Detailed information
Bioinformatically predicted
Overview
| Name | cinA | Type | Machinery gene |
| Locus tag | GM657_RS04255 | Genome accession | NZ_CP046395 |
| Coordinates | 892811..894052 (+) | Length | 413 a.a. |
| NCBI ID | WP_014569352.1 | Uniprot ID | - |
| Organism | Lacticaseibacillus rhamnosus GG strain JL-1 | ||
| Function | facilitate localization of RecA (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 884895..933782 | 892811..894052 | within | 0 |
Gene organization within MGE regions
Location: 884895..933782
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GM657_RS04225 (GM657_04415) | - | 885393..887693 (+) | 2301 | WP_014569347.1 | DNA translocase FtsK | - |
| GM657_RS04230 (GM657_04420) | yfmF | 887702..888964 (+) | 1263 | WP_014569348.1 | EF-P 5-aminopentanol modification-associated protein YfmF | - |
| GM657_RS04235 (GM657_04425) | yfmH | 888961..890253 (+) | 1293 | WP_014569349.1 | EF-P 5-aminopentanol modification-associated protein YfmH | - |
| GM657_RS04240 (GM657_04430) | ymfI | 890253..890981 (+) | 729 | WP_014569350.1 | elongation factor P 5-aminopentanone reductase | - |
| GM657_RS04245 (GM657_04435) | - | 891068..892003 (+) | 936 | WP_005688668.1 | helix-turn-helix domain-containing protein | - |
| GM657_RS04250 (GM657_04440) | pgsA | 892000..892590 (+) | 591 | WP_014569351.1 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase | - |
| GM657_RS04255 (GM657_04445) | cinA | 892811..894052 (+) | 1242 | WP_014569352.1 | competence/damage-inducible protein A | Machinery gene |
| GM657_RS04260 (GM657_04450) | recA | 894104..895156 (+) | 1053 | WP_005688187.1 | recombinase RecA | Machinery gene |
| GM657_RS04265 (GM657_04460) | rny | 895781..897352 (+) | 1572 | WP_005684479.1 | ribonuclease Y | - |
| GM657_RS04270 (GM657_04465) | - | 897441..898097 (-) | 657 | WP_029943817.1 | YigZ family protein | - |
| GM657_RS04275 (GM657_04470) | - | 898125..899390 (+) | 1266 | WP_014569356.1 | DEAD/DEAH box helicase | - |
| GM657_RS04280 (GM657_04475) | - | 899549..900067 (+) | 519 | WP_005688681.1 | ComF family protein | - |
| GM657_RS04285 (GM657_04480) | hpf | 900259..900816 (+) | 558 | WP_005684485.1 | ribosome hibernation-promoting factor, HPF/YfiA family | - |
| GM657_RS04295 (GM657_04490) | secA | 901399..903762 (+) | 2364 | WP_005684487.1 | preprotein translocase subunit SecA | - |
| GM657_RS04300 (GM657_04495) | prfB | 903904..905020 (+) | 1117 | WP_154241369.1 | peptide chain release factor 2 | - |
