Detailed information NTG0385752

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: HHM36_RS19205
• Genome accession: NZ_CP051615
• Coordinates: 4042201..4042824 (+)
• Length: 207 a.a.
• NCBI ID: WP_000122253.1
• Uniprot ID: A0A370V1H3
• Organism: Escherichia coli O25b:H4-ST131 strain 2017_APHA
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 4037201..4047824

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HHM36_RS19185 (HHM36_19185)	ampG	4037594..4039069 (-)	1476	WP_000098434.1	muropeptide MFS transporter AmpG	-
HHM36_RS19190 (HHM36_19190)	yajG	4039113..4039691 (-)	579	WP_001295326.1	lipoprotein	-
HHM36_RS19195 (HHM36_19195)	bolA	4039996..4040313 (+)	318	WP_000973448.1	transcriptional regulator BolA	-
HHM36_RS19200 (HHM36_19200)	tig	4040657..4041955 (+)	1299	WP_001198388.1	trigger factor	-
HHM36_RS19205 (HHM36_19205)	clpP	4042201..4042824 (+)	624	WP_000122253.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
HHM36_RS19210 (HHM36_19210)	clpX	4042950..4044224 (+)	1275	WP_000130299.1	ATP-dependent protease ATP-binding subunit ClpX	Regulator
HHM36_RS19215 (HHM36_19215)	lon	4044412..4046766 (+)	2355	WP_001295325.1	endopeptidase La	-
HHM36_RS19220 (HHM36_19220)	hupB	4046975..4047247 (+)	273	WP_001043542.1	nucleoid-associated protein HU-beta	-

Sequence

Protein

• Length: 207 a.a.
• Molecular weight: 23186.65 Da
• Isoelectric Point: 5.6032

>NTDB_id=385752 HHM36_RS19205 WP_000122253.1 4042201..4042824(+) (clpP) [Escherichia coli O25b:H4-ST131 strain 2017_APHA]
MSYSGERDNFAPHMALVPMVIEQTSRGERSFDIYSRLLKERVIFLTGQVEDHMANLIVAQMLFLEAENPEKDIYLYINSP
GGVITAGMSIYDTMQFIKPDVSTICMGQAASMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGYQGQATDIEIHAREILKVK
GRMNELMALHTGQSLEQIERDTERDRFLSAPEAVEYGLVDSILTHRN

Nucleotide

• Length: 624 bp

>NTDB_id=385752 HHM36_RS19205 WP_000122253.1 4042201..4042824(+) (clpP) [Escherichia coli O25b:H4-ST131 strain 2017_APHA]
ATGTCATACAGCGGCGAACGAGATAACTTTGCACCCCATATGGCGCTGGTGCCGATGGTCATTGAACAGACCTCACGAGG
TGAGCGCTCTTTTGATATCTATTCTCGTCTACTTAAGGAACGCGTCATTTTTCTGACTGGCCAGGTTGAAGACCACATGG
CTAACCTGATTGTGGCGCAGATGCTGTTCCTGGAAGCAGAAAACCCAGAAAAAGATATCTATCTGTACATTAACTCTCCA
GGCGGGGTGATTACTGCCGGGATGTCTATCTATGACACCATGCAGTTTATCAAGCCTGATGTCAGCACCATCTGTATGGG
CCAGGCGGCCTCGATGGGCGCTTTCTTGCTGACTGCAGGGGCAAAAGGTAAACGTTTCTGCCTGCCGAATTCGCGCGTGA
TGATTCACCAGCCGTTGGGCGGCTACCAGGGCCAGGCGACCGATATCGAAATTCATGCCCGTGAAATTCTGAAAGTTAAA
GGGCGCATGAATGAACTTATGGCGCTTCATACGGGTCAATCATTAGAACAGATTGAACGTGATACCGAGCGCGATCGCTT
CCTTTCTGCCCCTGAAGCGGTGGAATACGGTCTGGTCGATTCGATTCTGACCCATCGTAATTGA

Domains

Predicted by InterProScan.

• Clp protease (CLP_protease) (26-205)

3D structure

• AlphaFold DB: A0A370V1H3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	69.792	92.754	0.647
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.617	90.821	0.623
clpP	Lactococcus lactis subsp. cremoris KW2	56.701	93.72	0.531
clpP	Streptococcus pneumoniae R6	55.155	93.72	0.517
clpP	Streptococcus pneumoniae TIGR4	55.155	93.72	0.517
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	55.155	93.72	0.517
clpP	Streptococcus pneumoniae Rx1	55.155	93.72	0.517
clpP	Streptococcus pneumoniae D39	55.155	93.72	0.517
clpP	Streptococcus thermophilus LMD-9	54.922	93.237	0.512
clpP	Streptococcus thermophilus LMG 18311	54.922	93.237	0.512
clpP	Streptococcus pyogenes JRS4	55.263	91.787	0.507
clpP	Streptococcus pyogenes MGAS315	55.263	91.787	0.507
clpP	Streptococcus mutans UA159	53.886	93.237	0.502