Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   FSA28_RS09940 Genome accession   NZ_CP044495
Coordinates   1968322..1969578 (-) Length   418 a.a.
NCBI ID   WP_002266115.1    Uniprot ID   -
Organism   Streptococcus mutans strain UA140     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1963322..1974578
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FSA28_RS09895 (FSA28_1736) - 1963515..1963814 (-) 300 WP_002262384.1 DUF1292 domain-containing protein -
  FSA28_RS09900 (FSA28_1737) ruvX 1963895..1964314 (-) 420 WP_002262385.1 Holliday junction resolvase RuvX -
  FSA28_RS09905 (FSA28_1738) - 1964311..1964580 (-) 270 WP_002262386.1 IreB family regulatory phosphoprotein -
  FSA28_RS09910 (FSA28_1739) brsR 1964748..1965182 (+) 435 WP_002266979.1 bacteriocin genes transcriptional regulator BrsR Regulator
  FSA28_RS09915 (FSA28_1740) brsM 1965195..1965641 (+) 447 WP_002262388.1 bacteriocin genes regulator BrsM Regulator
  FSA28_RS09920 - 1965632..1965843 (-) 212 Protein_1844 hypothetical protein -
  FSA28_RS09925 (FSA28_1741) - 1965972..1966397 (-) 426 WP_002270749.1 hypothetical protein -
  FSA28_RS09930 (FSA28_1742) spx 1966648..1967046 (-) 399 WP_002262391.1 transcriptional regulator Spx -
  FSA28_RS09935 (FSA28_1743) recA 1967131..1968282 (-) 1152 WP_002262392.1 recombinase RecA Machinery gene
  FSA28_RS09940 (FSA28_1744) cinA 1968322..1969578 (-) 1257 WP_002266115.1 competence/damage-inducible protein A Machinery gene
  FSA28_RS09945 (FSA28_1745) - 1969727..1970287 (-) 561 WP_002271569.1 DNA-3-methyladenine glycosylase I -
  FSA28_RS09950 (FSA28_1746) ruvA 1970369..1970962 (-) 594 WP_002266975.1 Holliday junction branch migration protein RuvA -
  FSA28_RS09955 (FSA28_1747) mutL 1971144..1973099 (-) 1956 WP_002264544.1 DNA mismatch repair endonuclease MutL -
  FSA28_RS09960 - 1973324..1973602 (+) 279 Protein_1852 transposase -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45718.51 Da        Isoelectric Point: 6.2714

>NTDB_id=390471 FSA28_RS09940 WP_002266115.1 1968322..1969578(-) (cinA) [Streptococcus mutans strain UA140]
MKSEIIAVGTEILTGQIVNTNSQFLSEKFAELGIDVYFQTAVGDNEERLLSVLKIAKERSDLIVLCGGLGPTEDDLTKQT
LAKFLKRELVFDKTAQERLDEFFASRPTSMRTPNNECQAQIIAGSQPLSNKTGLAVGGLLEADGVTYVVLPGPPSELKPM
VNKELLPYLSKTSEKLYSRVLRFFGIGESHLVTLLHDLIAEQTDPTIAPYAKTGEVTIRLSTKAHRQKEADSKLDKLEKK
IITIDNLADYFYGYGEENSLPQVVFDLLKEKGKTITAAESLTAGLFQARLADFAGASDIFKGGFITYSIEEKARMLGIPF
EDLQLHGVVSAFTAEKMAERSRQLTQADLAVSLTGVAGPDSLEGQPAGTVFIGLSSSKRTMAIKVLIGGRSRSDVRYIAV
LHAFNLVRQTLLSHKNLV

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=390471 FSA28_RS09940 WP_002266115.1 1968322..1969578(-) (cinA) [Streptococcus mutans strain UA140]
ATGAAATCTGAGATCATTGCTGTTGGAACAGAAATTTTAACAGGACAAATTGTTAATACTAATAGTCAATTTTTATCAGA
AAAATTCGCAGAATTAGGAATTGATGTTTATTTTCAAACAGCAGTTGGTGATAATGAAGAACGCCTTTTATCTGTTTTGA
AAATTGCAAAGGAACGTAGTGATTTAATCGTACTTTGCGGTGGTTTGGGACCAACAGAAGATGATTTAACAAAACAAACC
TTAGCAAAATTTTTGAAAAGAGAATTGGTATTTGATAAAACAGCTCAAGAACGTCTAGATGAATTTTTTGCATCACGTCC
AACATCTATGCGCACGCCAAATAATGAATGTCAGGCGCAGATTATAGCAGGAAGTCAGCCTTTATCTAATAAAACAGGCT
TAGCAGTTGGGGGGCTTTTGGAAGCAGATGGAGTGACTTATGTTGTATTACCTGGTCCGCCTAGCGAATTGAAGCCTATG
GTTAACAAAGAGTTACTCCCTTATTTATCAAAAACTTCTGAGAAGCTTTATTCTCGTGTGTTACGCTTTTTTGGTATTGG
TGAGAGTCATCTAGTGACCTTGTTGCATGACTTAATAGCGGAGCAAACAGATCCCACAATTGCTCCTTATGCTAAGACAG
GCGAGGTAACAATACGTTTATCAACAAAAGCCCATAGGCAGAAAGAAGCAGATAGTAAGTTAGATAAGTTGGAAAAGAAA
ATTATAACTATTGATAACTTGGCTGATTATTTTTATGGTTATGGTGAAGAAAATTCATTACCACAGGTTGTATTTGATCT
GCTTAAGGAAAAGGGTAAAACGATTACAGCAGCTGAAAGTTTAACAGCAGGCCTTTTTCAGGCAAGATTAGCAGATTTTG
CAGGAGCATCTGATATCTTTAAGGGAGGTTTTATAACTTACAGTATAGAAGAGAAGGCTAGAATGCTAGGTATTCCCTTT
GAAGATCTCCAACTTCATGGGGTTGTTAGTGCTTTTACTGCTGAAAAGATGGCAGAGCGCTCCCGCCAGCTGACTCAAGC
AGATTTGGCTGTTTCTTTAACAGGAGTTGCAGGTCCGGATAGCTTAGAAGGTCAGCCGGCAGGGACAGTTTTTATCGGTT
TGTCAAGTTCCAAAAGAACAATGGCAATCAAAGTGTTAATTGGCGGACGCAGTCGGTCTGATGTGCGTTATATCGCTGTT
TTACATGCTTTTAATTTAGTACGTCAAACTTTATTATCTCATAAAAATTTAGTATAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Competence-damaged protein (CinA)

(259-411)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

99.761

100

0.998
  cinA Streptococcus mitis SK321

72.249

100

0.722
  cinA Streptococcus mitis NCTC 12261

71.77

100

0.718
  cinA Streptococcus pneumoniae TIGR4

70.574

100

0.706
  cinA Streptococcus pneumoniae Rx1

70.335

100

0.703
  cinA Streptococcus pneumoniae R6

70.335

100

0.703
  cinA Streptococcus pneumoniae D39

70.096

100

0.701
  cinA Streptococcus suis isolate S10

55.474

98.325

0.545
  cinA Bacillus subtilis subsp. subtilis str. 168

45.763

98.804

0.452

Multiple sequence alignment