| GM657_RS04305 (GM657_04500) | ftsE | 905097..905783 (+) | 687 | WP_005684489.1 | cell division ATP-binding protein FtsE | - |
| GM657_RS04310 (GM657_04505) | ftsX | 905773..906660 (+) | 888 | WP_005684490.1 | permease-like cell division protein FtsX | - |
| GM657_RS04315 | - | 906738..906875 (+) | 138 | WP_014569359.1 | hypothetical protein | - |
| GM657_RS04320 (GM657_04510) | - | 906931..908028 (+) | 1098 | WP_014569360.1 | PDZ domain-containing protein | - |
| GM657_RS04325 (GM657_04515) | - | 908025..908729 (+) | 705 | WP_005688690.1 | response regulator transcription factor | - |
| GM657_RS04330 (GM657_04520) | pnpS | 908722..910389 (+) | 1668 | WP_014569361.1 | two-component system histidine kinase PnpS | - |
| GM657_RS04335 (GM657_04525) | - | 910479..911345 (+) | 867 | WP_005684496.1 | phosphate ABC transporter substrate-binding protein PstS family protein | - |
| GM657_RS04340 (GM657_04530) | pstC | 911493..912416 (+) | 924 | WP_005684497.1 | phosphate ABC transporter permease subunit PstC | - |
| GM657_RS04345 (GM657_04535) | pstA | 912413..913297 (+) | 885 | WP_005684499.1 | phosphate ABC transporter permease PstA | - |
| GM657_RS04350 (GM657_04540) | pstB | 913368..914186 (+) | 819 | WP_005713669.1 | phosphate ABC transporter ATP-binding protein PstB | - |
| GM657_RS04355 (GM657_04545) | pstB | 914196..914960 (+) | 765 | WP_005684501.1 | phosphate ABC transporter ATP-binding protein PstB | - |
| GM657_RS04360 (GM657_04550) | phoU | 914971..915648 (+) | 678 | WP_005684502.1 | phosphate signaling complex protein PhoU | - |
| GM657_RS04365 (GM657_04555) | - | 915902..916780 (-) | 879 | WP_048653158.1 | IS3 family transposase | - |
| GM657_RS04370 (GM657_04560) | - | 916777..917505 (-) | 729 | WP_014569363.1 | helix-turn-helix domain-containing protein | - |
| GM657_RS04375 (GM657_04565) | liaX | 918074..919564 (+) | 1491 | WP_014569364.1 | daptomycin-sensing surface protein LiaX | - |
| GM657_RS04380 (GM657_04570) | - | 919576..919836 (+) | 261 | WP_005688700.1 | hypothetical protein | - |
| GM657_RS04385 (GM657_04575) | - | 919839..920174 (+) | 336 | WP_005684507.1 | phage holin family protein | - |
| GM657_RS04390 (GM657_04580) | hprK | 920441..921400 (+) | 960 | WP_005684508.1 | HPr(Ser) kinase/phosphatase | - |
| GM657_RS04395 (GM657_04585) | lgt | 921402..922229 (+) | 828 | WP_014569365.1 | prolipoprotein diacylglyceryl transferase | - |
| GM657_RS04400 (GM657_04590) | - | 922240..923295 (+) | 1056 | WP_014569366.1 | NAD(P)H-dependent glycerol-3-phosphate dehydrogenase | - |
