Detailed information NTG0385753

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: HHM36_RS19210
• Genome accession: NZ_CP051615
• Coordinates: 4042950..4044224 (+)
• Length: 424 a.a.
• NCBI ID: WP_000130299.1
• Uniprot ID: -
• Organism: Escherichia coli O25b:H4-ST131 strain 2017_APHA
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 4037950..4049224

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HHM36_RS19190 (HHM36_19190)	yajG	4039113..4039691 (-)	579	WP_001295326.1	lipoprotein	-
HHM36_RS19195 (HHM36_19195)	bolA	4039996..4040313 (+)	318	WP_000973448.1	transcriptional regulator BolA	-
HHM36_RS19200 (HHM36_19200)	tig	4040657..4041955 (+)	1299	WP_001198388.1	trigger factor	-
HHM36_RS19205 (HHM36_19205)	clpP	4042201..4042824 (+)	624	WP_000122253.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
HHM36_RS19210 (HHM36_19210)	clpX	4042950..4044224 (+)	1275	WP_000130299.1	ATP-dependent protease ATP-binding subunit ClpX	Regulator
HHM36_RS19215 (HHM36_19215)	lon	4044412..4046766 (+)	2355	WP_001295325.1	endopeptidase La	-
HHM36_RS19220 (HHM36_19220)	hupB	4046975..4047247 (+)	273	WP_001043542.1	nucleoid-associated protein HU-beta	-

Sequence

Protein

• Length: 424 a.a.
• Molecular weight: 46316.97 Da
• Isoelectric Point: 4.9297

>NTDB_id=385753 HHM36_RS19210 WP_000130299.1 4042950..4044224(+) (clpX) [Escherichia coli O25b:H4-ST131 strain 2017_APHA]
MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRERSALPTPHEIRNHLDDYVIG
QEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVEN
IIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDT
SKILFICGGAFAGLDKVIANRVETGSGIGFGATVKAKSDKASEGELLAQVEPEDLIKFGLIPEFIGRLPVVATLNELSEE
ALIQILKEPKNALTKQYQALFNLEGVDLEFRDEALDAIAKKAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDE
SVIDGQSKPLLIYGKPEAQQASGE

Nucleotide

• Length: 1275 bp

>NTDB_id=385753 HHM36_RS19210 WP_000130299.1 4042950..4044224(+) (clpX) [Escherichia coli O25b:H4-ST131 strain 2017_APHA]
ATGACAGATAAACGCAAAGATGGCTCAGGCAAATTGCTGTATTGCTCTTTTTGCGGCAAAAGCCAGCATGAAGTGCGCAA
GCTGATTGCCGGTCCATCCGTGTATATCTGCGACGAATGTGTTGATTTATGTAACGACATCATTCGCGAAGAGATTAAAG
AAGTTGCACCGCATCGTGAACGCAGTGCGCTACCGACGCCGCATGAAATTCGCAACCACCTGGACGATTACGTTATCGGT
CAGGAACAGGCGAAAAAAGTGCTGGCGGTCGCGGTATACAACCACTACAAACGTCTGCGCAACGGAGATACCAGCAATGG
CGTCGAGTTGGGCAAAAGTAACATTCTGCTGATCGGTCCGACCGGTTCCGGTAAAACGCTGCTGGCCGAAACGCTGGCGC
GCCTGCTGGACGTTCCGTTCACCATGGCTGACGCAACCACGCTGACCGAAGCCGGTTATGTGGGCGAAGACGTTGAAAAC
ATCATTCAGAAGCTGTTGCAGAAGTGCGATTACGACGTACAGAAAGCGCAGCGCGGGATTGTCTACATCGATGAAATCGA
CAAGATTTCTCGTAAGTCAGACAACCCGTCCATTACCCGAGACGTTTCCGGTGAAGGCGTACAGCAGGCACTGTTAAAAC
TGATCGAAGGTACGGTAGCTGCTGTTCCGCCGCAAGGTGGGCGTAAACATCCGCAGCAGGAATTCTTGCAGGTTGATACC
TCTAAGATCCTGTTCATCTGTGGCGGCGCATTTGCTGGCCTGGATAAAGTGATTGCCAATCGTGTTGAAACCGGCTCCGG
CATTGGTTTTGGCGCGACGGTGAAAGCCAAGTCCGACAAAGCCAGCGAAGGTGAACTGCTGGCGCAGGTTGAACCGGAAG
ATCTGATCAAGTTTGGTCTGATCCCTGAGTTCATTGGTCGTCTGCCGGTTGTCGCAACGTTGAATGAACTGAGCGAAGAA
GCTCTGATTCAGATCCTCAAAGAGCCGAAAAACGCCCTGACCAAGCAGTATCAGGCGCTGTTTAATCTGGAAGGCGTGGA
TCTGGAATTCCGTGACGAGGCGCTGGATGCTATCGCTAAGAAAGCGATGGCGCGTAAAACCGGTGCCCGTGGCCTGCGTT
CCATCGTAGAAGCCGCACTGCTCGATACCATGTACGATCTGCCGTCCATGGAAGATGTCGAAAAAGTGGTTATCGACGAG
TCGGTAATTGATGGTCAAAGCAAACCGTTGCTGATTTATGGTAAGCCGGAAGCGCAACAGGCATCTGGTGAATAA

Domains

Predicted by InterProScan.

• ClpX C4-type zinc finger (zf-C4_ClpX) (13-50)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (317-395)

• AAA domain (Cdc48 subfamily) (AAA_2) (112-310)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	59.85	94.575	0.566
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	55.392	96.226	0.533