Detailed information NTG0395480

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: GFB63_RS06030
• Genome accession: NZ_CP045596
• Coordinates: 1170233..1171132 (+)
• Length: 299 a.a.
• NCBI ID: WP_111679231.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain TK-P3A
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 1165233..1176132

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GFB63_RS06010 (GFB63_06180)	trkA	1166369..1167718 (-)	1350	WP_024704181.1	Trk system potassium transporter TrkA	-
GFB63_RS06015 (GFB63_06185)	-	1167978..1168517 (+)	540	WP_372585740.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
GFB63_RS06020 (GFB63_06190)	-	1168828..1169385 (+)	558	WP_111679227.1	ECF transporter S component	-
GFB63_RS06025 (GFB63_06195)	-	1169388..1170038 (+)	651	WP_193838187.1	phosphatase PAP2 family protein	-
GFB63_RS06030 (GFB63_06200)	comR	1170233..1171132 (+)	900	WP_111679231.1	helix-turn-helix domain-containing protein	Regulator
GFB63_RS10925	-	1171370..1171666 (+)	297	Protein_1151	cysteine peptidase family C39 domain-containing protein	-
GFB63_RS10930	comA	1171832..1172227 (+)	396	WP_252989162.1	ABC transporter transmembrane domain-containing protein	Regulator
GFB63_RS10935 (GFB63_06210)	comA	1172311..1172781 (+)	471	WP_265578820.1	ABC transporter transmembrane domain-containing protein	Regulator
GFB63_RS06045 (GFB63_06215)	-	1172836..1173405 (+)	570	WP_265578821.1	ATP-binding cassette domain-containing protein	-
GFB63_RS06050 (GFB63_06220)	-	1173512..1173778 (+)	267	WP_228024372.1	DUF805 domain-containing protein	-
GFB63_RS10605	-	1173989..1174468 (-)	480	WP_228024373.1	DUF4153 domain-containing protein	-
GFB63_RS10610	-	1174910..1175281 (-)	372	WP_224107488.1	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35312.78 Da
• Isoelectric Point: 5.1031

>NTDB_id=395480 GFB63_RS06030 WP_111679231.1 1170233..1171132(+) (comR) [Streptococcus thermophilus strain TK-P3A]
MNIKDSIGLRIKTEREHQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALVVIEKS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=395480 GFB63_RS06030 WP_111679231.1 1170233..1171132(+) (comR) [Streptococcus thermophilus strain TK-P3A]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACACCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GTTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGCAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGTTGTCATAGAAAAATCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (75-292)

• Helix-turn-helix (HTH_3) (11-66)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	99.331	100	0.993
comR	Streptococcus thermophilus LMD-9	98.662	100	0.987
comR	Streptococcus salivarius strain HSISS4	94.649	100	0.946
comR	Streptococcus salivarius SK126	94.314	100	0.943
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	41.806	100	0.418