Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   FY406_RS00065 Genome accession   NZ_CP043405
Coordinates   16053..16760 (-) Length   235 a.a.
NCBI ID   WP_003088928.1    Uniprot ID   -
Organism   Streptococcus ratti strain ATCC 31377     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 11053..21760
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FY406_RS00040 (FY406_00040) rnc 12433..13128 (-) 696 WP_003088921.1 ribonuclease III -
  FY406_RS00050 (FY406_00050) - 13574..13845 (-) 272 Protein_8 DUF454 family protein -
  FY406_RS00055 (FY406_00055) vicX 13908..14711 (-) 804 WP_003088924.1 MBL fold metallo-hydrolase Regulator
  FY406_RS00060 (FY406_00060) vicK 14708..16060 (-) 1353 WP_003088926.1 cell wall metabolism sensor histidine kinase VicK Regulator
  FY406_RS00065 (FY406_00065) vicR 16053..16760 (-) 708 WP_003088928.1 response regulator YycF Regulator
  FY406_RS00070 (FY406_00070) - 17110..17886 (+) 777 WP_003088930.1 amino acid ABC transporter ATP-binding protein -
  FY406_RS00075 (FY406_00075) - 17907..18722 (+) 816 WP_003088931.1 transporter substrate-binding domain-containing protein -
  FY406_RS00080 (FY406_00080) - 19071..19775 (+) 705 WP_003088936.1 amino acid ABC transporter permease -
  FY406_RS00085 (FY406_00085) - 19790..20440 (+) 651 WP_003088938.1 amino acid ABC transporter permease -
  FY406_RS00090 (FY406_00090) endA 20610..21494 (-) 885 WP_003088940.1 DNA/RNA non-specific endonuclease Machinery gene
  FY406_RS00095 (FY406_00095) - 21541..21729 (-) 189 WP_003088941.1 DNA-directed RNA polymerase subunit beta -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 26941.75 Da        Isoelectric Point: 4.8271

>NTDB_id=383540 FY406_RS00065 WP_003088928.1 16053..16760(-) (vicR) [Streptococcus ratti strain ATCC 31377]
MKKILIVDDEKPISDIIKFNLAKEGYDTITAFDGREALTKYEEENPDLIILDLMLPELDGLEVAKEVRKSSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTENIETAVAEENASGMPELVIGDLQILPDAFVAKKHGQEVEL
THREFELLHHLATHTGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=383540 FY406_RS00065 WP_003088928.1 16053..16760(-) (vicR) [Streptococcus ratti strain ATCC 31377]
ATGAAGAAAATTTTAATCGTTGATGACGAAAAACCAATTTCTGATATTATCAAGTTTAATCTGGCCAAAGAAGGTTATGA
CACGATTACGGCTTTTGACGGACGTGAAGCGCTGACTAAGTATGAAGAAGAGAATCCTGATTTAATTATTCTTGATTTGA
TGCTGCCGGAATTAGACGGTCTTGAAGTGGCTAAAGAAGTTCGAAAAAGCAGCCATGTACCTATTATCATGCTTTCAGCC
AAGGACAGCGAATTTGACAAGGTCATCGGACTTGAAATCGGTGCAGATGATTATGTGACAAAACCCTTCTCAAACCGTGA
GCTGCTGGCTCGGATTAAAGCCCACCTGCGCAGAACGGAAAATATTGAAACAGCTGTAGCCGAAGAAAATGCATCGGGCA
TGCCAGAGCTTGTTATTGGGGATCTGCAGATTCTGCCCGATGCTTTTGTCGCTAAAAAGCATGGTCAGGAAGTAGAGCTG
ACCCATCGGGAGTTTGAACTCCTGCATCATCTGGCGACCCATACCGGTCAGGTAATGACCCGTGAGCATTTACTTGAAAC
TGTCTGGGGATACGACTATTTTGGCGATGTCAGAACCGTTGATGTGACTGTTCGCCGCCTGCGTGAAAAAATTGAAGATA
CGCCGAGCCGTCCTGAGTATATTCTGACGAGACGCGGTGTTGGTTATTATATGAAATCATATGACTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

96.17

100

0.962
  micA Streptococcus pneumoniae Cp1015

77.682

99.149

0.77
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.455

98.298

0.447
  covR Streptococcus salivarius strain HSISS4

45.022

98.298

0.443
  scnR Streptococcus mutans UA159

36.638

98.723

0.362

Multiple sequence alignment