Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   HA248_RS07985 Genome accession   NZ_CP050175
Coordinates   1550773..1551450 (-) Length   225 a.a.
NCBI ID   WP_000548991.1    Uniprot ID   A0A501PEF7
Organism   Streptococcus pneumoniae strain PZ900701590     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1545773..1556450
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HA248_RS07960 (HA248_07940) - 1545945..1546574 (-) 630 WP_000762082.1 NAD(P)-dependent oxidoreductase -
  HA248_RS11550 - 1546813..1547176 (+) 364 Protein_1567 hypothetical protein -
  HA248_RS11885 (HA248_07950) - 1547433..1547756 (+) 324 Protein_1568 MazG-like protein -
  HA248_RS07975 (HA248_07955) thrS 1547814..1549757 (+) 1944 WP_000608349.1 threonine--tRNA ligase -
  HA248_RS07980 (HA248_07960) - 1549806..1550780 (-) 975 WP_000887972.1 HAMP domain-containing histidine kinase -
  HA248_RS07985 (HA248_07965) braR 1550773..1551450 (-) 678 WP_000548991.1 response regulator transcription factor Regulator
  HA248_RS07990 (HA248_07970) - 1551606..1552679 (+) 1074 WP_033705533.1 DUF2974 domain-containing protein -
  HA248_RS07995 (HA248_07975) - 1552770..1553072 (-) 303 WP_000281609.1 hypothetical protein -
  HA248_RS08000 (HA248_07980) - 1553140..1553577 (-) 438 WP_001166786.1 Rrf2 family transcriptional regulator -
  HA248_RS08005 (HA248_07985) - 1553653..1554495 (-) 843 WP_000160958.1 metallophosphoesterase -
  HA248_RS08010 (HA248_07990) - 1554607..1555257 (+) 651 WP_033705532.1 metal-dependent transcriptional regulator -
  HA248_RS11890 (HA248_07995) - 1555456..1555987 (+) 532 Protein_1577 nicotinamide mononucleotide transporter -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25936.11 Da        Isoelectric Point: 5.1362

>NTDB_id=377532 HA248_RS07985 WP_000548991.1 1550773..1551450(-) (braR) [Streptococcus pneumoniae strain PZ900701590]
MHKILLVEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=377532 HA248_RS07985 WP_000548991.1 1550773..1551450(-) (braR) [Streptococcus pneumoniae strain PZ900701590]
ATGCACAAGATTTTATTAGTGGAAGATGATCAGGTCATTCGTCAACAGGTCGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCTAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGGGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A501PEF7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

49.083

96.889

0.476
  vicR Streptococcus mutans UA159

35.319

100

0.369

Multiple sequence alignment