Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   GJS33_RS09390 Genome accession   NZ_CP046041
Coordinates   1985015..1986286 (-) Length   423 a.a.
NCBI ID   WP_154299186.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain AZ-45470     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1980015..1991286
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GJS33_RS09365 (GJS33_09365) - 1981905..1982204 (-) 300 WP_012516437.1 DUF1292 domain-containing protein -
  GJS33_RS09370 (GJS33_09370) ruvX 1982214..1982633 (-) 420 WP_015898660.1 Holliday junction resolvase RuvX -
  GJS33_RS09375 (GJS33_09375) - 1982630..1982899 (-) 270 WP_012516439.1 IreB family regulatory phosphoprotein -
  GJS33_RS09380 (GJS33_09380) spx 1983011..1983409 (-) 399 WP_012516440.1 transcriptional regulator Spx -
  GJS33_RS09385 (GJS33_09385) recA 1983785..1984921 (-) 1137 WP_012678688.1 recombinase RecA Machinery gene
  GJS33_RS09390 (GJS33_09390) cinA 1985015..1986286 (-) 1272 WP_154299186.1 competence/damage-inducible protein A Machinery gene
  GJS33_RS09395 (GJS33_09395) - 1986972..1987262 (-) 291 WP_012516443.1 hypothetical protein -
  GJS33_RS09400 (GJS33_09400) - 1987256..1987828 (-) 573 WP_111692841.1 phospholipase -
  GJS33_RS09405 (GJS33_09405) - 1988125..1988970 (+) 846 WP_012678692.1 helix-turn-helix domain-containing protein -
  GJS33_RS09410 (GJS33_09410) - 1989414..1989965 (-) 552 WP_126437117.1 DNA-3-methyladenine glycosylase I -
  GJS33_RS09415 (GJS33_09415) ruvA 1989975..1990571 (-) 597 WP_115251409.1 Holliday junction branch migration protein RuvA -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45912.58 Da        Isoelectric Point: 5.3452

>NTDB_id=400554 GJS33_RS09390 WP_154299186.1 1985015..1986286(-) (cinA) [Streptococcus equi subsp. zooepidemicus strain AZ-45470]
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVIDIASQRSDLVILCGGLGPTDDDLTKQT
LAKYLGKALVFDEQAGQKLDAFFAHRKQAARTPNNQRQAQLIEGSIALQNQTGLAVGGLITVDRVTYVVLPGPPSELKPM
VKNELVPLLSASHASLYSRVLRFFGIGESQLVTALEDLIKHQTDPTIAPYAKTGEVTLRLSTKADNQALADERLNRLEAQ
LLSIRTVDNQPLRRLLYGYGEDNSLARETFELLKRSGKTITAAESLTAGLFQAQLTDFAGASQVFNGGFITYSIEEKAKM
LGIPLVELQRHGVVSSFTAEQMAAQARCLTDSDIGIGLTGVAGPEELEEQPAGTVFIGLATKNKVESLKVVIGGRSRLDV
RYIATLYAFNMARKTLLKSENLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=400554 GJS33_RS09390 WP_154299186.1 1985015..1986286(-) (cinA) [Streptococcus equi subsp. zooepidemicus strain AZ-45470]
ATGAAAGCTGAACTCATTGCAGTGGGAACCGAGATTCTGACTGGTCAGATTGTGAATACCAATGCTCAATTTTTATCAGA
AAAAATGGCGGAGCTTGGTATTGATGTTTATTTTCAAACAGCTGTAGGAGATAATGAAGAGCGTTTGCTTTCTGTTATTG
ATATTGCTAGCCAGCGAAGTGATTTAGTGATTTTATGTGGTGGTCTTGGTCCAACAGATGATGATCTAACGAAGCAGACC
TTAGCTAAGTATCTGGGAAAAGCTTTGGTCTTTGATGAGCAGGCAGGTCAAAAATTAGATGCTTTTTTTGCACATCGTAA
GCAGGCTGCTAGGACACCAAATAACCAACGTCAGGCGCAGCTGATTGAAGGCTCTATTGCTTTGCAAAATCAAACAGGAC
TTGCAGTAGGTGGGTTAATAACTGTAGATAGGGTAACCTATGTTGTCTTACCAGGGCCTCCAAGTGAGCTAAAGCCTATG
GTAAAAAATGAGCTGGTGCCCCTTCTTTCAGCTAGTCATGCCAGTCTATATTCAAGAGTGCTGCGTTTTTTTGGCATTGG
TGAAAGTCAACTGGTGACTGCTCTGGAGGATTTGATTAAGCATCAAACAGATCCTACTATTGCTCCTTATGCAAAGACCG
GCGAGGTAACACTGCGACTATCCACAAAGGCTGACAACCAAGCATTAGCTGATGAAAGGCTGAATCGACTAGAGGCGCAG
CTCTTATCCATAAGAACTGTAGATAATCAACCCTTACGGCGTTTGCTTTATGGCTATGGGGAGGATAATTCCTTGGCGCG
TGAGACCTTTGAGTTATTGAAGCGAAGTGGTAAGACGATAACAGCAGCTGAAAGCTTAACAGCAGGACTGTTTCAGGCTC
AGCTAACTGATTTTGCGGGAGCTTCACAGGTGTTTAACGGTGGCTTTATCACCTACAGCATTGAAGAAAAAGCAAAAATG
CTTGGCATTCCATTGGTTGAGCTACAAAGGCATGGTGTTGTGAGCTCTTTTACAGCTGAACAAATGGCTGCGCAGGCACG
TTGCTTGACCGATTCAGATATCGGTATTGGTCTAACAGGTGTTGCTGGTCCAGAGGAACTCGAGGAGCAGCCAGCAGGAA
CAGTTTTCATTGGCCTTGCCACTAAGAATAAGGTAGAATCTCTTAAAGTTGTCATAGGAGGTCGCAGCCGTTTGGACGTG
CGGTACATTGCTACTCTGTACGCTTTTAATATGGCTCGTAAAACTTTATTAAAATCAGAGAATTTGCTATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-241)

Competence-damaged protein (CinA)

(263-416)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

69.976

100

0.7
  cinA Streptococcus mitis NCTC 12261

70.264

98.582

0.693
  cinA Streptococcus mitis SK321

70.024

98.582

0.69
  cinA Streptococcus pneumoniae TIGR4

69.305

98.582

0.683
  cinA Streptococcus pneumoniae Rx1

69.305

98.582

0.683
  cinA Streptococcus pneumoniae R6

69.305

98.582

0.683
  cinA Streptococcus pneumoniae D39

69.065

98.582

0.681
  cinA Streptococcus suis isolate S10

53.938

99.054

0.534
  cinA Bacillus subtilis subsp. subtilis str. 168

47.129

98.818

0.466

Multiple sequence alignment