Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   GFX43_RS12515 Genome accession   NZ_CP046448
Coordinates   2462712..2463962 (-) Length   416 a.a.
NCBI ID   WP_003231847.1    Uniprot ID   A0A199WIX6
Organism   Bacillus subtilis strain ZD01     
Function   unknown (predicted from homology)   
Unclear

Genomic Context

Location: 2457712..2468962
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GFX43_RS12500 (GFX43_012500) rny 2458312..2459874 (-) 1563 WP_003221010.1 ribonuclease Y -
  GFX43_RS12505 (GFX43_012505) pbpX 2460150..2461325 (-) 1176 WP_015383692.1 serine hydrolase domain-containing protein -
  GFX43_RS12510 (GFX43_012510) recA 2461493..2462539 (-) 1047 WP_003245789.1 recombinase RecA Machinery gene
  GFX43_RS12515 (GFX43_012515) cinA 2462712..2463962 (-) 1251 WP_003231847.1 competence/damage-inducible protein A Machinery gene
  GFX43_RS12520 (GFX43_012520) pgsA 2463980..2464561 (-) 582 WP_003244753.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  GFX43_RS12525 (GFX43_012525) rodZ 2464612..2465478 (-) 867 WP_010886511.1 cell shape determination protein RodZ -
  GFX43_RS12530 (GFX43_012530) - 2465545..2466336 (-) 792 WP_003220998.1 YmfK family protein -
  GFX43_RS12535 (GFX43_012535) ymfJ 2466466..2466723 (-) 258 WP_003245199.1 DUF3243 domain-containing protein -
  GFX43_RS12540 (GFX43_012540) efpI 2466804..2467532 (-) 729 WP_015483236.1 EF-P-5 aminopentanone reductase -
  GFX43_RS12545 (GFX43_012545) ymfH 2467587..2468873 (-) 1287 WP_015383690.1 pitrilysin family protein -

Sequence

Protein


Download         Length: 416 a.a.        Molecular weight: 45537.85 Da        Isoelectric Point: 5.3737

>NTDB_id=404407 GFX43_RS12515 WP_003231847.1 2462712..2463962(-) (cinA) [Bacillus subtilis strain ZD01]
MEFPKKAEIIAVGSELLLGQIANTNAQFISKQLAEIGVNVFYHTAVGDNPERLKQVIRIAEERSDFIIFSGGLGPTKDDL
TKETIANTLGRPLVLNDEAFQSIEDYFKRTKRTMSPNNRKQALVIEGSDVLANHFGMAPGMLTEHESRYYMLLPGPPSEL
RPMFENEAKPLLLKKMGSNEKIVSTVLRFFGIGESQLEADLEDIIDAQTNPTIAPLAADGEVTLRLTAKHADEKETERLL
KETEAVILERVGEFFYGYDDTSLVKELSIACKEKGITISAAESFTGGLFSEWLTDHSGASKLFAGGVVCYTNDVKQNVLG
VKKETLDRFGAVSKECASELAKGVQKLTGSDIGISFTGVAGPDAQEGHEPGHVFIGISANGKEEVHEFHFAGSRTGIRKR
GAKYGCHLILKLLEQK

Nucleotide


Download         Length: 1251 bp        

>NTDB_id=404407 GFX43_RS12515 WP_003231847.1 2462712..2463962(-) (cinA) [Bacillus subtilis strain ZD01]
ATGGAATTTCCAAAAAAAGCAGAAATAATTGCAGTCGGTTCAGAGCTGCTGCTTGGCCAAATCGCCAATACAAATGCTCA
ATTTATCAGCAAACAGCTCGCTGAAATCGGGGTCAACGTATTTTATCATACAGCGGTCGGCGATAACCCGGAGCGGCTGA
AGCAGGTCATCCGCATTGCTGAAGAACGCTCTGACTTCATTATTTTTTCAGGAGGTCTTGGACCCACAAAAGATGATCTG
ACGAAAGAAACGATTGCAAATACGCTGGGACGTCCGCTTGTGTTAAATGATGAGGCATTCCAATCCATTGAGGACTATTT
CAAACGAACAAAACGCACGATGTCACCTAATAACCGAAAACAGGCGCTTGTGATCGAAGGCTCTGACGTGCTGGCGAATC
ACTTTGGAATGGCCCCGGGAATGCTCACAGAGCATGAATCGCGCTATTATATGCTTCTTCCTGGACCGCCGAGCGAATTG
CGTCCAATGTTTGAAAACGAGGCAAAACCTCTTCTGCTGAAAAAGATGGGTTCAAATGAAAAAATTGTGTCAACCGTTCT
TCGTTTTTTCGGTATCGGTGAATCTCAGCTTGAAGCCGATTTGGAAGATATTATTGATGCGCAAACCAATCCGACAATTG
CGCCTTTGGCGGCTGATGGAGAGGTGACGCTGCGTCTGACAGCCAAACACGCCGATGAAAAGGAAACAGAGCGTCTGTTA
AAAGAAACAGAGGCCGTTATCTTAGAGCGTGTCGGTGAATTTTTCTATGGTTACGATGATACTTCTCTTGTAAAAGAGCT
ATCTATAGCGTGTAAGGAAAAAGGCATTACAATTTCTGCGGCAGAAAGCTTTACCGGAGGGCTGTTTTCTGAATGGCTGA
CGGATCATAGCGGTGCCTCAAAATTATTTGCCGGGGGCGTTGTTTGCTATACAAACGACGTGAAGCAGAATGTGCTTGGT
GTCAAGAAGGAAACATTAGATCGTTTTGGGGCGGTCAGCAAGGAGTGCGCATCCGAACTGGCTAAGGGTGTTCAAAAACT
CACTGGCAGCGATATCGGCATTAGCTTTACTGGTGTAGCAGGACCTGATGCTCAAGAAGGGCATGAGCCTGGGCATGTGT
TTATCGGCATTTCCGCAAATGGTAAAGAAGAGGTTCACGAGTTTCACTTTGCGGGCTCCAGAACGGGGATCAGAAAACGC
GGCGCTAAATACGGCTGCCATTTAATCTTAAAGCTTTTAGAGCAAAAATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(262-412)

Probable molybdopterin binding domain (MoCF_biosynth)

(9-172)

Damage-inducible protein CinA KH domain (CinA_KH)

(184-257)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A199WIX6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Bacillus subtilis subsp. subtilis str. 168

100

100

1
  cinA Streptococcus mitis NCTC 12261

45.694

100

0.459
  cinA Streptococcus mitis SK321

45.694

100

0.459
  cinA Streptococcus pneumoniae TIGR4

45.455

100

0.457
  cinA Streptococcus mutans UA159

46.005

99.279

0.457
  cinA Streptococcus pneumoniae Rx1

45.215

100

0.454
  cinA Streptococcus pneumoniae R6

45.215

100

0.454
  cinA Streptococcus pneumoniae D39

44.976

100

0.452
  cinA Streptococcus suis isolate S10

41.379

90.625

0.375

Multiple sequence alignment