Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   FSA31_RS09515 Genome accession   NZ_CP044492
Coordinates   1892379..1893635 (-) Length   418 a.a.
NCBI ID   WP_002284634.1    Uniprot ID   -
Organism   Streptococcus mutans strain T8     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1887379..1898635
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FSA31_RS09470 (FSA31_1867) - 1887571..1887870 (-) 300 WP_002262384.1 DUF1292 domain-containing protein -
  FSA31_RS09475 (FSA31_1868) ruvX 1887951..1888370 (-) 420 WP_002284631.1 Holliday junction resolvase RuvX -
  FSA31_RS09480 (FSA31_1869) - 1888367..1888636 (-) 270 WP_002262386.1 IreB family regulatory phosphoprotein -
  FSA31_RS09485 (FSA31_1870) brsR 1888804..1889238 (+) 435 WP_002284632.1 bacteriocin genes transcriptional regulator BrsR Regulator
  FSA31_RS09490 (FSA31_1871) brsM 1889251..1889697 (+) 447 WP_002284633.1 bacteriocin genes regulator BrsM Regulator
  FSA31_RS09495 - 1889688..1889899 (-) 212 Protein_1772 hypothetical protein -
  FSA31_RS09500 (FSA31_1872) - 1890028..1890453 (-) 426 WP_002266116.1 hypothetical protein -
  FSA31_RS09505 (FSA31_1873) spx 1890705..1891103 (-) 399 WP_002262391.1 transcriptional regulator Spx -
  FSA31_RS09510 (FSA31_1874) recA 1891188..1892339 (-) 1152 WP_002262392.1 recombinase RecA Machinery gene
  FSA31_RS09515 (FSA31_1875) cinA 1892379..1893635 (-) 1257 WP_002284634.1 competence/damage-inducible protein A Machinery gene
  FSA31_RS09520 (FSA31_1876) - 1893784..1894344 (-) 561 WP_002284635.1 DNA-3-methyladenine glycosylase I -
  FSA31_RS09525 (FSA31_1877) ruvA 1894426..1895019 (-) 594 WP_002262395.1 Holliday junction branch migration protein RuvA -
  FSA31_RS09530 (FSA31_1878) mutL 1895202..1897157 (-) 1956 WP_002268465.1 DNA mismatch repair endonuclease MutL -
  FSA31_RS09535 - 1897382..1897660 (+) 279 Protein_1780 transposase -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45791.56 Da        Isoelectric Point: 6.2714

>NTDB_id=390339 FSA31_RS09515 WP_002284634.1 1892379..1893635(-) (cinA) [Streptococcus mutans strain T8]
MKSEIIAVGTEILTGQIVNTNSQFLSEKFAELGIDVYFQTAVGDNEERLLSVLKIAKERSDLIVLCGGLGPTEDDLTKQT
LAKFLKRELVFDKTAQERLDEFFASRPTSMRTPNNECQAQIIAGSQPLSNKTGLAVGGLLEADGVTYVVLPGPPSELKPM
VNKELLPYLSKTSEKLYSRVLRFFGIGESHLVTWLHDLIAEQTDPTIAPYAKTGEVTIRLSTKAHRQKEADSKLDKLEKK
IITIDNLADYFYGYGEENSLPQVVFDLLKEKGKTITAAESLTAGLFQARLADFAGASDIFKGGFITYSIEEKARMLGIPF
EDLQLHGVVSAFTAEKMAERSRQLTQADLAVSLTGVAGPDSLEGQPAGTVFIGLSSSKRTMAIKVLIGGRSRSDVRYIAV
LHAFNLVRQTLLSHKNLV

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=390339 FSA31_RS09515 WP_002284634.1 1892379..1893635(-) (cinA) [Streptococcus mutans strain T8]
ATGAAATCTGAGATCATTGCTGTTGGAACAGAAATTTTAACAGGACAAATTGTTAATACTAATAGTCAATTTTTATCAGA
AAAATTCGCAGAATTAGGAATTGATGTTTATTTTCAAACAGCAGTTGGTGATAATGAAGAACGCCTTTTATCTGTTTTGA
AAATTGCAAAGGAACGTAGTGATTTAATCGTACTTTGTGGTGGTTTGGGACCAACAGAAGATGATTTAACAAAACAAACC
CTAGCAAAATTTTTGAAAAGAGAATTGGTATTTGATAAAACAGCTCAAGAACGTCTAGATGAATTTTTTGCATCACGTCC
AACATCTATGCGCACACCAAATAATGAATGTCAGGCGCAGATTATAGCAGGAAGTCAGCCTTTATCTAATAAAACAGGTT
TAGCAGTTGGGGGGCTTTTGGAGGCAGATGGAGTGACTTATGTTGTATTACCTGGTCCGCCTAGCGAATTGAAGCCTATG
GTTAACAAAGAGTTACTCCCTTATTTATCAAAAACTTCTGAGAAGCTTTATTCTCGTGTGTTACGCTTTTTTGGTATTGG
TGAGAGTCATCTAGTGACCTGGTTGCATGACTTAATAGCGGAGCAAACAGATCCCACAATTGCTCCTTATGCTAAGACAG
GCGAGGTAACAATACGTTTATCAACAAAAGCCCATAGGCAGAAAGAAGCAGATAGTAAGTTAGATAAGTTGGAAAAGAAA
ATTATAACTATTGATAACTTGGCTGATTATTTTTATGGTTATGGTGAAGAAAATTCATTACCACAGGTTGTATTTGATCT
GCTTAAGGAAAAGGGTAAAACGATTACAGCAGCTGAAAGTTTAACAGCAGGCCTTTTTCAGGCAAGATTAGCAGATTTTG
CAGGAGCATCTGATATCTTTAAGGGAGGTTTTATAACTTACAGTATAGAAGAGAAGGCTAGAATGCTAGGTATTCCCTTT
GAAGATCTCCAACTTCATGGGGTTGTTAGTGCTTTTACTGCTGAAAAGATGGCAGAGCGCTCCCGCCAGCTGACTCAAGC
AGATTTGGCTGTTTCTTTAACAGGAGTTGCAGGTCCGGATAGCTTAGAAGGTCAGCCGGCAGGGACAGTTTTTATCGGTT
TGTCAAGTTCCAAAAGAACAATGGCAATCAAAGTGTTAATTGGCGGACGCAGTCGGTCTGATGTGCGTTATATCGCTGTT
TTACATGCTTTTAATTTAGTACGTCAAACTTTATTATCTCATAAAAATTTAGTATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Competence-damaged protein (CinA)

(259-411)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

99.522

100

0.995
  cinA Streptococcus mitis SK321

72.249

100

0.722
  cinA Streptococcus mitis NCTC 12261

71.77

100

0.718
  cinA Streptococcus pneumoniae TIGR4

70.574

100

0.706
  cinA Streptococcus pneumoniae Rx1

70.335

100

0.703
  cinA Streptococcus pneumoniae R6

70.335

100

0.703
  cinA Streptococcus pneumoniae D39

70.096

100

0.701
  cinA Streptococcus suis isolate S10

55.474

98.325

0.545
  cinA Bacillus subtilis subsp. subtilis str. 168

45.763

98.804

0.452

Multiple sequence alignment