Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   FY406_RS09170 Genome accession   NZ_CP043405
Coordinates   1839345..1840019 (-) Length   224 a.a.
NCBI ID   WP_003088430.1    Uniprot ID   -
Organism   Streptococcus ratti strain ATCC 31377     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1834345..1845019
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FY406_RS09145 (FY406_09145) - 1834573..1835853 (-) 1281 WP_003088421.1 pyrimidine-nucleoside phosphorylase -
  FY406_RS09150 (FY406_09150) - 1835958..1836554 (-) 597 WP_003088423.1 class I SAM-dependent methyltransferase -
  FY406_RS09155 (FY406_09155) coaA 1836651..1837571 (+) 921 WP_003088425.1 type I pantothenate kinase -
  FY406_RS09160 (FY406_09160) rpsT 1837625..1837876 (+) 252 WP_075347106.1 30S ribosomal protein S20 -
  FY406_RS09165 (FY406_09165) ciaH 1838036..1839355 (-) 1320 WP_003088429.1 cell wall metabolism sensor histidine kinase WalK Regulator
  FY406_RS09170 (FY406_09170) ciaR 1839345..1840019 (-) 675 WP_003088430.1 three-component system response regulator CiaR Regulator
  FY406_RS09175 (FY406_09175) - 1841031..1841208 (+) 178 Protein_1760 ISL3 family transposase -
  FY406_RS09180 (FY406_09180) - 1841309..1843855 (-) 2547 WP_003088438.1 M1 family metallopeptidase -
  FY406_RS09185 (FY406_09185) phoU 1843898..1844551 (-) 654 WP_003088439.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25447.25 Da        Isoelectric Point: 4.4918

>NTDB_id=383599 FY406_RS09170 WP_003088430.1 1839345..1840019(-) (ciaR) [Streptococcus ratti strain ATCC 31377]
MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGEEGLYEAESGVYDLILLDLMLPEKSGFQVLKELREKGITTPVLIMTA
KEGLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKYTDKSLVYGDLTVDTSTNTTKVNGKEVELLGKEFDLLVY
FLQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKDTQFGKNLQTLRSVGYILKNAN

Nucleotide


Download         Length: 675 bp        

>NTDB_id=383599 FY406_RS09170 WP_003088430.1 1839345..1840019(-) (ciaR) [Streptococcus ratti strain ATCC 31377]
ATGATAAAGATATTATTAGTAGAAGATGATTTAAGCCTGTCAAATTCCATCTTTGACTTTCTGGATGATTTTGCTGACGT
TATGCAGGTTTTTGATGGGGAAGAGGGGCTTTATGAGGCTGAAAGCGGCGTTTATGATTTAATTTTATTGGACTTGATGT
TGCCAGAAAAGAGCGGTTTTCAGGTTTTGAAGGAATTGCGTGAGAAGGGTATTACAACACCTGTCTTGATTATGACCGCT
AAAGAAGGCTTAGATGATAAGGGACACGGCTTTGAACTGGGAGCTGATGATTATCTGACAAAACCTTTTTATTTAGAAGA
GCTGAAAATGCGTATTCAAGCTCTTCTTAAGCGCTCAGGGAAATATACCGATAAAAGCCTTGTTTACGGTGACTTAACGG
TGGATACATCGACCAATACAACCAAAGTAAATGGTAAGGAAGTTGAGCTGCTTGGCAAGGAGTTCGATTTGCTGGTTTAT
TTCCTGCAGAATCAGAATGTTATTTTGCCTAAATCACAGATTTTTGACCGAATTTGGGGATTTGACAGTGATACGACAAT
TTCTGTCGTTGAGGTCTATGTGTCTAAAATCAGAAAAAAACTAAAAGATACTCAGTTCGGAAAAAACTTGCAGACATTGC
GCAGTGTAGGATATATTTTGAAGAATGCTAATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

94.196

100

0.942
  ciaR Streptococcus pneumoniae Rx1

86.547

99.554

0.862
  ciaR Streptococcus pneumoniae D39

86.547

99.554

0.862
  ciaR Streptococcus pneumoniae R6

86.547

99.554

0.862
  ciaR Streptococcus pneumoniae TIGR4

86.547

99.554

0.862
  micA Streptococcus pneumoniae Cp1015

36.052

100

0.375
  vicR Streptococcus mutans UA159

35.47

100

0.371
  covR Streptococcus salivarius strain HSISS4

35.841

100

0.362
  covR Lactococcus lactis subsp. lactis strain DGCC12653

36.161

100

0.362

Multiple sequence alignment