Detailed information NTG0385668

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: HHM37_RS19645
• Genome accession: NZ_CP051609
• Coordinates: 4126595..4127869 (+)
• Length: 424 a.a.
• NCBI ID: WP_000130299.1
• Uniprot ID: -
• Organism: Escherichia coli O25b:H4-ST131 strain 2019_APHA
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 4121595..4132869

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HHM37_RS19625 (HHM37_19620)	yajG	4122758..4123336 (-)	579	WP_001295326.1	lipoprotein	-
HHM37_RS19630 (HHM37_19625)	bolA	4123641..4123958 (+)	318	WP_000973448.1	transcriptional regulator BolA	-
HHM37_RS19635 (HHM37_19630)	tig	4124302..4125600 (+)	1299	WP_001198388.1	trigger factor	-
HHM37_RS19640 (HHM37_19635)	clpP	4125846..4126469 (+)	624	WP_000122253.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
HHM37_RS19645 (HHM37_19640)	clpX	4126595..4127869 (+)	1275	WP_000130299.1	ATP-dependent protease ATP-binding subunit ClpX	Regulator
HHM37_RS19650 (HHM37_19645)	lon	4128057..4130411 (+)	2355	WP_001295325.1	endopeptidase La	-
HHM37_RS19655 (HHM37_19650)	hupB	4130620..4130892 (+)	273	WP_001043542.1	nucleoid-associated protein HU-beta	-

Sequence

Protein

• Length: 424 a.a.
• Molecular weight: 46316.97 Da
• Isoelectric Point: 4.9297

>NTDB_id=385668 HHM37_RS19645 WP_000130299.1 4126595..4127869(+) (clpX) [Escherichia coli O25b:H4-ST131 strain 2019_APHA]
MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRERSALPTPHEIRNHLDDYVIG
QEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVEN
IIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDT
SKILFICGGAFAGLDKVIANRVETGSGIGFGATVKAKSDKASEGELLAQVEPEDLIKFGLIPEFIGRLPVVATLNELSEE
ALIQILKEPKNALTKQYQALFNLEGVDLEFRDEALDAIAKKAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDE
SVIDGQSKPLLIYGKPEAQQASGE

Nucleotide

• Length: 1275 bp

>NTDB_id=385668 HHM37_RS19645 WP_000130299.1 4126595..4127869(+) (clpX) [Escherichia coli O25b:H4-ST131 strain 2019_APHA]
ATGACAGATAAACGCAAAGATGGCTCAGGCAAATTGCTGTATTGCTCTTTTTGCGGCAAAAGCCAGCATGAAGTGCGCAA
GCTGATTGCCGGTCCATCCGTGTATATCTGCGACGAATGTGTTGATTTATGTAACGACATCATTCGCGAAGAGATTAAAG
AAGTTGCACCGCATCGTGAACGCAGTGCGCTACCGACGCCGCATGAAATTCGCAACCACCTGGACGATTACGTTATCGGT
CAGGAACAGGCGAAAAAAGTGCTGGCGGTCGCGGTATACAACCACTACAAACGTCTGCGCAACGGAGATACCAGCAATGG
CGTCGAGTTGGGCAAAAGTAACATTCTGCTGATCGGTCCGACCGGTTCCGGTAAAACGCTGCTGGCCGAAACGCTGGCGC
GCCTGCTGGACGTTCCGTTCACCATGGCTGACGCAACCACGCTGACCGAAGCCGGTTATGTGGGCGAAGACGTTGAAAAC
ATCATTCAGAAGCTGTTGCAGAAGTGCGATTACGACGTACAGAAAGCGCAGCGCGGGATTGTCTACATCGATGAAATCGA
CAAGATTTCTCGTAAGTCAGACAACCCGTCCATTACCCGAGACGTTTCCGGTGAAGGCGTACAGCAGGCACTGTTAAAAC
TGATCGAAGGTACGGTAGCTGCTGTTCCGCCGCAAGGTGGGCGTAAACATCCGCAGCAGGAATTCTTGCAGGTTGATACC
TCTAAGATCCTGTTCATCTGTGGCGGCGCATTTGCTGGCCTGGATAAAGTGATTGCCAATCGTGTTGAAACCGGCTCCGG
CATTGGTTTTGGCGCGACGGTGAAAGCCAAGTCCGACAAAGCCAGCGAAGGTGAACTGCTGGCGCAGGTTGAACCGGAAG
ATCTGATCAAGTTTGGTCTGATCCCTGAGTTCATTGGTCGTCTGCCGGTTGTCGCAACGTTGAATGAACTGAGCGAAGAA
GCTCTGATTCAGATCCTCAAAGAGCCGAAAAACGCCCTGACCAAGCAGTATCAGGCGCTGTTTAATCTGGAAGGCGTGGA
TCTGGAATTCCGTGACGAGGCGCTGGATGCTATCGCTAAGAAAGCGATGGCGCGTAAAACCGGTGCCCGTGGCCTGCGTT
CCATCGTAGAAGCCGCACTGCTCGATACCATGTACGATCTGCCGTCCATGGAAGATGTCGAAAAAGTGGTTATCGACGAG
TCGGTAATTGATGGTCAAAGCAAACCGTTGCTGATTTATGGTAAGCCGGAAGCGCAACAGGCATCTGGTGAATAA

Domains

Predicted by InterProScan.

• ClpX C4-type zinc finger (zf-C4_ClpX) (13-50)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (317-395)

• AAA domain (Cdc48 subfamily) (AAA_2) (112-310)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	59.85	94.575	0.566
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	55.392	96.226	0.533