Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   GL187_RS04425 Genome accession   NZ_CP046379
Coordinates   870896..871546 (+) Length   216 a.a.
NCBI ID   WP_050259603.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 563     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 865896..876546
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GL187_RS04380 (GL187_04465) - 866378..866593 (+) 216 WP_001232082.1 YozE family protein -
  GL187_RS04385 (GL187_04470) - 866679..867647 (+) 969 WP_000658183.1 PhoH family protein -
  GL187_RS04395 (GL187_04480) - 867840..868340 (+) 501 WP_000566988.1 GNAT family N-acetyltransferase -
  GL187_RS04400 (GL187_04485) - 868343..868669 (+) 327 Protein_880 TfoX/Sxy family protein -
  GL187_RS11165 ald 868970..870081 (-) 1112 Protein_881 alanine dehydrogenase -
  GL187_RS04420 (GL187_04505) - 870259..870828 (+) 570 WP_000443770.1 GNAT family N-acetyltransferase -
  GL187_RS04425 (GL187_04510) comEA/celA/cilE 870896..871546 (+) 651 WP_050259603.1 helix-hairpin-helix domain-containing protein Machinery gene
  GL187_RS04430 (GL187_04515) comEC/celB 871530..873770 (+) 2241 WP_050259602.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  GL187_RS04435 (GL187_04520) - 873949..874137 (+) 189 WP_001809102.1 hypothetical protein -
  GL187_RS04440 (GL187_04525) - 874169..874756 (+) 588 WP_050259601.1 ATP-binding cassette domain-containing protein -
  GL187_RS04445 (GL187_04530) - 874760..875944 (+) 1185 WP_083979551.1 hypothetical protein -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 23280.65 Da        Isoelectric Point: 5.2344

>NTDB_id=403675 GL187_RS04425 WP_050259603.1 870896..871546(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain 563]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDLVSEKEVNKEEKEEPLEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGFGTASSISKEKKVNINKA
SLEELKQVKGLGGKRAQDIIDHRETNGKFKSVDELKTVSGIGAKTIEKLKDYVTVD

Nucleotide


Download         Length: 651 bp        

>NTDB_id=403675 GL187_RS04425 WP_050259603.1 870896..871546(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain 563]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGAGGATT
TTTCCTGCTAAAACCAGCTCCACAAACACCTGTCAAAGAGACGAATTTGCAGGCTGAAGTCGCAGCTGTTTCCAAGGATT
TGGTATCCGAAAAGGAAGTGAACAAGGAAGAAAAGGAAGAACCCCTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGCCAACAGACTGGTTTTGGGACAGCTTCTTCAATAAGCAAGGAAAAGAAGGTCAATATCAATAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGTGCTCAGGATATTATCGACCATCGTGAAACAAATGG
CAAGTTCAAGTCAGTAGACGAACTCAAGACAGTCTCTGGCATTGGTGCTAAGACCATAGAAAAGCTAAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(76-126)

Helix-hairpin-helix motif (HHH_3)

(151-214)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae Rx1

97.685

100

0.977
  comEA/celA/cilE Streptococcus pneumoniae D39

97.685

100

0.977
  comEA/celA/cilE Streptococcus pneumoniae R6

97.685

100

0.977
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

95.37

100

0.954
  comEA/celA/cilE Streptococcus mitis NCTC 12261

95.37

100

0.954
  comEA/celA/cilE Streptococcus mitis SK321

89.352

100

0.894
  comEA Lactococcus lactis subsp. cremoris KW2

43.172

100

0.454
  comEA Bacillus subtilis subsp. subtilis str. 168

41.579

87.963

0.366

Multiple sequence alignment