| GM657_RS04405 (GM657_04595) | trxB | 923361..924308 (+) | 948 | WP_005684511.1 | thioredoxin-disulfide reductase | - |
| GM657_RS04410 (GM657_04600) | - | 924560..926287 (+) | 1728 | WP_014569367.1 | phospho-sugar mutase | - |
| GM657_RS04415 (GM657_04605) | - | 926747..927394 (+) | 648 | WP_014569368.1 | YfbR-like 5'-deoxynucleotidase | - |
| GM657_RS04420 (GM657_04610) | uvrB | 927665..929680 (+) | 2016 | WP_005688715.1 | excinuclease ABC subunit UvrB | - |
| GM657_RS04425 (GM657_04615) | uvrA | 929861..932755 (+) | 2895 | WP_014569369.1 | excinuclease ABC subunit UvrA | - |
| GM657_RS04430 (GM657_04620) | - | 932957..933496 (+) | 540 | WP_014569370.1 | HdeD family acid-resistance protein | - |
Sequence
Protein
Download Length: 413 a.a. Molecular weight: 44472.12 Da Isoelectric Point: 7.2504
>NTDB_id=403832 GM657_RS04255 WP_014569352.1 892811..894052(+) (cinA) [Lacticaseibacillus rhamnosus GG strain JL-1]
MQAEIIAIGTEILMGQITNTNGAYMAKQLATLGIASYHQQVVGDNAKRLADAISLAEQRSDIVILIGGLGPTPDDLTKQT
LAAHLNLPLVEDADAMAKLAARVKQQQRPMTPNNRLQAMYPQGAIVLANRVGLAVGAWVEQRQHAYVLLPGPPKEFVPMV
DHELLPRLAKYSGHQEVLESRVMRFFGIGESQLVTDLSDLIANQTNPTLATYIKDHEVTVRVTASGKTQAEAAAKLEPMI
GIIMDREGRYFYGYGDDNSLAQELVKALAASDKQISAAESLTAGAFQAALGDVPGVSAYFKGGFVTYALATKAAFLNIDA
RQLSEHGVVSEFTAKAMAEHARQRAAADIAVSFTGVAGPDKLEGQPAGTVWIGLARLGEKPIAQVYHFPGGRNDVRKRAV
MTGMMMVLKRLRE
MQAEIIAIGTEILMGQITNTNGAYMAKQLATLGIASYHQQVVGDNAKRLADAISLAEQRSDIVILIGGLGPTPDDLTKQT
LAAHLNLPLVEDADAMAKLAARVKQQQRPMTPNNRLQAMYPQGAIVLANRVGLAVGAWVEQRQHAYVLLPGPPKEFVPMV
DHELLPRLAKYSGHQEVLESRVMRFFGIGESQLVTDLSDLIANQTNPTLATYIKDHEVTVRVTASGKTQAEAAAKLEPMI
GIIMDREGRYFYGYGDDNSLAQELVKALAASDKQISAAESLTAGAFQAALGDVPGVSAYFKGGFVTYALATKAAFLNIDA
RQLSEHGVVSEFTAKAMAEHARQRAAADIAVSFTGVAGPDKLEGQPAGTVWIGLARLGEKPIAQVYHFPGGRNDVRKRAV
MTGMMMVLKRLRE
Nucleotide
Download Length: 1242 bp
>NTDB_id=403832 GM657_RS04255 WP_014569352.1 892811..894052(+) (cinA) [Lacticaseibacillus rhamnosus GG strain JL-1]
ATGCAAGCAGAAATTATTGCTATCGGAACGGAAATTCTGATGGGACAAATTACAAATACAAATGGCGCGTATATGGCTAA
ACAACTGGCTACATTAGGTATTGCGAGCTATCATCAACAGGTTGTTGGGGATAATGCAAAACGACTGGCTGACGCGATAA
GTTTGGCGGAACAACGCAGTGATATCGTTATTTTGATTGGTGGTTTAGGACCAACACCGGATGATTTAACGAAGCAAACC
CTAGCCGCACACCTGAATTTACCCTTGGTGGAAGACGCTGACGCTATGGCCAAGTTGGCTGCGCGGGTTAAACAACAGCA
ACGTCCAATGACACCCAATAATCGCCTGCAAGCGATGTATCCCCAAGGCGCAATCGTATTGGCCAATCGTGTCGGGTTGG
CGGTCGGCGCATGGGTTGAGCAGCGCCAACACGCCTATGTTTTATTGCCGGGACCACCTAAAGAGTTTGTGCCGATGGTT
GATCATGAACTGTTGCCACGACTGGCAAAATATAGCGGGCATCAAGAAGTTTTGGAAAGTCGCGTGATGCGTTTCTTTGG
TATCGGCGAATCGCAACTTGTGACAGACTTAAGTGATTTAATTGCCAACCAGACGAATCCGACACTTGCAACTTATATAA
