Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   GIO26_RS07640 Genome accession   NZ_CP046022
Coordinates   1621267..1622511 (+) Length   414 a.a.
NCBI ID   WP_002424926.1    Uniprot ID   -
Organism   Enterococcus faecalis strain BFF1B1     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1616267..1627511
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GIO26_RS07615 - 1617256..1618047 (-) 792 WP_002367471.1 hypothetical protein -
  GIO26_RS07620 - 1618211..1618594 (+) 384 WP_002365398.1 YccF domain-containing protein -
  GIO26_RS07625 - 1618683..1619108 (+) 426 WP_207578874.1 Rrf2 family transcriptional regulator -
  GIO26_RS07630 - 1619167..1619796 (+) 630 WP_207463144.1 NAD(P)-dependent oxidoreductase -
  GIO26_RS07635 - 1619876..1621075 (-) 1200 WP_073438193.1 hypothetical protein -
  GIO26_RS07640 cinA 1621267..1622511 (+) 1245 WP_002424926.1 competence/damage-inducible protein A Machinery gene
  GIO26_RS07645 recA 1622625..1623671 (+) 1047 WP_002354860.1 recombinase RecA Machinery gene
  GIO26_RS07650 - 1623831..1624136 (+) 306 WP_010821936.1 hypothetical protein -
  GIO26_RS07655 - 1624141..1625391 (+) 1251 WP_083578715.1 PTS transporter subunit EIIC -
  GIO26_RS07660 - 1625411..1625752 (+) 342 WP_002359005.1 PTS lactose/cellobiose transporter subunit IIA -
  GIO26_RS07665 - 1625734..1627197 (+) 1464 WP_002407853.1 glycoside hydrolase family 1 protein -

Sequence

Protein


Download         Length: 414 a.a.        Molecular weight: 45183.25 Da        Isoelectric Point: 4.6698

>NTDB_id=400236 GIO26_RS07640 WP_002424926.1 1621267..1622511(+) (cinA) [Enterococcus faecalis strain BFF1B1]
MKAEIIAVGTELLLGQVVNTNATFLSEELAALGIDVYYQTVVGDNGGRLETLLTEAEQRSDLIVLCGGLGPTEDDLTKQV
VAQHLHKSLVEDQEGLNRLHQFFQQSKRPMTENNLRQVLAIEGGQVLQNPTGLAVGSFVTEGTTSYLLLPGPPNELIPMF
QQAARPLLIDAFPQEEQLISRVLRFYGIGESQLVTEIQSLIAHQTNPTIAPYAKPNEVTLRLTVKTKDLVAGEELLTATE
EKVLAKVGDYFYGYGDDNSLAKVTVDLLLQNGQTVTAAESLTAGLFQSTLGEIAGASKIFKGGFVTYSQETKENFLGISH
ELLEEHGTVSEACAKEMAEKARQLAKSNYGLSFTGVAGDSIEGQPTGTVWIGLAEEGQPTVAECFHFNRDRNYIRQSAVM
RGLDLLRRRIINKK

Nucleotide


Download         Length: 1245 bp        

>NTDB_id=400236 GIO26_RS07640 WP_002424926.1 1621267..1622511(+) (cinA) [Enterococcus faecalis strain BFF1B1]
ATGAAAGCAGAAATCATTGCAGTCGGAACAGAGTTATTACTGGGACAAGTAGTGAATACCAACGCCACCTTTTTATCAGA
AGAGTTAGCTGCGCTAGGCATCGATGTTTACTATCAGACCGTTGTTGGTGATAACGGCGGCCGCTTAGAAACGCTACTAA
CAGAAGCAGAACAAAGAAGTGATTTAATTGTCCTTTGTGGAGGGCTAGGACCTACAGAAGACGATTTAACCAAGCAAGTT
GTCGCACAACATCTCCATAAATCATTAGTAGAAGATCAAGAAGGATTGAACCGCTTACACCAGTTTTTCCAACAGTCTAA
GCGGCCAATGACGGAAAATAATCTACGACAAGTGTTAGCCATTGAAGGTGGACAAGTTCTTCAAAACCCGACAGGATTAG
CGGTTGGTTCTTTCGTAACAGAAGGGACAACAAGCTATTTGCTCTTACCAGGGCCGCCCAATGAATTAATTCCGATGTTT
CAACAAGCGGCACGACCTTTATTGATTGATGCGTTTCCACAAGAAGAACAATTGATTTCGAGAGTCTTGCGTTTTTATGG
CATTGGTGAATCCCAGCTGGTGACCGAGATTCAATCGTTGATTGCGCACCAAACGAATCCAACCATTGCGCCTTATGCTA
AGCCTAATGAAGTGACACTTCGTTTAACAGTTAAAACAAAAGACTTAGTAGCTGGCGAAGAATTATTAACAGCGACGGAA
GAAAAGGTTTTAGCTAAAGTGGGAGACTATTTTTATGGGTATGGGGATGACAATAGTTTAGCCAAGGTAACAGTGGATTT
GTTATTACAAAACGGACAAACCGTCACGGCTGCTGAGAGCCTCACCGCTGGCCTATTCCAAAGTACACTGGGGGAAATTG
CGGGCGCTTCGAAGATTTTTAAGGGAGGCTTCGTGACGTATTCGCAAGAAACAAAAGAGAACTTTTTAGGAATTTCTCAT
GAACTTTTAGAAGAACATGGCACGGTAAGTGAAGCGTGTGCCAAAGAAATGGCAGAGAAAGCGCGTCAGTTAGCTAAATC
TAACTATGGTTTATCATTTACTGGGGTCGCTGGTGACTCAATCGAAGGTCAACCGACAGGCACTGTTTGGATTGGGCTGG
CGGAAGAAGGCCAACCAACCGTTGCAGAATGTTTCCATTTTAACCGTGACCGAAATTATATTAGACAGAGTGCGGTTATG
CGAGGGTTAGATCTTTTGCGGCGCCGAATCATTAATAAAAAATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(258-409)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-168)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

52.632

100

0.531
  cinA Streptococcus mitis SK321

51.773

100

0.529
  cinA Streptococcus mitis NCTC 12261

51.537

100

0.527
  cinA Streptococcus pneumoniae TIGR4

50.827

100

0.519
  cinA Streptococcus pneumoniae D39

50.591

100

0.517
  cinA Streptococcus pneumoniae R6

50.355

100

0.514
  cinA Streptococcus pneumoniae Rx1

50.355

100

0.514
  cinA Bacillus subtilis subsp. subtilis str. 168

48.522

98.068

0.476
  cinA Streptococcus suis isolate S10

44.282

99.275

0.44

Multiple sequence alignment