Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   HHM37_RS19640 Genome accession   NZ_CP051609
Coordinates   4125846..4126469 (+) Length   207 a.a.
NCBI ID   WP_000122253.1    Uniprot ID   A0A370V1H3
Organism   Escherichia coli O25b:H4-ST131 strain 2019_APHA     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 4120846..4131469
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HHM37_RS19620 (HHM37_19615) ampG 4121239..4122714 (-) 1476 WP_000098434.1 muropeptide MFS transporter AmpG -
  HHM37_RS19625 (HHM37_19620) yajG 4122758..4123336 (-) 579 WP_001295326.1 lipoprotein -
  HHM37_RS19630 (HHM37_19625) bolA 4123641..4123958 (+) 318 WP_000973448.1 transcriptional regulator BolA -
  HHM37_RS19635 (HHM37_19630) tig 4124302..4125600 (+) 1299 WP_001198388.1 trigger factor -
  HHM37_RS19640 (HHM37_19635) clpP 4125846..4126469 (+) 624 WP_000122253.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator
  HHM37_RS19645 (HHM37_19640) clpX 4126595..4127869 (+) 1275 WP_000130299.1 ATP-dependent protease ATP-binding subunit ClpX Regulator
  HHM37_RS19650 (HHM37_19645) lon 4128057..4130411 (+) 2355 WP_001295325.1 endopeptidase La -
  HHM37_RS19655 (HHM37_19650) hupB 4130620..4130892 (+) 273 WP_001043542.1 nucleoid-associated protein HU-beta -

Sequence

Protein


Download         Length: 207 a.a.        Molecular weight: 23186.65 Da        Isoelectric Point: 5.6032

>NTDB_id=385667 HHM37_RS19640 WP_000122253.1 4125846..4126469(+) (clpP) [Escherichia coli O25b:H4-ST131 strain 2019_APHA]
MSYSGERDNFAPHMALVPMVIEQTSRGERSFDIYSRLLKERVIFLTGQVEDHMANLIVAQMLFLEAENPEKDIYLYINSP
GGVITAGMSIYDTMQFIKPDVSTICMGQAASMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGYQGQATDIEIHAREILKVK
GRMNELMALHTGQSLEQIERDTERDRFLSAPEAVEYGLVDSILTHRN

Nucleotide


Download         Length: 624 bp        

>NTDB_id=385667 HHM37_RS19640 WP_000122253.1 4125846..4126469(+) (clpP) [Escherichia coli O25b:H4-ST131 strain 2019_APHA]
ATGTCATACAGCGGCGAACGAGATAACTTTGCACCCCATATGGCGCTGGTGCCGATGGTCATTGAACAGACCTCACGAGG
TGAGCGCTCTTTTGATATCTATTCTCGTCTACTTAAGGAACGCGTCATTTTTCTGACTGGCCAGGTTGAAGACCACATGG
CTAACCTGATTGTGGCGCAGATGCTGTTCCTGGAAGCAGAAAACCCAGAAAAAGATATCTATCTGTACATTAACTCTCCA
GGCGGGGTGATTACTGCCGGGATGTCTATCTATGACACCATGCAGTTTATCAAGCCTGATGTCAGCACCATCTGTATGGG
CCAGGCGGCCTCGATGGGCGCTTTCTTGCTGACTGCAGGGGCAAAAGGTAAACGTTTCTGCCTGCCGAATTCGCGCGTGA
TGATTCACCAGCCGTTGGGCGGCTACCAGGGCCAGGCGACCGATATCGAAATTCATGCCCGTGAAATTCTGAAAGTTAAA
GGGCGCATGAATGAACTTATGGCGCTTCATACGGGTCAATCATTAGAACAGATTGAACGTGATACCGAGCGCGATCGCTT
CCTTTCTGCCCCTGAAGCGGTGGAATACGGTCTGGTCGATTCGATTCTGACCCATCGTAATTGA

Domains

Predicted by InterProScan.

Clp protease (CLP_protease)

(26-205)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A370V1H3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

69.792

92.754

0.647
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

68.617

90.821

0.623
  clpP Lactococcus lactis subsp. cremoris KW2

56.701

93.72

0.531
  clpP Streptococcus pneumoniae R6

55.155

93.72

0.517
  clpP Streptococcus pneumoniae TIGR4

55.155

93.72

0.517
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

55.155

93.72

0.517
  clpP Streptococcus pneumoniae Rx1

55.155

93.72

0.517
  clpP Streptococcus pneumoniae D39

55.155

93.72

0.517
  clpP Streptococcus thermophilus LMD-9

54.922

93.237

0.512
  clpP Streptococcus thermophilus LMG 18311

54.922

93.237

0.512
  clpP Streptococcus pyogenes JRS4

55.263

91.787

0.507
  clpP Streptococcus pyogenes MGAS315

55.263

91.787

0.507
  clpP Streptococcus mutans UA159

53.886

93.237

0.502