Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   FY406_RS00060 Genome accession   NZ_CP043405
Coordinates   14708..16060 (-) Length   450 a.a.
NCBI ID   WP_003088926.1    Uniprot ID   -
Organism   Streptococcus ratti strain ATCC 31377     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 9708..21060
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FY406_RS00040 (FY406_00040) rnc 12433..13128 (-) 696 WP_003088921.1 ribonuclease III -
  FY406_RS00050 (FY406_00050) - 13574..13845 (-) 272 Protein_8 DUF454 family protein -
  FY406_RS00055 (FY406_00055) vicX 13908..14711 (-) 804 WP_003088924.1 MBL fold metallo-hydrolase Regulator
  FY406_RS00060 (FY406_00060) vicK 14708..16060 (-) 1353 WP_003088926.1 cell wall metabolism sensor histidine kinase VicK Regulator
  FY406_RS00065 (FY406_00065) vicR 16053..16760 (-) 708 WP_003088928.1 response regulator YycF Regulator
  FY406_RS00070 (FY406_00070) - 17110..17886 (+) 777 WP_003088930.1 amino acid ABC transporter ATP-binding protein -
  FY406_RS00075 (FY406_00075) - 17907..18722 (+) 816 WP_003088931.1 transporter substrate-binding domain-containing protein -
  FY406_RS00080 (FY406_00080) - 19071..19775 (+) 705 WP_003088936.1 amino acid ABC transporter permease -
  FY406_RS00085 (FY406_00085) - 19790..20440 (+) 651 WP_003088938.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51548.31 Da        Isoelectric Point: 4.5848

>NTDB_id=383539 FY406_RS00060 WP_003088926.1 14708..16060(-) (vicK) [Streptococcus ratti strain ATCC 31377]
MTNTFESSPLFLRILLAVLLILLFIYFVFLNYREYKNNNHIKLLNAKVRSLIAGDYTEKLKFKANPELSELVRNVNDLSE
VFRLTHENLAQEKNRLTSILAYMTDGVLATDRSGKITMINDMAQKQLNLTREQALEYNILDILDDDSYTYNDLITKTPEI
VLNRRDEYDEFITLRIRFALNRRESGFISGLIAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALTE
SVAPSFIKVSLDETNRMMRMITDLLSLSRIDNQTSRLDVELTNFTAFMDYILDRFDQIQSQQSGGKVYEIVRDYSDSSAW
IEIDTDKMTQVIDNILNNAIKYSPDGGKITVNMKTTDTQVILSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGSGLG
LAIAKEIIKQHNGFIWANSEEGKGSTFTIVLPYESDNGTIDEWEEDEDES

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=383539 FY406_RS00060 WP_003088926.1 14708..16060(-) (vicK) [Streptococcus ratti strain ATCC 31377]
ATGACTAATACATTTGAATCAAGTCCTTTATTTTTACGAATATTATTAGCAGTTTTGCTGATTCTGCTCTTTATCTATTT
TGTCTTTCTCAATTACAGAGAATACAAAAACAACAATCACATTAAGCTGTTAAATGCTAAGGTACGCTCTTTGATTGCCG
GTGACTATACCGAAAAGTTAAAGTTCAAGGCTAATCCCGAACTGTCAGAGCTAGTTAGAAATGTCAACGATCTGTCTGAG
GTTTTTCGGCTGACCCATGAAAATCTGGCTCAGGAAAAAAACCGACTGACCAGTATTTTGGCCTATATGACTGACGGGGT
GCTGGCGACAGACCGCAGCGGAAAAATTACCATGATTAATGATATGGCTCAAAAACAGCTCAATCTGACCCGCGAACAAG
CTCTGGAATATAATATCCTTGATATCTTGGATGATGACAGCTATACATACAATGATCTGATTACTAAAACACCTGAGATT
GTTTTAAACCGCCGTGATGAGTATGATGAATTTATCACTTTGCGGATTCGATTTGCTCTGAATCGACGCGAAAGCGGCTT
TATTTCGGGTTTGATTGCAGTTTTGCATGATGCTACTGAGCAGGAAAAAGAAGAGCGCGAACGCCGTCTCTTTGTGTCCA
ATGTCAGTCATGAGCTGCGAACACCGCTGACCTCCGTAAAATCTTATTTGGAAGCTTTGGATGACGGGGCTCTGACTGAA
TCGGTCGCTCCGAGTTTTATAAAGGTCTCGCTGGATGAAACCAACCGAATGATGCGGATGATTACAGACTTACTCAGCCT
GTCGCGGATTGATAATCAGACCAGCCGCTTAGATGTTGAGCTGACCAATTTCACGGCTTTTATGGATTATATTCTCGATC
GCTTTGACCAAATTCAGAGCCAGCAGTCAGGCGGTAAGGTCTATGAAATTGTCAGAGATTATTCTGACAGCTCTGCCTGG
ATTGAAATTGATACAGACAAGATGACTCAGGTGATTGATAACATTTTAAATAATGCTATTAAGTATTCACCTGATGGCGG
TAAGATTACTGTCAATATGAAGACAACCGATACTCAGGTCATTCTCTCCATATCGGATCAGGGTCTGGGAATTCCTAAGA
AGGATCTTCCGCTTATTTTTGATCGTTTTTACCGGGTTGATAAGGCGAGAAGCAGGGCGCAGGGCGGCAGCGGTTTGGGA
CTTGCTATTGCCAAAGAAATTATCAAACAGCACAATGGCTTTATTTGGGCCAACAGTGAAGAAGGCAAGGGCTCAACTTT
TACGATTGTTCTGCCTTATGAAAGCGACAACGGTACAATTGATGAATGGGAGGAAGATGAAGACGAATCATGA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

PAS fold (PAS)

(97-180)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

90.682

97.778

0.887
  micB Streptococcus pneumoniae Cp1015

68.065

95.333

0.649

Multiple sequence alignment