Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD   Type   Regulator
Locus tag   GOM48_RS09715 Genome accession   NZ_CP046523
Coordinates   1934209..1935528 (-) Length   439 a.a.
NCBI ID   WP_235097586.1    Uniprot ID   -
Organism   Streptococcus oralis strain SOD     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1929209..1940528
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM48_RS09690 (GOM48_09625) - 1929907..1932549 (-) 2643 WP_235097582.1 YhgE/Pip domain-containing protein -
  GOM48_RS09695 (GOM48_09630) - 1932678..1933220 (+) 543 WP_235097583.1 TetR/AcrR family transcriptional regulator -
  GOM48_RS09710 (GOM48_09645) comE 1933460..1934212 (-) 753 WP_235097585.1 competence system response regulator transcription factor ComE Regulator
  GOM48_RS09715 (GOM48_09650) comD 1934209..1935528 (-) 1320 WP_235097586.1 competence system sensor histidine kinase ComD Regulator
  GOM48_RS09720 (GOM48_09655) comC 1935541..1935663 (-) 123 WP_235097589.1 competence-stimulating peptide ComC Regulator
  GOM48_RS09730 (GOM48_09665) rlmH 1935946..1936425 (-) 480 WP_235097591.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  GOM48_RS09735 (GOM48_09670) htrA 1936610..1937800 (+) 1191 WP_235097593.1 S1C family serine protease Regulator
  GOM48_RS09740 (GOM48_09675) spo0J 1937858..1938616 (+) 759 WP_235097595.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 51796.55 Da        Isoelectric Point: 6.2494

>NTDB_id=404953 GOM48_RS09715 WP_235097586.1 1934209..1935528(-) (comD) [Streptococcus oralis strain SOD]
MDFFAIISVILHIFITSKSYNLICNTTRKEQYFFIFYTVIVEFVVEFFFYSIYLSGLGIEKFLYPFILYAYFIWFKKFDK
YRGVFLSFLLSLLYHSTHTFIAVTLSSITGDELALHYESIFFLVVLLLTYFVILKTIRYFHLEFKYFDKEYLYSFLKKVL
YAFIFLHIVSFISDIVSTISHLNSFGSILSTIVFICLLLIFFAMNSYKVQIEKEIALKQKKFEQKHLQTYTDEIVKLYNE
IRGFRHDYAGMLVSMQMAIDSEDLQEIDRVYKEVLVKANQKLRSEKYTYFDLNNLEDSALRSLIAQSIVYARNNDVEFTL
EVKDVITRLSMDLLDLVRIMSILLNNAVEGAADSYLKQMEVAVIKMDFETVIVIQNSCKITMTPSEDLFALGFSTKGRNR
GLGLNNVKEILDKYDNIMLETEMEDNTFRQIIRFKREFE

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=404953 GOM48_RS09715 WP_235097586.1 1934209..1935528(-) (comD) [Streptococcus oralis strain SOD]
ATGGATTTTTTCGCAATAATAAGCGTTATATTACATATTTTTATTACTAGTAAAAGTTATAATTTGATTTGTAACACAAC
TAGAAAAGAACAATACTTCTTTATTTTTTATACAGTAATAGTAGAATTTGTAGTTGAATTTTTCTTCTATTCTATATATT
TAAGTGGACTAGGGATTGAAAAATTTTTATATCCATTTATTTTATACGCTTATTTTATATGGTTTAAAAAGTTTGATAAG
TATAGGGGAGTATTCCTAAGTTTCCTACTTTCTCTCTTATATCACAGTACTCATACTTTTATAGCTGTAACGCTATCCTC
GATAACAGGTGATGAGCTTGCATTACACTATGAAAGTATATTCTTTCTAGTAGTATTGTTGTTGACTTATTTTGTTATTT
TAAAAACAATTCGTTATTTCCATTTGGAGTTTAAATATTTTGACAAAGAATATCTCTATTCTTTTTTGAAAAAAGTGCTA
TATGCATTTATCTTCTTGCATATCGTCTCTTTTATTTCAGATATCGTGAGTACTATTTCTCATTTAAATAGTTTTGGAAG
TATTTTATCAACCATTGTTTTTATTTGCTTGTTATTGATTTTCTTTGCAATGAATTCTTATAAGGTTCAAATTGAAAAAG
AGATTGCCCTAAAGCAGAAGAAATTTGAACAAAAGCATTTACAGACTTATACTGATGAAATTGTCAAGTTGTATAATGAA
ATTCGAGGTTTTCGTCATGACTATGCAGGTATGCTTGTCAGCATGCAAATGGCAATTGACAGTGAAGATTTACAGGAAAT
TGACAGAGTTTACAAGGAAGTATTAGTAAAAGCGAATCAAAAACTGCGTTCAGAAAAATATACTTACTTTGATTTGAACA
ATTTAGAAGATTCAGCTTTACGTAGTTTGATTGCTCAATCCATTGTTTATGCACGAAATAATGATGTAGAGTTTACATTG
GAAGTAAAGGATGTTATTACTAGATTGTCAATGGATTTACTTGATCTTGTTCGCATCATGAGTATTCTCTTAAACAATGC
TGTTGAAGGAGCCGCGGATAGTTACTTGAAACAAATGGAAGTTGCAGTCATTAAAATGGATTTTGAGACAGTTATAGTCA
TCCAGAATTCATGTAAAATCACTATGACGCCTTCAGAGGACTTATTTGCCTTAGGTTTCTCTACCAAGGGAAGAAATAGA
GGTTTAGGGCTTAATAATGTCAAAGAGATTCTAGATAAATATGACAACATTATGTTAGAAACAGAGATGGAAGACAACAC
ATTTAGACAAATTATTAGATTTAAGAGGGAATTCGAATGA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(332-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD Streptococcus mitis NCTC 12261

78.458

100

0.788
  comD/comD2 Streptococcus pneumoniae TIGR4

74.83

100

0.752
  comD/comD1 Streptococcus pneumoniae Rx1

74.603

100

0.749
  comD/comD1 Streptococcus pneumoniae D39

74.603

100

0.749
  comD/comD1 Streptococcus pneumoniae R6

74.603

100

0.749
  comD Streptococcus mitis SK321

73.923

100

0.743
  comD/comD2 Streptococcus gordonii strain NCTC7865

50.266

85.649

0.431
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

50.267

85.194

0.428

Multiple sequence alignment