Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   HB750_RS06435 Genome accession   NZ_CP050273
Coordinates   1308795..1309475 (-) Length   226 a.a.
NCBI ID   WP_002267104.1    Uniprot ID   -
Organism   Streptococcus mutans strain P1     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1303795..1314475
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HB750_RS06425 (HB750_06425) - 1305759..1306385 (-) 627 WP_002264731.1 DUF805 domain-containing protein -
  HB750_RS06430 (HB750_06430) comEC/celB 1306571..1308805 (-) 2235 WP_002296251.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  HB750_RS06435 (HB750_06435) comEA/celA/cilE 1308795..1309475 (-) 681 WP_002267104.1 helix-hairpin-helix domain-containing protein Machinery gene
  HB750_RS06440 (HB750_06440) - 1309615..1310367 (-) 753 WP_002264733.1 lysophospholipid acyltransferase family protein -
  HB750_RS06445 (HB750_06445) - 1310506..1311441 (+) 936 WP_002269713.1 polysaccharide deacetylase family protein -
  HB750_RS06450 (HB750_06450) - 1311530..1312042 (+) 513 WP_002265382.1 HXXEE domain-containing protein -
  HB750_RS06455 (HB750_06455) - 1312088..1313107 (+) 1020 WP_019316272.1 GIY-YIG nuclease family protein -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 24558.90 Da        Isoelectric Point: 8.2999

>NTDB_id=378012 HB750_RS06435 WP_002267104.1 1308795..1309475(-) (comEA/celA/cilE) [Streptococcus mutans strain P1]
MVDEFLDKLKEKKNVFALVGGLVVLLGLGVYFFFPSSNKQEDSLARLKEQSLQVTTKTGKESQKKTQVTTAKSTITVDIK
GAVKHEGVYTLPIDSRINDVIEKAGGFSEKADRKSVNLAQKLQDEAVIYVAAIGENISVIRDSQEGKTSQADKANTKETS
VKGKVNLNTATLADLQTISGIGEKKAQDILDYREANGGFKSVDDLKNISGIGDKTFEKLKDLVSVD

Nucleotide


Download         Length: 681 bp        

>NTDB_id=378012 HB750_RS06435 WP_002267104.1 1308795..1309475(-) (comEA/celA/cilE) [Streptococcus mutans strain P1]
ATGGTTGACGAATTTTTAGATAAACTCAAGGAAAAGAAAAATGTTTTTGCCCTAGTTGGTGGTCTTGTAGTCTTACTGGG
TCTGGGTGTTTATTTCTTTTTTCCTTCTTCCAATAAGCAGGAAGACAGTCTGGCTCGTTTAAAGGAACAATCCCTTCAGG
TAACCACAAAGACTGGCAAAGAAAGTCAAAAGAAGACGCAGGTGACGACTGCCAAATCAACAATAACTGTTGATATTAAA
GGAGCTGTTAAGCATGAGGGCGTCTATACTTTACCGATTGACAGTCGTATTAATGATGTAATAGAAAAAGCGGGAGGTTT
TTCTGAAAAGGCTGATCGCAAATCTGTTAATCTGGCTCAAAAATTACAAGACGAAGCAGTTATTTATGTGGCAGCTATTG
GTGAGAATATTAGTGTCATTAGGGATTCTCAAGAAGGTAAAACCAGTCAGGCAGATAAGGCAAATACTAAAGAAACTTCG
GTAAAAGGTAAGGTTAATCTTAATACTGCCACTTTGGCTGATTTACAGACTATTTCTGGAATCGGTGAGAAGAAAGCTCA
GGATATTCTTGATTACCGTGAAGCCAATGGAGGTTTTAAGTCAGTGGATGATTTGAAAAATATTTCAGGGATTGGCGATA
AAACATTTGAGAAGTTAAAGGATTTAGTCAGTGTTGATTAG

Domains

Predicted by InterProScan.

SLBB domain (SLBB)

(77-130)

Helix-hairpin-helix motif (HHH_3)

(163-223)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus mitis NCTC 12261

42.489

100

0.438
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

42.06

100

0.434
  comEA/celA/cilE Streptococcus mitis SK321

42.241

100

0.434
  comEA/celA/cilE Streptococcus pneumoniae D39

41.631

100

0.429
  comEA/celA/cilE Streptococcus pneumoniae Rx1

41.631

100

0.429
  comEA/celA/cilE Streptococcus pneumoniae R6

41.631

100

0.429
  comEA Lactococcus lactis subsp. cremoris KW2

42.478

100

0.425
  comEA Streptococcus thermophilus LMD-9

57.143

68.142

0.389
  comEA Latilactobacillus sakei subsp. sakei 23K

35.537

100

0.381