AAGATCATGAGGTGACAGTTCGGGTAACTGCGAGTGGCAAAACACAAGCAGAAGCCGCGGCGAAACTTGAGCCAATGATC
GGCATCATTATGGATCGTGAAGGTCGCTACTTTTACGGCTACGGTGACGATAACAGTCTTGCCCAGGAATTAGTCAAAGC
ATTGGCGGCTAGTGATAAGCAAATTAGTGCCGCTGAAAGTCTGACTGCAGGTGCATTTCAAGCGGCATTGGGAGACGTTC
CGGGAGTCTCGGCTTATTTCAAAGGCGGCTTCGTTACGTACGCTTTAGCGACAAAAGCTGCATTTTTAAATATTGATGCC
CGTCAGCTATCAGAACATGGTGTGGTGAGTGAATTTACTGCCAAAGCAATGGCAGAGCATGCTCGTCAACGAGCGGCGGC
AGACATTGCCGTTAGTTTTACCGGAGTTGCCGGTCCTGACAAGCTGGAAGGACAGCCAGCCGGCACCGTCTGGATTGGTT
TGGCGCGGTTAGGAGAGAAACCAATAGCACAAGTTTATCATTTTCCGGGTGGGCGAAATGACGTCCGCAAGCGCGCCGTT
ATGACGGGGATGATGATGGTGTTGAAGCGTTTACGCGAATAA
ATGCAAGCAGAAATTATTGCTATCGGAACGGAAATTCTGATGGGACAAATTACAAATACAAATGGCGCGTATATGGCTAA
ACAACTGGCTACATTAGGTATTGCGAGCTATCATCAACAGGTTGTTGGGGATAATGCAAAACGACTGGCTGACGCGATAA
GTTTGGCGGAACAACGCAGTGATATCGTTATTTTGATTGGTGGTTTAGGACCAACACCGGATGATTTAACGAAGCAAACC
CTAGCCGCACACCTGAATTTACCCTTGGTGGAAGACGCTGACGCTATGGCCAAGTTGGCTGCGCGGGTTAAACAACAGCA
ACGTCCAATGACACCCAATAATCGCCTGCAAGCGATGTATCCCCAAGGCGCAATCGTATTGGCCAATCGTGTCGGGTTGG
CGGTCGGCGCATGGGTTGAGCAGCGCCAACACGCCTATGTTTTATTGCCGGGACCACCTAAAGAGTTTGTGCCGATGGTT
GATCATGAACTGTTGCCACGACTGGCAAAATATAGCGGGCATCAAGAAGTTTTGGAAAGTCGCGTGATGCGTTTCTTTGG
TATCGGCGAATCGCAACTTGTGACAGACTTAAGTGATTTAATTGCCAACCAGACGAATCCGACACTTGCAACTTATATAA
AAGATCATGAGGTGACAGTTCGGGTAACTGCGAGTGGCAAAACACAAGCAGAAGCCGCGGCGAAACTTGAGCCAATGATC
GGCATCATTATGGATCGTGAAGGTCGCTACTTTTACGGCTACGGTGACGATAACAGTCTTGCCCAGGAATTAGTCAAAGC
ATTGGCGGCTAGTGATAAGCAAATTAGTGCCGCTGAAAGTCTGACTGCAGGTGCATTTCAAGCGGCATTGGGAGACGTTC
CGGGAGTCTCGGCTTATTTCAAAGGCGGCTTCGTTACGTACGCTTTAGCGACAAAAGCTGCATTTTTAAATATTGATGCC
CGTCAGCTATCAGAACATGGTGTGGTGAGTGAATTTACTGCCAAAGCAATGGCAGAGCATGCTCGTCAACGAGCGGCGGC
AGACATTGCCGTTAGTTTTACCGGAGTTGCCGGTCCTGACAAGCTGGAAGGACAGCCAGCCGGCACCGTCTGGATTGGTT
TGGCGCGGTTAGGAGAGAAACCAATAGCACAAGTTTATCATTTTCCGGGTGGGCGAAATGACGTCCGCAAGCGCGCCGTT
ATGACGGGGATGATGATGGTGTTGAAGCGTTTACGCGAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| cinA | Streptococcus mitis SK321 |
52.019 |
100 |
0.53 |
| cinA | Streptococcus mitis NCTC 12261 |
52.019 |
100 |
0.53 |
| cinA | Streptococcus pneumoniae TIGR4 |
51.544 |
100 |
0.525 |
| cinA | Streptococcus pneumoniae R6 |
51.069 |
100 |
0.521 |
| cinA | Streptococcus pneumoniae Rx1 |
51.069 |
100 |
0.521 |
| cinA | Streptococcus mutans UA159 |
51.442 |
100 |
0.518 |
| cinA | Streptococcus pneumoniae D39 |
50.831 |
100 |
0.518 |
| cinA | Bacillus subtilis subsp. subtilis str. 168 |
44.66 |
99.758 |
0.446 |
| cinA | Streptococcus suis isolate S10 |
42.593 |
91.525 |
0.39 |