Detailed information    

insolico Bioinformatically predicted

Overview


Name   comC   Type   Regulator
Locus tag   GOM48_RS09720 Genome accession   NZ_CP046523
Coordinates   1935541..1935663 (-) Length   40 a.a.
NCBI ID   WP_235097589.1    Uniprot ID   -
Organism   Streptococcus oralis strain SOD     
Function   binding to ComD; induce autophosphorylation of ComD (predicted from homology)   
Competence regulation

Genomic Context


Location: 1930541..1940663
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM48_RS09695 (GOM48_09630) - 1932678..1933220 (+) 543 WP_235097583.1 TetR/AcrR family transcriptional regulator -
  GOM48_RS09710 (GOM48_09645) comE 1933460..1934212 (-) 753 WP_235097585.1 competence system response regulator transcription factor ComE Regulator
  GOM48_RS09715 (GOM48_09650) comD 1934209..1935528 (-) 1320 WP_235097586.1 competence system sensor histidine kinase ComD Regulator
  GOM48_RS09720 (GOM48_09655) comC 1935541..1935663 (-) 123 WP_235097589.1 competence-stimulating peptide ComC Regulator
  GOM48_RS09730 (GOM48_09665) rlmH 1935946..1936425 (-) 480 WP_235097591.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  GOM48_RS09735 (GOM48_09670) htrA 1936610..1937800 (+) 1191 WP_235097593.1 S1C family serine protease Regulator
  GOM48_RS09740 (GOM48_09675) spo0J 1937858..1938616 (+) 759 WP_235097595.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence


Protein


Download         Length: 40 a.a.        Molecular weight: 4981.83 Da        Isoelectric Point: 10.4095

>NTDB_id=404954 GOM48_RS09720 WP_235097589.1 1935541..1935663(-) (comC) [Streptococcus oralis strain SOD]
MKNTVKLEQFKKLTEKELQEIQGGEIRKENNFLFYFFKRK

Nucleotide


Download         Length: 123 bp        

>NTDB_id=404954 GOM48_RS09720 WP_235097589.1 1935541..1935663(-) (comC) [Streptococcus oralis strain SOD]
ATGAAAAACACAGTTAAATTGGAACAGTTCAAAAAGCTTACAGAGAAAGAATTGCAGGAGATTCAAGGTGGAGAAATTAG
AAAGGAAAATAATTTTTTATTTTATTTTTTTAAAAGAAAGTAA

Domains


Predicted by InterproScan.

(1-29)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC Streptococcus mitis NCTC 12261

62.5

100

0.625

  comC Streptococcus mitis SK321

62.5

100

0.625

  comC/comC2 Streptococcus pneumoniae A66

60

100

0.6

  comC/comC2 Streptococcus pneumoniae TIGR4

60

100

0.6

  comC/comC1 Streptococcus pneumoniae R6

57.5

100

0.575

  comC/comC1 Streptococcus pneumoniae G54

57.5

100

0.575

  comC/comC1 Streptococcus pneumoniae D39

57.5

100

0.575

  comC/comC1 Streptococcus pneumoniae Rx1

57.5

100

0.575

  comC/comC2 Streptococcus gordonii strain NCTC7865

45.946

92.5

0.425


Multiple sequence alignment