Detailed information NTG0395497

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: GFB63_RS09115
• Genome accession: NZ_CP045596
• Coordinates: 1768249..1768956 (+)
• Length: 235 a.a.
• NCBI ID: WP_011681206.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain TK-P3A
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1763249..1773956

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GFB63_RS09085 (GFB63_09335)	-	1763530..1763718 (+)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
GFB63_RS09090 (GFB63_09340)	endA	1763780..1764661 (+)	882	WP_111679622.1	DNA/RNA non-specific endonuclease	Machinery gene
GFB63_RS09095 (GFB63_09345)	-	1764732..1765382 (-)	651	WP_100273221.1	amino acid ABC transporter permease	-
GFB63_RS09100 (GFB63_09350)	-	1765394..1766092 (-)	699	WP_014608374.1	amino acid ABC transporter permease	-
GFB63_RS09105 (GFB63_09355)	-	1766110..1766943 (-)	834	WP_002953142.1	transporter substrate-binding domain-containing protein	-
GFB63_RS09110 (GFB63_09360)	-	1766955..1767722 (-)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
GFB63_RS09115 (GFB63_09365)	vicR	1768249..1768956 (+)	708	WP_011681206.1	response regulator YycF	Regulator
GFB63_RS09120 (GFB63_09370)	vicK	1768949..1770289 (+)	1341	WP_084828862.1	cell wall metabolism sensor histidine kinase VicK	Regulator
GFB63_RS09125 (GFB63_09375)	vicX	1770298..1771107 (+)	810	WP_100262465.1	MBL fold metallo-hydrolase	Regulator
GFB63_RS09130 (GFB63_09380)	-	1771184..1771536 (+)	353	Protein_1762	YbaN family protein	-
GFB63_RS09135 (GFB63_09385)	-	1771588..1772802 (-)	1215	WP_084830670.1	aminoacyltransferase	-
GFB63_RS09140 (GFB63_09390)	yidA	1772804..1773613 (-)	810	WP_193838276.1	sugar-phosphatase	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27058.98 Da
• Isoelectric Point: 5.0130

>NTDB_id=395497 GFB63_RS09115 WP_011681206.1 1768249..1768956(+) (vicR) [Streptococcus thermophilus strain TK-P3A]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAKKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEESSNSGKQEISIGELVIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=395497 GFB63_RS09115 WP_011681206.1 1768249..1768956(+) (vicR) [Streptococcus thermophilus strain TK-P3A]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGGCCTTTGATGGGCGAGAAGCTTTGGAACAATTTGAAGCTAAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAGTTGCCAAGGAAATCCGTAAAACGAGCCACACACCGATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTGACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACGATTGAAACTGCAGTAGAAGAGAGCTCTAACTCTGGCA
AACAAGAAATTTCAATTGGTGAGTTGGTTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCATTTGGCAACTCATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	85.532	100	0.855
micA	Streptococcus pneumoniae Cp1015	80.258	99.149	0.796
covR	Lactococcus lactis subsp. lactis strain DGCC12653	46.32	98.298	0.455
covR	Streptococcus salivarius strain HSISS4	45.299	99.574	0.451
scnR	Streptococcus mutans UA159	38.559	100	0.387