Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   GFB65_RS11990 Genome accession   NZ_CP045598
Coordinates   2531224..2532468 (-) Length   414 a.a.
NCBI ID   WP_323746137.1    Uniprot ID   -
Organism   Enterococcus faecalis strain TK-P4B     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2526224..2537468
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GFB65_RS11970 (GFB65_12645) - 2526694..2527080 (-) 387 WP_002359008.1 RicAFT regulatory complex protein RicA family protein -
  GFB65_RS11975 (GFB65_12650) - 2527154..2527951 (-) 798 WP_002354864.1 TIGR00282 family metallophosphoesterase -
  GFB65_RS11980 (GFB65_12655) rny 2528111..2529667 (-) 1557 WP_002354863.1 ribonuclease Y -
  GFB65_RS11985 (GFB65_12665) recA 2530064..2531110 (-) 1047 WP_002354860.1 recombinase RecA Machinery gene
  GFB65_RS11990 (GFB65_12670) cinA 2531224..2532468 (-) 1245 WP_323746137.1 competence/damage-inducible protein A Machinery gene
  GFB65_RS11995 (GFB65_12675) - 2532660..2533859 (+) 1200 WP_002370127.1 hypothetical protein -
  GFB65_RS12000 (GFB65_12680) - 2533939..2534568 (-) 630 WP_002354854.1 NAD(P)-dependent oxidoreductase -
  GFB65_RS12005 (GFB65_12685) - 2534627..2535052 (-) 426 WP_002383201.1 Rrf2 family transcriptional regulator -
  GFB65_RS12010 (GFB65_12690) - 2535141..2535524 (-) 384 WP_002354850.1 YccF domain-containing protein -
  GFB65_RS12015 (GFB65_12695) - 2535688..2536479 (+) 792 WP_002354848.1 hypothetical protein -

Sequence

Protein


Download         Length: 414 a.a.        Molecular weight: 45197.28 Da        Isoelectric Point: 4.6698

>NTDB_id=395537 GFB65_RS11990 WP_323746137.1 2531224..2532468(-) (cinA) [Enterococcus faecalis strain TK-P4B]
MKAEIIAVGTELLLGQVVNTNATFLSEELAALGIDVYYQTVVGDNGGRLETLLTEAEQRSDLIVLCGGLGPTEDDLTKQV
VAQHLHKSLVEDQEGLNRLHQFFQQSKRPMTENNLRQVLAIEGGQVLQNPTGLAVGSFVTEGTTSYLLLPGPPNELIPMF
QQAARSLLIDAFPQEEQLISRVLRFYGIGESQLVTEIQSLIAHQTNPTIAPYAKPNEVTLRLTVKTKDLVAGEELLTATE
EKVLAKVGDYFYGYGDDNSLAKVTVDLLLQNGQTVTAAESLTAGLFQSTLGEIAGASKIFKGGFVTYSQETKENFLGISH
ELLEEHGTVSEACAKEMAEKARQLAKSNYGLSFTGVAGDPLEGQPTGTVWIGLAEEGQPTVAECFHFNRDRNYIRQSAIM
RGLDLLRRRIINKK

Nucleotide


Download         Length: 1245 bp        

>NTDB_id=395537 GFB65_RS11990 WP_323746137.1 2531224..2532468(-) (cinA) [Enterococcus faecalis strain TK-P4B]
ATGAAAGCAGAAATCATTGCAGTCGGAACAGAGTTATTACTTGGACAAGTAGTGAATACCAACGCCACCTTTTTATCAGA
AGAGTTAGCTGCGCTAGGCATCGATGTTTACTATCAGACCGTTGTTGGCGATAACGGCGGCCGCTTAGAAACGCTACTAA
CAGAAGCAGAACAAAGAAGTGATTTAATTGTCCTTTGTGGAGGGCTAGGACCTACAGAAGACGATTTAACCAAGCAAGTT
GTCGCACAACATCTTCATAAATCATTAGTAGAAGATCAAGAAGGATTGAACCGCTTGCACCAGTTTTTCCAACAGTCTAA
GCGGCCAATGACGGAAAATAATCTACGACAAGTGTTAGCCATTGAAGGTGGACAAGTTCTTCAAAACCCGACAGGATTAG
CGGTTGGTTCTTTCGTAACAGAAGGCACAACAAGCTATTTGCTCTTACCAGGGCCGCCCAATGAATTAATTCCGATGTTT
CAACAAGCGGCACGATCTTTATTGATTGATGCGTTTCCACAAGAAGAACAATTGATTTCGAGAGTCTTGCGTTTTTATGG
CATTGGTGAATCACAGCTGGTGACCGAGATTCAATCGTTGATTGCGCACCAAACGAATCCAACCATTGCGCCTTATGCTA
AGCCTAATGAAGTGACACTTCGTTTAACAGTTAAAACAAAAGACTTAGTAGCCGGCGAAGAATTATTAACAGCGACGGAA
GAAAAGGTTTTAGCTAAAGTGGGAGACTATTTTTATGGGTATGGGGATGACAATAGTTTAGCCAAGGTAACAGTGGATTT
GTTATTACAAAACGGACAAACCGTCACGGCTGCTGAGAGCCTCACCGCTGGCCTATTCCAAAGTACACTGGGGGAAATTG
CGGGTGCTTCGAAGATTTTTAAGGGAGGCTTCGTGACGTATTCGCAAGAAACAAAAGAGAACTTTTTAGGAATTTCTCAT
GAACTTTTAGAAGAACATGGCACGGTAAGTGAAGCGTGTGCCAAAGAAATGGCAGAGAAAGCGCGTCAGTTAGCTAAATC
TAACTATGGTTTATCATTTACTGGGGTCGCTGGTGACCCACTCGAAGGTCAACCGACAGGCACTGTTTGGATTGGGCTGG
CGGAAGAAGGCCAACCAACCGTTGCAGAATGTTTCCATTTTAACCGTGACCGAAATTATATTAGACAGAGTGCGATTATG
CGAGGGTTAGATCTTTTGCGGCGCCGAATCATTAATAAAAAATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(258-409)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-164)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

52.392

100

0.529
  cinA Streptococcus mitis SK321

51.3

100

0.524
  cinA Streptococcus mitis NCTC 12261

51.064

100

0.522
  cinA Streptococcus pneumoniae TIGR4

50.355

100

0.514
  cinA Streptococcus pneumoniae D39

50.118

100

0.512
  cinA Streptococcus pneumoniae R6

49.882

100

0.51
  cinA Streptococcus pneumoniae Rx1

49.882

100

0.51
  cinA Bacillus subtilis subsp. subtilis str. 168

48.276

98.068

0.473
  cinA Streptococcus suis isolate S10

43.796

99.275

0.435

Multiple sequence alignment