Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   GFB63_RS09120 Genome accession   NZ_CP045596
Coordinates   1768949..1770289 (+) Length   446 a.a.
NCBI ID   WP_084828862.1    Uniprot ID   A0A0E2Q0P2
Organism   Streptococcus thermophilus strain TK-P3A     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1763949..1775289
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GFB63_RS09095 (GFB63_09345) - 1764732..1765382 (-) 651 WP_100273221.1 amino acid ABC transporter permease -
  GFB63_RS09100 (GFB63_09350) - 1765394..1766092 (-) 699 WP_014608374.1 amino acid ABC transporter permease -
  GFB63_RS09105 (GFB63_09355) - 1766110..1766943 (-) 834 WP_002953142.1 transporter substrate-binding domain-containing protein -
  GFB63_RS09110 (GFB63_09360) - 1766955..1767722 (-) 768 WP_011681207.1 amino acid ABC transporter ATP-binding protein -
  GFB63_RS09115 (GFB63_09365) vicR 1768249..1768956 (+) 708 WP_011681206.1 response regulator YycF Regulator
  GFB63_RS09120 (GFB63_09370) vicK 1768949..1770289 (+) 1341 WP_084828862.1 cell wall metabolism sensor histidine kinase VicK Regulator
  GFB63_RS09125 (GFB63_09375) vicX 1770298..1771107 (+) 810 WP_100262465.1 MBL fold metallo-hydrolase Regulator
  GFB63_RS09130 (GFB63_09380) - 1771184..1771536 (+) 353 Protein_1762 YbaN family protein -
  GFB63_RS09135 (GFB63_09385) - 1771588..1772802 (-) 1215 WP_084830670.1 aminoacyltransferase -
  GFB63_RS09140 (GFB63_09390) yidA 1772804..1773613 (-) 810 WP_193838276.1 sugar-phosphatase -
  GFB63_RS09145 (GFB63_09395) - 1773821..1774685 (+) 865 Protein_1765 GNAT family N-acetyltransferase -
  GFB63_RS09150 (GFB63_09400) - 1774777..1775163 (+) 387 WP_002953113.1 DUF1934 domain-containing protein -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50777.01 Da        Isoelectric Point: 5.2465

>NTDB_id=395498 GFB63_RS09120 WP_084828862.1 1768949..1770289(+) (vicK) [Streptococcus thermophilus strain TK-P3A]
MTSIGLNITSFELALLFTLLFVAFYFIFLAYRDYQQVKNIRKLTKRVKSLMAGNYNEKLRIKGDSELLELANSLNDLSDV
FRLTHENLIQEKNRLSSVLSYMSDGVIATNRLGQITMINSTAQRLLNLDRETATQMSILDILDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALNE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLNVEMTNFTAFMTYILNRFGQIKSQETNPGKSYEIIRDYPVNSI
WVEIDTDKMTQVVDNILNNAIKYSPDGGQITVSMKTTDTQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIVKQHNGFIWAKSEYGKGSTFTIVLPYDQDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=395498 GFB63_RS09120 WP_084828862.1 1768949..1770289(+) (vicK) [Streptococcus thermophilus strain TK-P3A]
ATGACTAGTATTGGCTTAAATATTACAAGCTTTGAACTAGCCTTACTCTTTACGCTCCTCTTTGTTGCTTTCTATTTCAT
TTTTCTAGCTTATCGTGATTATCAACAGGTCAAAAATATCCGAAAGTTGACTAAGAGAGTCAAATCCCTTATGGCAGGTA
ATTATAATGAAAAATTACGCATAAAGGGAGATTCAGAGCTTTTAGAGCTAGCTAATAGCTTGAATGATTTGTCGGACGTC
TTTCGTTTGACACATGAAAATCTAATCCAGGAAAAAAACCGCTTATCATCTGTCCTTTCGTACATGAGTGACGGGGTTAT
TGCGACCAATCGCCTTGGTCAGATTACTATGATTAATAGTACTGCCCAACGCTTGTTGAATTTAGATCGCGAAACTGCGA
CTCAGATGTCTATTTTGGATATATTAGATGGTGAGAATCCCTATACCTATAGTGAATTGTTGTCTAAGACACCCGAAATC
CATCTGTCGCGTCGAGATGCTAACGATGAATTTGTGACGCTACGTGTTAATTTTGCATTAATTCGTAAGGAATCTGGTTT
TATTTCAGGTCTGGTAGCCGTTCTTCATGATGCCACTGAGCAGGAAAAAGAAGAGCGCGAACGCCGTCTCTTCGTATCAA
ATGTTAGTCACGAATTGCGGACGCCTTTAACTTCTGTGAAATCCTATCTTGAAGCGCTTGATGATGGTGCTCTCAACGAA
GAGATTGCTCCAAACTTTATCAAAGTTTCTTTAGATGAAACCAACCGCATGATGCGTATGATTTCTGACCTCTTGGCATT
ATCTCGAATTGACAATAAAAGCACACAGCTTAATGTTGAAATGACAAACTTTACAGCCTTTATGACCTATATCTTGAATC
GATTTGGTCAAATTAAGAGTCAAGAAACTAATCCAGGTAAGTCTTATGAAATCATTCGAGATTACCCAGTAAACTCTATT
TGGGTGGAAATTGATACTGATAAGATGACCCAGGTCGTAGATAATATACTTAATAATGCCATCAAGTATTCTCCTGATGG
TGGGCAAATTACAGTATCTATGAAAACGACAGACACTCAGTTGATTGTTTCTATTTCTGACCAAGGTTTAGGAATTCCTA
AAAAAGATTTACCTCTGATTTTTGACCGTTTTTACCGTGTTGATAAGGCCAGAAGTCGTGCTCAGGGTGGAACAGGACTT
GGCTTGTCCATAGCAAAAGAAATTGTTAAACAACATAATGGCTTCATTTGGGCTAAGAGTGAGTATGGTAAGGGGTCAAC
TTTTACAATTGTGCTTCCATATGACCAGGACGCAATGATGGTCGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)

PAS fold (PAS)

(94-197)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

HAMP domain (HAMP)

(37-79)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E2Q0P2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.913

92.825

0.686
  micB Streptococcus pneumoniae Cp1015

66.051

97.085

0.641

Multiple sequence alignment