Detailed information NTG0403028

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: GL183_RS01990
• Genome accession: NZ_CP046355
• Coordinates: 364087..365154 (+)
• Length: 355 a.a.
• NCBI ID: WP_000159556.1
• Uniprot ID: A0A0B7LLF7
• Organism: Streptococcus pneumoniae strain 475
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 359087..370154

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GL183_RS01975 (GL183_01990)	amiA3	359610..361589 (+)	1980	WP_000742232.1	peptide ABC transporter substrate-binding protein	Regulator
GL183_RS01980 (GL183_01995)	amiC	361656..363152 (+)	1497	WP_000759903.1	ABC transporter permease	Regulator
GL183_RS01985 (GL183_02000)	amiD	363152..364078 (+)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
GL183_RS01990 (GL183_02005)	amiE	364087..365154 (+)	1068	WP_000159556.1	ABC transporter ATP-binding protein	Regulator
GL183_RS01995 (GL183_02010)	amiF	365165..366091 (+)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
GL183_RS02000 (GL183_02015)	-	366581..367312 (+)	732	WP_162489596.1	ABC transporter substrate-binding protein	-
GL183_RS02005 (GL183_02020)	-	367324..368217 (+)	894	WP_024477718.1	ABC transporter permease	-
GL183_RS02010 (GL183_02025)	-	368230..369033 (+)	804	WP_024477717.1	ATP-binding cassette domain-containing protein	-
GL183_RS02015 (GL183_02030)	treR	369066..369776 (-)	711	WP_000760673.1	trehalose operon repressor	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39504.11 Da
• Isoelectric Point: 4.8764

>NTDB_id=403028 GL183_RS01990 WP_000159556.1 364087..365154(+) (amiE) [Streptococcus pneumoniae strain 475]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGELYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=403028 GL183_RS01990 WP_000159556.1 364087..365154(+) (amiE) [Streptococcus pneumoniae strain 475]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTGACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGAACTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

3D structure

• AlphaFold DB: A0A0B7LLF7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.451	100	0.885
amiE	Streptococcus thermophilus LMG 18311	86.479	100	0.865
amiE	Streptococcus thermophilus LMD-9	86.479	100	0.865
oppD	Streptococcus mutans UA159	54.545	99.155	0.541