Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   HICON_RS03810 Genome accession   NC_014922
Coordinates   772786..774123 (+) Length   445 a.a.
NCBI ID   WP_013527438.1    Uniprot ID   A0AAV2U4Z0
Organism   Haemophilus influenzae F3047     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 767786..779123
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HICON_RS03785 (HICON_09750) - 767851..770445 (-) 2595 WP_013527434.1 penicillin-binding protein 1A -
  HICON_RS03790 (HICON_09760) comA 770544..771341 (+) 798 WP_013527435.1 pilus assembly protein PilM Machinery gene
  HICON_RS03795 (HICON_09770) comB 771342..771848 (+) 507 WP_006995134.1 competence protein ComB Machinery gene
  HICON_RS03800 comC 771845..772366 (+) 522 WP_005662592.1 competence protein ComC Machinery gene
  HICON_RS03805 (HICON_09790) comD 772363..772776 (+) 414 WP_013527437.1 pilus assembly protein PilP Machinery gene
  HICON_RS03810 (HICON_09800) comE 772786..774123 (+) 1338 WP_013527438.1 type IV pilus secretin PilQ Machinery gene
  HICON_RS03815 (HICON_09810) - 774136..774822 (+) 687 WP_011272045.1 ComF family protein -
  HICON_RS03820 (HICON_09820) nfuA 774898..775494 (+) 597 WP_005649300.1 Fe-S biogenesis protein NfuA -
  HICON_RS03825 (HICON_09830) nudC 775561..776355 (+) 795 WP_005686893.1 NAD(+) diphosphatase -
  HICON_RS03830 (HICON_09840) - 776391..776981 (+) 591 WP_005686892.1 YjaG family protein -
  HICON_RS03835 (HICON_09850) - 777121..777393 (+) 273 WP_005630954.1 HU family DNA-binding protein -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 49160.41 Da        Isoelectric Point: 8.2628

>NTDB_id=39455 HICON_RS03810 WP_013527438.1 772786..774123(+) (comE) [Haemophilus influenzae F3047]
MKKYFLKCGYFLVCFCLPLIVFANPKTDNERFFIRLSQAPLAQTLEQLAFQQDVNLVMGERLEGNISLKLNNIDMPRLLK
IIAKSKHLTLNKDDGVYYLNGSQSGKGQVAGNLTTNEPHLVSHTVKLHFAKASELMKSLTTGSGSLLSSTGSITFDDRSN
LLVIQDEPRSVQNIKKLIAEMDKPIEQIAIEARIVTITDESLKELGVRWGIFNPTENARRVAGSLTGNSFENIADNLNVN
FATTTTPAGSIALQVAKINGRLLDLELSALERENNVEIIASPRLLTTNKKSASIKQGTEIPYIVSNTRNDTQSVEFREAV
LGLEVTPHISKDNNILLDLLVSQNSPGSRVAYGQNEVVSIDKQEINTQVFAKDGETIVLGGVFHDTITKSEDKVPLLGDI
PVIKRLFSKESERHQKRELVIFVTPHILKAGETLEALKQKSAGKK

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=39455 HICON_RS03810 WP_013527438.1 772786..774123(+) (comE) [Haemophilus influenzae F3047]
ATGAAGAAATATTTTTTAAAGTGCGGTTATTTTTTAGTGTGTTTTTGTTTGCCATTAATCGTTTTTGCTAATCCTAAAAC
AGATAACGAACGTTTTTTTATTCGTTTATCGCAAGCACCTTTAGCTCAAACACTGGAGCAATTAGCTTTTCAACAAGATG
TGAATTTAGTGATGGGTGAGAGGTTAGAAGGCAATATTTCTTTGAAATTAAACAATATTGATATGCCACGTTTGCTAAAA
ATAATCGCAAAAAGTAAGCATCTTACTTTGAATAAAGATGATGGAGTTTATTATTTAAACGGCAGTCAATCTGGCAAAGG
TCAAGTTGCAGGAAATCTTACGACAAATGAACCGCACTTAGTCAGCCACACGGTAAAACTTCATTTTGCTAAAGCCTCTG
AATTAATGAAATCCTTAACAACAGGAAGTGGATCTTTGCTTTCTTCTACGGGGAGCATTACCTTTGATGATCGCAGTAAT
TTGCTGGTTATTCAGGATGAACCTCGTTCTGTGCAAAATATCAAAAAACTGATTGCTGAAATGGATAAGCCTATTGAACA
GATCGCTATTGAAGCGCGAATTGTGACAATTACGGATGAGAGTTTGAAAGAACTTGGCGTTCGGTGGGGGATTTTTAATC
CAACTGAAAATGCAAGACGAGTTGCGGGCAGCCTTACAGGCAATAGCTTTGAAAATATTGCGGATAATCTTAATGTAAAT
TTTGCGACAACGACGACACCTGCTGGCTCTATAGCATTACAAGTCGCGAAAATTAATGGGCGATTGCTTGATTTAGAATT
GAGTGCGTTGGAGCGTGAAAATAATGTAGAAATTATTGCAAGTCCTCGCTTACTCACTACCAATAAGAAAAGTGCGAGCA
TTAAACAGGGGACAGAAATTCCTTACATCGTGAGTAATACTCGTAACGATACGCAATCTGTGGAATTTCGTGAGGCAGTA
CTTGGTTTGGAAGTGACGCCACATATTTCTAAAGATAACAATATCTTACTTGATTTATTGGTAAGTCAAAATTCCCCTGG
TTCTCGTGTCGCTTATGGACAAAATGAGGTGGTTTCTATTGATAAGCAAGAAATTAATACTCAGGTTTTTGCCAAAGATG
GGGAAACCATTGTGCTTGGCGGCGTATTTCACGACACAATCACGAAAAGCGAAGATAAAGTGCCATTGCTTGGCGATATA
CCCGTTATTAAACGATTATTTAGCAAAGAAAGTGAACGACATCAAAAACGTGAGCTCGTGATTTTCGTCACGCCGCATAT
TTTAAAAGCAGGAGAAACGTTAGAGGCGTTGAAACAAAAAAGTGCGGGGAAAAAATAA

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(269-429)

Bacterial type II/III secretion system short domain (Secretin_N)

(123-187)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae 86-028NP

99.326

100

0.993
  comE Haemophilus influenzae Rd KW20

97.753

100

0.978
  comE Glaesserella parasuis strain SC1401

52.235

95.506

0.499
  pilQ Vibrio campbellii strain DS40M4

42.959

94.157

0.404
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

42.233

92.584

0.391
  pilQ Vibrio cholerae strain A1552

42.233

92.584

0.391

Multiple sequence alignment