Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   FPL13_RS09570 Genome accession   NZ_CP041968
Coordinates   1937656..1938924 (+) Length   422 a.a.
NCBI ID   WP_049514652.1    Uniprot ID   A0A7L8W9X8
Organism   Streptococcus sp. KS 6     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1932656..1943924
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FPL13_RS09555 (FPL13_09700) - 1932870..1933282 (-) 413 Protein_1860 EamA family transporter -
  FPL13_RS09560 (FPL13_09705) - 1933446..1933715 (-) 270 WP_049514649.1 hypothetical protein -
  FPL13_RS09565 (FPL13_09710) - 1933862..1937335 (+) 3474 WP_106388232.1 Cna B-type domain-containing protein -
  FPL13_RS09570 (FPL13_09715) cinA 1937656..1938924 (+) 1269 WP_049514652.1 competence/damage-inducible protein A Machinery gene
  FPL13_RS09575 (FPL13_09720) recA 1938972..1940105 (+) 1134 WP_049514654.1 recombinase RecA Machinery gene
  FPL13_RS09580 (FPL13_09725) spx 1940192..1940590 (+) 399 WP_049514656.1 transcriptional regulator Spx -
  FPL13_RS09585 (FPL13_09730) - 1940673..1941242 (+) 570 WP_049514657.1 SP0191 family lipoprotein -
  FPL13_RS09590 (FPL13_09735) - 1941347..1941904 (+) 558 WP_049514659.1 SP0191 family lipoprotein -
  FPL13_RS09595 (FPL13_09740) - 1942027..1942293 (+) 267 WP_009569646.1 IreB family regulatory phosphoprotein -
  FPL13_RS09600 (FPL13_09745) ruvX 1942293..1942712 (+) 420 WP_049514661.1 Holliday junction resolvase RuvX -
  FPL13_RS09605 (FPL13_09750) - 1942730..1943041 (+) 312 WP_003027765.1 DUF1292 domain-containing protein -

Sequence

Protein


Download         Length: 422 a.a.        Molecular weight: 45573.11 Da        Isoelectric Point: 7.4598

>NTDB_id=375037 FPL13_RS09570 WP_049514652.1 1937656..1938924(+) (cinA) [Streptococcus sp. KS 6]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLASLGVDVYFQTAVGDNKARLLSILEIARNRSNLVILTGGLGPTEDDLTKQT
LSKFLNRRLVFDRMATEKLDRFFASRSDYVRTPNNERQAQIVEGSTPLQNETGLAVGGVIEVSGVTYVVLPGPPSELKPM
VNNELVPLLATGQKLYSRVLRFFGIGESQLVTLLGDLIDNQTDPTIAPYAKTGEVTLRLSTKAGSQKEADVKFAHLEKKI
LAVQTFEKQHLADLFYAYGDDNSLGQTAFELLRRAGKTVTAAESLTAGLFQATLANFAGASNVFSGGFVTYSIEEKSRML
GISLADLGKHGVVSAFTAEKMAEQARKLTASDYAVSLTGVAGPDSLEGHPAGTVYIGLATTEDVQSIKVNIAGRSRTDVR
KIAVLHAFNLLRKTLLKNENML

Nucleotide


Download         Length: 1269 bp        

>NTDB_id=375037 FPL13_RS09570 WP_049514652.1 1937656..1938924(+) (cinA) [Streptococcus sp. KS 6]
ATGAAAGCAGAAATTATTGCTGTGGGTACTGAAATTCTGACAGGTCAGATTGTCAATACAAACGCCCAATTTTTATCTGA
AAAATTAGCGAGTCTGGGAGTAGATGTGTATTTTCAAACTGCGGTCGGAGATAATAAAGCTCGTCTGTTATCCATTTTAG
AAATTGCTCGGAATCGGAGTAATTTGGTCATCTTAACTGGAGGATTAGGCCCAACAGAAGATGACTTGACTAAGCAGACT
TTGTCAAAATTCTTAAATCGTAGATTGGTATTTGACCGAATGGCTACGGAGAAATTGGACCGTTTCTTCGCAAGCAGATC
AGACTATGTGCGAACACCCAATAATGAGCGGCAAGCTCAGATAGTGGAAGGCTCGACTCCTCTCCAAAACGAAACCGGAC
TTGCGGTGGGAGGCGTGATTGAAGTCAGTGGCGTGACTTATGTCGTTCTGCCTGGACCGCCTAGTGAATTAAAACCTATG
GTAAATAATGAGCTGGTTCCGCTTTTAGCAACTGGTCAAAAATTGTATTCAAGAGTTTTGCGTTTCTTTGGTATTGGTGA
AAGTCAATTAGTAACCCTTTTAGGAGATTTAATTGATAATCAGACCGATCCAACCATTGCTCCTTATGCTAAGACGGGAG
AGGTGACATTGCGATTGTCCACTAAGGCTGGCAGTCAAAAGGAAGCAGATGTTAAGTTTGCTCATTTAGAAAAGAAAATT
TTGGCAGTACAGACTTTTGAGAAACAACATTTAGCAGACCTTTTCTACGCTTATGGAGATGATAATTCTCTGGGGCAAAC
AGCTTTTGAACTGCTGAGGAGAGCAGGAAAGACCGTCACAGCAGCTGAAAGTTTGACTGCAGGACTCTTTCAAGCAACTT
TGGCAAACTTTGCTGGAGCCTCAAATGTCTTTAGTGGTGGCTTTGTTACCTACAGTATAGAGGAAAAGAGCCGAATGCTG
GGCATTTCCTTGGCAGACTTGGGAAAGCATGGGGTAGTTTCAGCTTTTACAGCGGAGAAAATGGCAGAGCAGGCAAGAAA
ATTGACCGCTAGTGACTATGCGGTGAGCTTGACAGGTGTGGCAGGTCCAGATAGCTTAGAAGGACATCCAGCAGGGACAG
TTTATATCGGCTTAGCAACCACAGAGGATGTTCAGTCTATTAAGGTTAATATTGCGGGTCGCAGTCGGACAGATGTACGT
AAAATAGCCGTTCTGCATGCTTTCAATTTGCTACGAAAAACTTTGTTAAAAAACGAAAATATGCTATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(263-415)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7L8W9X8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

75.598

99.052

0.749
  cinA Streptococcus mitis NCTC 12261

74.641

99.052

0.739
  cinA Streptococcus pneumoniae Rx1

74.402

99.052

0.737
  cinA Streptococcus pneumoniae R6

74.402

99.052

0.737
  cinA Streptococcus pneumoniae TIGR4

74.402

99.052

0.737
  cinA Streptococcus pneumoniae D39

74.163

99.052

0.735
  cinA Streptococcus mutans UA159

72.34

100

0.725
  cinA Streptococcus suis isolate S10

55.769

98.578

0.55
  cinA Bacillus subtilis subsp. subtilis str. 168

45.694

99.052

0.453

Multiple sequence alignment