Detailed information NTG0038292

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: SP670_RS06765
• Genome accession: NC_014498
• Coordinates: 1284422..1285072 (-)
• Length: 216 a.a.
• NCBI ID: WP_000387330.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae 670-6B
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1279422..1290072

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SP670_RS06745 (SP670_1362)	-	1280033..1281208 (-)	1176	WP_000655944.1	hypothetical protein	-
SP670_RS06750 (SP670_1363)	-	1281212..1281799 (-)	588	WP_000939880.1	ATP-binding cassette domain-containing protein	-
SP670_RS14635	-	1281832..1282049 (-)	218	Protein_1305	hypothetical protein	-
SP670_RS06760 (SP670_1364)	comEC/celB	1282198..1284438 (-)	2241	WP_000942383.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
SP670_RS06765 (SP670_1365)	comEA/celA/cilE	1284422..1285072 (-)	651	WP_000387330.1	ComEA family DNA-binding protein	Machinery gene
SP670_RS06770 (SP670_1366)	-	1285140..1285709 (-)	570	WP_000443775.1	GNAT family N-acetyltransferase	-
SP670_RS14255 (SP670_1369)	ald	1285886..1286997 (+)	1112	Protein_1309	alanine dehydrogenase	-
SP670_RS13535	-	1287298..1287623 (-)	326	Protein_1310	TfoX/Sxy family protein	-
SP670_RS06795 (SP670_1371)	-	1287626..1288126 (-)	501	WP_000566989.1	GNAT family N-acetyltransferase	-
SP670_RS06800 (SP670_1373)	-	1288319..1289287 (-)	969	WP_000658181.1	PhoH family protein	-
SP670_RS06805 (SP670_1374)	-	1289373..1289588 (-)	216	WP_001232085.1	YozE family protein	-

Sequence

Protein

• Length: 216 a.a.
• Molecular weight: 23229.65 Da
• Isoelectric Point: 5.5171

>NTDB_id=38292 SP670_RS06765 WP_000387330.1 1284422..1285072(-) (comEA/celA/cilE) [Streptococcus pneumoniae 670-6B]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDLVSEKEVNKEEKEEPLEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGLGTASSISKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD

Nucleotide

• Length: 651 bp

>NTDB_id=38292 SP670_RS06765 WP_000387330.1 1284422..1285072(-) (comEA/celA/cilE) [Streptococcus pneumoniae 670-6B]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGAGGATT
TTTCCTGCTAAAACCAGCTCCACAAACACCTGTCAAAGAGACGAATTTGCAGGCTGAAGTCGCAGCTGTTTCCAAGGATT
TGGTATCCGAAAAGGAAGTGAACAAGGAAGAAAAGGAAGAACCCCTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGCCAACAGACTGGTTTGGGGACAGCTTCTTCAATAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATCGACCATCGTGAGGCAAATGG
CAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGGCAAAACAATAGAAAAGCTTAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (151-214)

• SLBB domain (SLBB) (76-126)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus pneumoniae Rx1	100	100	1
comEA/celA/cilE	Streptococcus pneumoniae D39	100	100	1
comEA/celA/cilE	Streptococcus pneumoniae R6	100	100	1
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	97.222	100	0.972
comEA/celA/cilE	Streptococcus mitis NCTC 12261	96.296	100	0.963
comEA/celA/cilE	Streptococcus mitis SK321	90.278	100	0.903
comEA	Lactococcus lactis subsp. cremoris KW2	43.172	100	0.454
comEA	Bacillus subtilis subsp. subtilis str. 168	41.579	87.963	0.366
comEA	Latilactobacillus sakei subsp. sakei 23K	33.476	100	0.361