Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   GFB63_RS04710 Genome accession   NZ_CP045596
Coordinates   911042..912313 (+) Length   423 a.a.
NCBI ID   WP_193838419.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain TK-P3A     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 906042..917313
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GFB63_RS04680 (GFB63_04810) - 906375..906812 (-) 438 WP_002886318.1 LytTR family DNA-binding domain-containing protein -
  GFB63_RS04685 (GFB63_04815) - 906991..907296 (+) 306 WP_084830425.1 hypothetical protein -
  GFB63_RS04690 (GFB63_04820) mutL 907348..909291 (+) 1944 WP_011680601.1 DNA mismatch repair endonuclease MutL -
  GFB63_RS04695 (GFB63_04825) - 909422..909643 (+) 222 WP_011680602.1 hypothetical protein -
  GFB63_RS04700 (GFB63_04830) ruvA 909795..910385 (+) 591 WP_111679083.1 Holliday junction branch migration protein RuvA -
  GFB63_RS04705 (GFB63_04835) - 910392..910946 (+) 555 WP_111679085.1 DNA-3-methyladenine glycosylase I -
  GFB63_RS04710 (GFB63_04840) cinA 911042..912313 (+) 1272 WP_193838419.1 competence/damage-inducible protein A Machinery gene
  GFB63_RS04715 (GFB63_04845) recA 912349..913488 (+) 1140 WP_011680606.1 recombinase RecA Machinery gene
  GFB63_RS04720 (GFB63_04850) spx 913665..914063 (+) 399 WP_002949058.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45885.31 Da        Isoelectric Point: 5.2053

>NTDB_id=395469 GFB63_RS04710 WP_193838419.1 911042..912313(+) (cinA) [Streptococcus thermophilus strain TK-P3A]
MKAELIAVGTEILTGQITNTNAQFLSEKLAELGIDVYFHTAVGDNENRLLSVLDQSSKRSDLVILCGGLGPTEDDLTKQS
LAKFLGKELIFDEEASKKLDSFFATRPKHTRTPNNERQAQIVEGAVPLQNLTGLAVGGIITVEGVTYVVLPGPPSELKPM
VNRELIPALTENHTTLYSRVLRFFGVGESQLVTIIKDLIVNQTDPTIAPYAKVGEVTLRLSTKASSQEEADRKLDVLEEQ
IRSTKTLDGKSLSDLIYGYGESNSLAYEVFYLLKKYGKTITAAESLTAGLFQASVADFPGASQVFKGGFVTYSMEEKAKM
LGIPLSKLEEHGVVSHFTAEKMAEGARVKTGSDYGIALTGVAGPDALEGHQAGTVFIGIADRNQVRSIMVVIGGRSRSDV
RYISTLYAFNLVRQALLQEDNSI

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=395469 GFB63_RS04710 WP_193838419.1 911042..912313(+) (cinA) [Streptococcus thermophilus strain TK-P3A]
ATGAAAGCTGAATTGATTGCAGTAGGAACTGAAATTCTTACAGGGCAAATCACCAATACCAATGCCCAATTTTTATCTGA
AAAACTAGCTGAATTAGGAATTGACGTGTATTTTCACACAGCGGTAGGAGACAATGAAAACCGTCTACTTTCAGTCTTAG
ACCAGTCTAGTAAACGTAGCGATTTAGTTATACTCTGTGGAGGACTTGGCCCTACTGAGGATGACTTAACCAAACAATCA
TTGGCTAAGTTTTTAGGCAAAGAACTCATTTTTGATGAGGAGGCAAGTAAAAAACTGGATAGTTTCTTTGCTACTCGTCC
TAAACATACACGAACGCCTAATAATGAACGCCAAGCGCAAATTGTTGAGGGGGCTGTCCCCTTGCAAAATCTCACAGGTC
TGGCAGTTGGAGGAATTATTACTGTTGAAGGAGTGACCTATGTTGTCTTGCCTGGTCCGCCAAGTGAACTCAAACCTATG
GTGAACCGAGAGCTTATTCCAGCTCTTACAGAGAATCATACTACGCTTTATTCTAGAGTCCTAAGGTTTTTTGGTGTTGG
AGAAAGTCAATTGGTGACTATTATTAAAGATCTCATTGTTAACCAAACAGACCCAACCATTGCGCCCTATGCTAAAGTGG
GAGAAGTGACCCTTCGCTTATCAACAAAGGCATCGTCGCAAGAAGAAGCGGATCGAAAACTAGATGTTTTAGAAGAACAA
ATTCGTTCTACTAAAACTCTAGATGGAAAAAGCTTGTCTGATCTCATCTATGGATATGGAGAATCAAATAGCTTAGCTTA
TGAAGTGTTCTATTTGCTTAAGAAATATGGCAAAACTATTACTGCAGCTGAAAGTTTAACAGCTGGCTTATTTCAAGCTA
GTGTTGCTGATTTTCCTGGAGCTTCACAAGTATTCAAGGGTGGTTTTGTCACCTATAGCATGGAAGAAAAAGCTAAAATG
TTGGGTATTCCCTTATCTAAATTAGAAGAGCATGGTGTTGTTAGTCATTTTACAGCAGAAAAAATGGCTGAGGGTGCCCG
AGTTAAGACAGGTAGTGATTACGGAATTGCGCTTACTGGAGTAGCAGGACCAGATGCTTTGGAAGGGCATCAAGCAGGTA
CAGTCTTTATTGGTATTGCCGATAGAAACCAAGTGAGGTCAATTATGGTTGTTATAGGTGGAAGAAGTCGATCTGATGTT
AGATATATCAGTACACTCTATGCCTTTAACCTAGTTCGCCAAGCTTTATTACAAGAGGACAACTCAATTTAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)

Competence-damaged protein (CinA)

(264-415)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

74.224

99.054

0.735
  cinA Streptococcus mitis NCTC 12261

73.031

99.054

0.723
  cinA Streptococcus pneumoniae TIGR4

71.838

99.054

0.712
  cinA Streptococcus pneumoniae Rx1

71.599

99.054

0.709
  cinA Streptococcus pneumoniae R6

71.599

99.054

0.709
  cinA Streptococcus pneumoniae D39

71.36

99.054

0.707
  cinA Streptococcus mutans UA159

69.834

99.527

0.695
  cinA Streptococcus suis isolate S10

54.327

98.345

0.534
  cinA Bacillus subtilis subsp. subtilis str. 168

44.656

99.527

0.444

Multiple sequence alignment