Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   FY406_RS09165 Genome accession   NZ_CP043405
Coordinates   1838036..1839355 (-) Length   439 a.a.
NCBI ID   WP_003088429.1    Uniprot ID   -
Organism   Streptococcus ratti strain ATCC 31377     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1833036..1844355
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FY406_RS09135 (FY406_09135) - 1833516..1833902 (-) 387 WP_003088417.1 cytidine deaminase -
  FY406_RS09140 (FY406_09140) deoC 1833892..1834554 (-) 663 WP_003088419.1 deoxyribose-phosphate aldolase -
  FY406_RS09145 (FY406_09145) - 1834573..1835853 (-) 1281 WP_003088421.1 pyrimidine-nucleoside phosphorylase -
  FY406_RS09150 (FY406_09150) - 1835958..1836554 (-) 597 WP_003088423.1 class I SAM-dependent methyltransferase -
  FY406_RS09155 (FY406_09155) coaA 1836651..1837571 (+) 921 WP_003088425.1 type I pantothenate kinase -
  FY406_RS09160 (FY406_09160) rpsT 1837625..1837876 (+) 252 WP_075347106.1 30S ribosomal protein S20 -
  FY406_RS09165 (FY406_09165) ciaH 1838036..1839355 (-) 1320 WP_003088429.1 cell wall metabolism sensor histidine kinase WalK Regulator
  FY406_RS09170 (FY406_09170) ciaR 1839345..1840019 (-) 675 WP_003088430.1 three-component system response regulator CiaR Regulator
  FY406_RS09175 (FY406_09175) - 1841031..1841208 (+) 178 Protein_1760 ISL3 family transposase -
  FY406_RS09180 (FY406_09180) - 1841309..1843855 (-) 2547 WP_003088438.1 M1 family metallopeptidase -

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 50144.80 Da        Isoelectric Point: 10.1201

>NTDB_id=383598 FY406_RS09165 WP_003088429.1 1838036..1839355(-) (ciaH) [Streptococcus ratti strain ATCC 31377]
MLIKLRQKNRHGENASFFSHFFGVFTGIFFVMTVIIIQVMRFGIYSSVDDSLKKATKNIDDYVNMAMVRNTMIDDTIGEN
NSEPSFKIKPNGQMAANTDTILYNKKRQVVNNINAFSPLYRIHPKLNNLGDIAEQKAKNIYGQTEKYRIVTVKVDNDFYP
QVKYATIVINTTQLEEANKRYVTIIISVMIVFWLISVIASVYLAKWSRKPILENYEKQKSFVENASHELRTPLAVLQNRL
ESLFRKPEATILESSESIASSLEEVRNMRMLTTNLLNLARRDDGIEPEITEVNPSFFDGTFKNYAMIAQENGKTLHIANK
VSRQIKTDKTLLKQLMTILFDNAVKYTGQEGEIWIDVKTTDRNLIFSVADNGQGISDTDKKRIFDRFYRVDKARTRQKGG
FGLGLSLAKQITDSLKGSIIVKDKKPQGTIFEVRLPASK

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=383598 FY406_RS09165 WP_003088429.1 1838036..1839355(-) (ciaH) [Streptococcus ratti strain ATCC 31377]
ATGCTAATTAAACTGAGACAAAAAAACAGGCATGGAGAGAATGCCTCCTTTTTCAGCCATTTCTTTGGTGTATTTACGGG
CATATTCTTTGTAATGACGGTGATCATCATACAAGTCATGCGCTTTGGTATTTATTCTTCGGTTGATGACAGTCTTAAAA
AAGCAACTAAAAATATTGATGATTATGTCAATATGGCTATGGTCAGAAATACCATGATTGATGATACCATTGGCGAAAAT
AACTCAGAACCTTCCTTTAAAATCAAACCCAATGGTCAAATGGCTGCCAATACGGATACGATTCTTTATAATAAAAAACG
GCAGGTTGTCAATAATATCAATGCTTTTTCACCCTTATACCGCATTCATCCTAAGCTGAATAATCTAGGTGATATTGCCG
AGCAAAAGGCCAAGAATATCTATGGCCAAACGGAAAAATATAGGATTGTAACGGTTAAAGTGGATAATGATTTTTATCCT
CAGGTAAAATATGCAACGATTGTTATTAACACGACTCAGCTGGAGGAAGCTAACAAACGCTATGTGACGATTATTATCAG
CGTTATGATTGTTTTTTGGCTGATTTCAGTTATCGCCAGTGTCTATTTAGCCAAGTGGAGCCGCAAGCCTATTTTAGAGA
ATTACGAAAAGCAGAAATCTTTTGTGGAAAATGCCAGTCACGAACTGCGCACACCGCTGGCCGTTTTGCAAAATCGCTTG
GAAAGCCTATTTAGAAAGCCTGAGGCTACTATTTTAGAATCCTCAGAATCTATCGCTTCCAGTTTGGAAGAAGTCAGAAA
TATGAGGATGCTGACAACTAATCTCCTTAATCTGGCACGTCGTGATGATGGTATTGAACCCGAAATAACAGAGGTTAACC
CCAGCTTTTTTGATGGGACCTTTAAAAATTATGCCATGATTGCGCAGGAAAACGGTAAAACGCTGCACATTGCAAATAAG
GTCAGCCGTCAGATTAAAACTGACAAAACTCTACTCAAACAATTAATGACCATTCTTTTTGACAATGCTGTCAAATACAC
GGGTCAAGAAGGGGAAATTTGGATAGATGTTAAAACAACCGACCGCAATTTGATTTTCTCGGTAGCTGACAACGGTCAGG
GAATTTCAGATACAGATAAAAAGAGAATTTTCGACCGTTTTTACCGCGTTGATAAGGCCAGGACCCGGCAAAAAGGCGGT
TTTGGTCTCGGTTTGTCTCTGGCTAAACAAATTACCGATAGCTTAAAAGGCAGTATTATCGTTAAAGATAAGAAGCCGCA
AGGAACTATTTTTGAAGTTCGTTTGCCTGCCAGTAAGTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(219-284)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(328-438)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

83.144

100

0.831
  ciaH Streptococcus pneumoniae Rx1

55.378

99.544

0.551
  ciaH Streptococcus pneumoniae D39

55.378

99.544

0.551
  ciaH Streptococcus pneumoniae R6

55.378

99.544

0.551
  ciaH Streptococcus pneumoniae TIGR4

55.378

99.544

0.551

Multiple sequence alignment