83.081	100	0.831
htrA	Streptococcus pneumoniae R6	83.081	100	0.831
htrA	Streptococcus pneumoniae TIGR4	83.081	100	0.831
htrA	Streptococcus gordonii str. Challis substr. CH1	65.578	100	0.659
htrA	Streptococcus mutans UA159	54.386	100	0.548