Detailed information NTG0393766

Bioinformatically predicted

Overview

• Name: pilC
• Type: Machinery gene
• Locus tag: FIU88_RS09850
• Genome accession: NZ_CP045399
• Coordinates: 2146521..2147753 (+)
• Length: 410 a.a.
• NCBI ID: WP_152479099.1
• Uniprot ID: A0A5P9HF25
• Organism: Halomonas sp. THAF12
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2141521..2152753

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FIU88_RS19515	-	2143851..2144414 (-)	564	WP_301339534.1	pilin	-
FIU88_RS09845 (FIU88_09875)	pilB	2144703..2146496 (+)	1794	WP_152479098.1	type IV-A pilus assembly ATPase PilB	Machinery gene
FIU88_RS09850 (FIU88_09880)	pilC	2146521..2147753 (+)	1233	WP_152479099.1	type II secretion system F family protein	Machinery gene
FIU88_RS09860 (FIU88_09885)	-	2147948..2148592 (-)	645	WP_016856438.1	TetR/AcrR family transcriptional regulator	-
FIU88_RS09865 (FIU88_09890)	lexA	2148836..2149498 (+)	663	WP_016856439.1	transcriptional repressor LexA	-
FIU88_RS09870 (FIU88_09895)	dinB	2149543..2150598 (+)	1056	WP_152479101.1	DNA polymerase IV	-
FIU88_RS09875 (FIU88_09900)	purU	2150789..2151643 (-)	855	WP_152479102.1	formyltetrahydrofolate deformylase	-

Sequence

Protein

• Length: 410 a.a.
• Molecular weight: 45121.88 Da
• Isoelectric Point: 9.8124

>NTDB_id=393766 FIU88_RS09850 WP_152479099.1 2146521..2147753(+) (pilC) [Halomonas sp. THAF12]
MATAIYHKGQKLRLYRWHWSGKGPQGRKISGEIIAKSRVEVEKELSGQNIIVKTIRRKSGIGNGMGKVKPRDIMLFARQM
ATMIRAGVPALQAFQVVAESMRKPAMRGLVQELMNEVAAGASFSETLRRHPAYFDRLFCNLVEAGEQSGSLDRMLERVAT
YKEKVESLKARVKKALWYPTAVIAVGIGVTAILLIKVVPQFESLFQGFGAELPAMTRMTIQLSELAQQYWLWALGAVVAA
IFFIRAGIKRSEPFAYRMHALALRLPVIGDILDKSCVARYSRTLATTFGAGVPLVEALETAAGASGNKVYERAVEQVRDD
VATGQQLHFAMRLTEQFPALAVQMVGIGEEAGALDAMLNRVADYYEEDVDNKVDALTSLLEPFIIVVLGVLVGGLVISMY
LPIFELGSVI

Nucleotide

• Length: 1233 bp

>NTDB_id=393766 FIU88_RS09850 WP_152479099.1 2146521..2147753(+) (pilC) [Halomonas sp. THAF12]
ATGGCAACGGCCATTTACCACAAGGGCCAGAAGCTCAGGCTGTATCGCTGGCACTGGTCCGGCAAGGGCCCGCAGGGCCG
CAAGATCAGCGGCGAGATCATCGCCAAGAGCCGCGTCGAGGTCGAGAAGGAACTCTCCGGCCAGAACATCATCGTCAAGA
CCATCCGCCGCAAGAGCGGCATCGGCAACGGCATGGGCAAGGTCAAGCCGCGCGACATCATGCTGTTCGCCCGCCAGATG
GCGACCATGATCCGCGCCGGCGTGCCGGCCCTGCAGGCCTTCCAGGTGGTGGCCGAGAGCATGAGGAAGCCGGCCATGCG
CGGCCTGGTGCAGGAGCTGATGAACGAGGTCGCCGCCGGCGCCAGCTTCTCCGAGACGCTACGGCGTCATCCGGCCTACT
TCGACCGGCTGTTCTGCAACCTGGTGGAGGCCGGCGAGCAGTCCGGCTCACTGGACCGCATGCTCGAGCGCGTGGCCACC
TACAAGGAGAAGGTGGAATCGCTCAAGGCCCGGGTGAAGAAGGCGCTGTGGTACCCCACCGCGGTGATCGCGGTGGGCAT
CGGCGTCACCGCGATCCTGCTGATCAAGGTGGTGCCGCAGTTCGAGAGCCTGTTCCAGGGCTTCGGCGCCGAGCTGCCGG
CGATGACGCGCATGACCATCCAGCTCTCGGAGCTGGCCCAGCAGTACTGGCTGTGGGCGCTGGGCGCGGTGGTGGCCGCC
ATCTTCTTCATTCGCGCCGGCATCAAGCGCTCCGAGCCCTTCGCCTACCGCATGCACGCCCTGGCGCTGCGCCTTCCGGT
GATCGGCGACATCCTCGACAAGTCCTGCGTGGCCCGCTACTCACGCACCCTGGCCACCACCTTCGGCGCCGGCGTGCCGC
TGGTCGAGGCACTGGAGACCGCCGCCGGCGCCTCCGGCAACAAGGTCTACGAGCGCGCGGTCGAACAGGTCCGCGACGAC
GTCGCCACCGGCCAGCAGCTGCACTTCGCCATGCGCCTGACCGAGCAGTTCCCGGCGCTGGCGGTGCAGATGGTCGGCAT
CGGCGAGGAAGCCGGCGCCCTGGACGCCATGCTCAACCGGGTGGCGGACTACTACGAGGAAGACGTCGACAACAAGGTCG
ACGCCCTCACCTCGCTGCTCGAGCCGTTCATCATCGTGGTGCTGGGCGTGCTGGTCGGCGGGCTGGTGATCTCGATGTAC
CTGCCGATCTTCGAGCTGGGCAGCGTGATCTAA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (281-402)

• Type II secretion system (T2SS), protein F (T2SSF) (76-199)

3D structure

• AlphaFold DB: A0A5P9HF25

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilC	Pseudomonas stutzeri DSM 10701	55.19	96.341	0.532
pilC	Acinetobacter baylyi ADP1	53.401	96.829	0.517
pilC	Acinetobacter baumannii D1279779	53.149	96.829	0.515
pilC	Legionella pneumophila strain ERS1305867	50.498	98.049	0.495
pilC	Vibrio cholerae strain A1552	45.906	98.293	0.451
pilC	Vibrio campbellii strain DS40M4	43.25	97.561	0.422
pilG	Neisseria gonorrhoeae MS11	41.119	100	0.412
pilG	Neisseria meningitidis 44/76-A	41.119	100	0.412