Detailed information NTG0375004

Bioinformatically predicted

Overview

• Name: dprA/cilB/dalA
• Type: Machinery gene
• Locus tag: FPL13_RS03595
• Genome accession: NZ_CP041968
• Coordinates: 726299..727141 (+)
• Length: 280 a.a.
• NCBI ID: WP_049513260.1
• Uniprot ID: A0A7L8W9R9
• Organism: Streptococcus sp. KS 6
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 721299..732141

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FPL13_RS03565 (FPL13_03610)	-	721482..722184 (+)	703	Protein_701	acyl-CoA dehydrogenase	-
FPL13_RS03570 (FPL13_03615)	-	722188..723105 (+)	918	WP_049513249.1	MBL fold metallo-hydrolase	-
FPL13_RS03575 (FPL13_03620)	ylqF	723225..724076 (+)	852	WP_049513251.1	ribosome biogenesis GTPase YlqF	-
FPL13_RS03580 (FPL13_03625)	-	724063..724845 (+)	783	WP_049513254.1	ribonuclease HII	-
FPL13_RS03585 (FPL13_03630)	-	724842..725669 (+)	828	WP_049513256.1	PRD domain-containing protein	-
FPL13_RS03590 (FPL13_03635)	-	725659..726216 (+)	558	WP_049513258.1	sugar O-acetyltransferase	-
FPL13_RS03595 (FPL13_03640)	dprA/cilB/dalA	726299..727141 (+)	843	WP_049513260.1	DNA-processing protein DprA	Machinery gene
FPL13_RS03600 (FPL13_03645)	topA	727227..729320 (+)	2094	WP_152907028.1	type I DNA topoisomerase	-
FPL13_RS03605 (FPL13_03650)	-	729384..729881 (+)	498	WP_049513264.1	hypothetical protein	-
FPL13_RS03610 (FPL13_03655)	trmFO	730055..731389 (+)	1335	WP_049513266.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31011.60 Da
• Isoelectric Point: 5.6736

>NTDB_id=375004 FPL13_RS03595 WP_049513260.1 726299..727141(+) (dprA/cilB/dalA) [Streptococcus sp. KS 6]
MDNFDIYKLKEAGLTNQQVINVLSYAEIQEKELSVKDMAVVSECRNPALFIEKYLQLDGDLLCQEFKKFPSFSILDDVYP
WDLSEIYNPPVLLFYKGNLDLLKLPKVAVVGSRNSSRTGSQSVQKIVKELNNELVIVSGLARGIDTSAHMAALQNGGRTI
AVIGTGLDVFYPRANKKLQSYLGEHHLVLSEYGPEAEPLKFHFPERNRIIAGLCRGVIVAEAKMRSGSLITCERAMEEGR
DVFAIPGSILDGRSDGCHHLIQEGAKCVTSGADVLSEFQF

Nucleotide

• Length: 843 bp

>NTDB_id=375004 FPL13_RS03595 WP_049513260.1 726299..727141(+) (dprA/cilB/dalA) [Streptococcus sp. KS 6]
ATGGATAATTTTGATATTTATAAATTAAAAGAAGCCGGCTTGACCAACCAACAGGTCATCAATGTTCTTTCGTATGCTGA
GATACAAGAAAAAGAATTATCAGTAAAAGATATGGCAGTTGTGTCGGAATGCCGTAATCCAGCTCTTTTCATTGAAAAAT
ATCTGCAGCTAGATGGTGATTTATTATGTCAAGAATTTAAAAAATTTCCGTCTTTTTCTATCTTGGATGATGTGTATCCT
TGGGATTTGAGTGAAATTTACAATCCACCCGTTCTCCTTTTCTACAAAGGAAACTTGGATTTGTTAAAATTACCGAAAGT
AGCTGTTGTGGGAAGTCGCAATAGTAGCCGAACAGGCAGTCAATCTGTTCAAAAAATTGTTAAAGAGCTAAACAATGAGC
TAGTTATCGTAAGCGGCTTAGCGCGCGGAATTGATACGTCAGCTCACATGGCAGCGTTGCAAAATGGCGGTCGAACGATT
GCCGTTATTGGAACCGGTTTAGATGTTTTTTATCCAAGAGCAAATAAAAAACTCCAATCGTATTTGGGAGAACATCACCT
TGTGCTTAGTGAATATGGTCCCGAAGCAGAACCATTGAAATTTCATTTTCCAGAACGGAATCGCATTATTGCAGGTTTGT
GTAGGGGCGTTATTGTCGCTGAAGCCAAAATGCGCTCAGGAAGTCTAATTACTTGTGAGCGCGCAATGGAAGAAGGACGA
GATGTGTTTGCTATTCCAGGGTCAATTTTAGACGGCAGAAGTGATGGCTGTCATCATTTGATTCAAGAGGGTGCAAAGTG
CGTCACATCAGGCGCTGACGTACTTTCTGAATTCCAATTTTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-59)

• DNA recombination-mediator protein A (DNA_processg_A) (73-269)

3D structure

• AlphaFold DB: A0A7L8W9R9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	76.429	100	0.764
dprA/cilB/dalA	Streptococcus pneumoniae D39	76.071	100	0.761
dprA/cilB/dalA	Streptococcus pneumoniae R6	76.071	100	0.761
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	76.071	100	0.761
dprA/cilB/dalA	Streptococcus mitis SK321	76.071	100	0.761
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	76.071	100	0.761
dprA	Streptococcus mutans UA159	64.643	100	0.646
dprA	Lactococcus lactis subsp. cremoris KW2	57.857	100	0.579
dprA	Staphylococcus aureus N315	37.943	100	0.382
dprA	Staphylococcus aureus MW2	37.722	100	0.379
dprA	Legionella pneumophila strain ERS1305867	50.739	72.5	0.368