Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   FP508_RS01110 Genome accession   NZ_CP041998
Coordinates   188883..189212 (+) Length   109 a.a.
NCBI ID   WP_000793380.1    Uniprot ID   A0A0E1EKJ1
Organism   Streptococcus agalactiae strain GBS7     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 183883..194212
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FP508_RS01095 (FP508_01105) - 186440..186805 (+) 366 WP_000285373.1 DUF1033 family protein -
  FP508_RS01100 (FP508_01115) comYA 186978..187949 (+) 972 WP_000250805.1 competence type IV pilus ATPase ComGA Machinery gene
  FP508_RS01105 (FP508_01120) comYB 187843..188886 (+) 1044 WP_223295889.1 competence type IV pilus assembly protein ComGB Machinery gene
  FP508_RS01110 (FP508_01125) comGC/cglC 188883..189212 (+) 330 WP_000793380.1 competence type IV pilus major pilin ComGC Machinery gene
  FP508_RS01115 (FP508_01130) comYD 189187..189600 (+) 414 WP_000244261.1 competence type IV pilus minor pilin ComGD Machinery gene
  FP508_RS01120 (FP508_01135) comGE 189572..189871 (+) 300 WP_000234804.1 competence type IV pilus minor pilin ComGE -
  FP508_RS01125 (FP508_01140) comGF 189825..190286 (+) 462 WP_001878820.1 competence type IV pilus minor pilin ComGF -
  FP508_RS01130 (FP508_01145) comGG 190264..190635 (+) 372 WP_000601104.1 competence type IV pilus minor pilin ComGG -
  FP508_RS01135 (FP508_01150) comYH 190750..191724 (+) 975 WP_001008574.1 class I SAM-dependent methyltransferase Machinery gene
  FP508_RS01140 (FP508_01155) - 191756..192949 (+) 1194 WP_000047534.1 acetate kinase -
  FP508_RS01145 (FP508_01160) - 193101..193307 (+) 207 WP_000798241.1 helix-turn-helix transcriptional regulator -
  FP508_RS01150 (FP508_01165) - 193366..193503 (+) 138 WP_001865900.1 hypothetical protein -
  FP508_RS01155 (FP508_01170) - 193544..193999 (+) 456 WP_000905673.1 hypothetical protein -

Sequence

Protein


Download         Length: 109 a.a.        Molecular weight: 12129.27 Da        Isoelectric Point: 10.0311

>NTDB_id=375293 FP508_RS01110 WP_000793380.1 188883..189212(+) (comGC/cglC) [Streptococcus agalactiae strain GBS7]
MKNLLLKCKDKKVKAFTLLEMLVVLIIISVLLLLFVPNLSKQKESVTRTGNAAVVKVVESQAELFELQETGRKASLSTLK
SGGYITEKQEKAYLDYYKDSSNGSQKISS

Nucleotide


Download         Length: 330 bp        

>NTDB_id=375293 FP508_RS01110 WP_000793380.1 188883..189212(+) (comGC/cglC) [Streptococcus agalactiae strain GBS7]
ATGAAAAATTTATTGTTAAAATGTAAGGATAAGAAGGTTAAAGCATTTACACTTTTAGAAATGTTAGTTGTTTTGATCAT
TATTTCGGTCTTGTTGTTATTGTTTGTACCCAATTTATCAAAACAAAAGGAAAGTGTCACAAGAACTGGAAATGCCGCTG
TTGTCAAGGTTGTAGAAAGTCAAGCCGAACTTTTTGAACTGCAAGAAACAGGTAGAAAAGCTAGTTTATCCACTCTAAAA
TCTGGAGGATATATTACTGAAAAGCAAGAAAAAGCCTATTTAGATTATTATAAAGACAGTTCCAATGGTTCTCAGAAAAT
TTCAAGTTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E1EKJ1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis NCTC 12261

60.55

100

0.606
  comGC/cglC Streptococcus mitis SK321

59.633

100

0.596
  comYC Streptococcus gordonii str. Challis substr. CH1

61.165

94.495

0.578
  comGC/cglC Streptococcus pneumoniae TIGR4

57.798

100

0.578
  comGC/cglC Streptococcus pneumoniae R6

57.798

100

0.578
  comGC/cglC Streptococcus pneumoniae Rx1

57.798

100

0.578
  comGC/cglC Streptococcus pneumoniae D39

57.798

100

0.578
  comYC Streptococcus mutans UA159

55.238

96.33

0.532
  comYC Streptococcus mutans UA140

55.238

96.33

0.532
  comGC Lactococcus lactis subsp. cremoris KW2

63.043

84.404

0.532
  comYC Streptococcus suis isolate S10

65.854

75.229

0.495

Multiple sequence alignment