Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   GL185_RS09115 Genome accession   NZ_CP046357
Coordinates   1808285..1809541 (+) Length   418 a.a.
NCBI ID   WP_000642706.1    Uniprot ID   A0A098Z3K2
Organism   Streptococcus pneumoniae strain 525     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1803285..1814541
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GL185_RS09085 (GL185_09240) - 1803914..1804084 (-) 171 WP_000742180.1 PhrA family quorum-sensing system peptide -
  GL185_RS09090 (GL185_09245) - 1804273..1805136 (+) 864 WP_024477662.1 helix-turn-helix transcriptional regulator -
  GL185_RS09095 (GL185_09250) comM 1805519..1806139 (+) 621 WP_000839909.1 hypothetical protein Regulator
  GL185_RS09100 (GL185_09255) tsaE 1806225..1806668 (+) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  GL185_RS09105 (GL185_09260) - 1806658..1807176 (+) 519 WP_024477661.1 GNAT family N-acetyltransferase -
  GL185_RS09110 (GL185_09265) - 1807184..1808200 (+) 1017 WP_000239278.1 LCP family protein -
  GL185_RS09115 (GL185_09270) cinA 1808285..1809541 (+) 1257 WP_000642706.1 competence/damage-inducible protein A Machinery gene
  GL185_RS09120 (GL185_09275) recA 1809596..1810762 (+) 1167 WP_001085463.1 recombinase RecA Machinery gene
  GL185_RS09125 (GL185_09280) - 1811069..1812439 (+) 1371 WP_001036270.1 MATE family efflux transporter -
  GL185_RS09130 (GL185_09285) lytA 1812815..1813771 (+) 957 WP_000405234.1 N-acetylmuramoyl-L-alanine amidase LytA -
  GL185_RS09135 (GL185_09290) - 1814143..1814304 (+) 162 WP_000289348.1 helix-turn-helix transcriptional regulator -
  GL185_RS09140 (GL185_09295) - 1814291..1814497 (+) 207 WP_000366088.1 hypothetical protein -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45062.40 Da        Isoelectric Point: 4.5211

>NTDB_id=403208 GL185_RS09115 WP_000642706.1 1808285..1809541(+) (cinA) [Streptococcus pneumoniae strain 525]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQT
LAKFLGKALVFDPQAQEKLDIFFALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLRLSTKASSQEEANQALDILENQI
LDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQGKTIAAAESLTAGLFQATVANFSGVSSIFEGGFVTYSLEEKSRML
DIPAKNLEEHGVVSEFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIGGRSRADVR
HIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=403208 GL185_RS09115 WP_000642706.1 1808285..1809541(+) (cinA) [Streptococcus pneumoniae strain 525]
ATGAAAGCAGAAATCATTGCTGTTGGAACAGAGATTTTGACAGGACAGATTGTCAACACCAATGCCCAGTTTTTGTCGGA
AAAACTAGCTGAGATTGGGGTAGATGTATATTTTCAGACGGCTGTAGGAGACAATGAAGTTCGTCTCTTGTCTTTGCTTG
AGATTGCCAGTCAACGTAGCAGTCTGGTGATTTTGACAGGCGGTTTGGGGCCAACTGAGGACGACCTAACCAAACAAACC
CTAGCTAAATTTTTAGGGAAAGCATTAGTCTTTGATCCTCAGGCTCAGGAGAAGTTGGATATCTTTTTTGCCCTGCGACC
AGACTATGCCCGAACACCAAATAACGAAAGACAAGCTCAAATTGTAGAAGGAGCGATTCCACTGCCAAACGAAACAGGAC
TGGCTGTTGGAGGAAAATTAGAAGTAGACGGAGTGACCTATGTCGTCCTTCCAGGTCCGCCAAGTGAATTGAAACCCATG
GTCTTAAACCAACTTCTACCCAAGTTGATGACAGGGAGCAAGCTGTATTCCCGAGTTCTTCGTTTCTTTGGGATTGGCGA
GAGCCAGTTGGTTACGATTTTGGCTGATTTAATTGATAATCAGATCGATCCTACCTTGGCCCCTTATGCCAAGACAGGAG
AAGTCACTCTACGTCTGTCAACAAAGGCTAGCAGTCAAGAAGAGGCGAATCAAGCGCTGGATATCTTGGAAAATCAAATC
TTGGACTGCCAGACTTTCGAAGGAATTTCTTTACGAGACTTTTGCTATGGTTATGGGGAAGAAACTAGTTTAGCCAGCAT
TGTGGTAGAAGAACTGAAAAGGCAAGGGAAAACCATCGCGGCTGCAGAGAGTTTGACGGCAGGTCTTTTCCAAGCTACCG
TGGCGAATTTTTCTGGAGTTTCAAGTATATTTGAGGGTGGTTTTGTGACCTATAGCTTGGAGGAAAAATCAAGGATGTTG
GATATTCCTGCCAAGAATTTGGAAGAACATGGTGTGGTGTCTGAATTTACAGCTCAGAAGATGGCTGAGCAGGCACGAAG
CAAGACCCAGTCTGATTTTGGAATTAGTTTGACTGGAGTGGCAGGACCAGATAGCCTAGAAGGACACCCAGTTGGGACAG
TCTTCATAGGCTTGGCGCAAGATCAAGGAACTGAGGTTATCAAGGTTAATATTGGAGGCAGAAGCCGAGCAGATGTACGT
CACATTGCGGTTATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(262-414)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A098Z3K2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus pneumoniae Rx1

99.761

100

0.998
  cinA Streptococcus pneumoniae R6

99.761

100

0.998
  cinA Streptococcus pneumoniae TIGR4

99.522

100

0.995
  cinA Streptococcus pneumoniae D39

99.522

100

0.995
  cinA Streptococcus mitis SK321

93.541

100

0.935
  cinA Streptococcus mitis NCTC 12261

93.301

100

0.933
  cinA Streptococcus mutans UA159

70.813

100

0.708
  cinA Streptococcus suis isolate S10

55.048

99.522

0.548
  cinA Bacillus subtilis subsp. subtilis str. 168

45.455

100

0.455

Multiple sequence alignment