Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   FLL49_RS13305 Genome accession   NZ_CP041344
Coordinates   2617104..2618348 (-) Length   414 a.a.
NCBI ID   WP_033627539.1    Uniprot ID   -
Organism   Enterococcus faecalis strain DM01     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2612104..2623348
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FLL49_RS13280 (FLL49_13280) - 2612574..2612960 (-) 387 WP_002359008.1 RicAFT regulatory complex protein RicA family protein -
  FLL49_RS13285 (FLL49_13285) - 2613034..2613831 (-) 798 WP_002354864.1 TIGR00282 family metallophosphoesterase -
  FLL49_RS13290 (FLL49_13290) rny 2613991..2615547 (-) 1557 WP_002354863.1 ribonuclease Y -
  FLL49_RS13300 (FLL49_13300) recA 2615944..2616990 (-) 1047 WP_002354860.1 recombinase RecA Machinery gene
  FLL49_RS13305 (FLL49_13305) cinA 2617104..2618348 (-) 1245 WP_033627539.1 competence/damage-inducible protein A Machinery gene
  FLL49_RS13310 (FLL49_13310) - 2618540..2619745 (+) 1206 WP_016626354.1 hypothetical protein -
  FLL49_RS13315 (FLL49_13315) - 2619823..2620452 (-) 630 WP_002354854.1 NAD(P)-dependent oxidoreductase -
  FLL49_RS13320 (FLL49_13320) - 2620511..2620936 (-) 426 WP_002383201.1 Rrf2 family transcriptional regulator -
  FLL49_RS13325 (FLL49_13325) - 2621025..2621408 (-) 384 WP_002358999.1 YccF domain-containing protein -
  FLL49_RS13330 (FLL49_13330) - 2621572..2622363 (+) 792 WP_016626353.1 hypothetical protein -

Sequence

Protein


Download         Length: 414 a.a.        Molecular weight: 45110.26 Da        Isoelectric Point: 4.6585

>NTDB_id=371378 FLL49_RS13305 WP_033627539.1 2617104..2618348(-) (cinA) [Enterococcus faecalis strain DM01]
MKAEIIAVGTELLLGQVVNTNATFLSVELAALGIDVYYQTVVGDNGGRLETLLTEAEQRSDLIVLCGGLGPTEDDLTKQV
VAQHLHKSLVEDQEGLNRLHQFFQQSKRPMTENNLRQVLAIEGGQVLQNPTGLAVGSFVTEGTTSYLLLPGPPNELIPMF
QQAARPLLIDAFPQEEQLISRVLRFYGIGESQLVTEIQSLIAHQTNPTIAPYAKPNEVTLRLTVKTKDLVAGEELLTATE
EKVLAKVGDYFYGYGDDNSLAKVTVDLLLQNGQTVTAAESLTAGLFQSTLGEIAGASKIFKGGFVTYSQETKENFLGISH
ELLEEHGTVSEACAKEMAEKACQLAKSNYGLSFTGVAGDPIEGQPTGTVWIGLAEEGQPTVAECFHFNRDRNYIRQSAVM
RGLDLLRRRIINKK

Nucleotide


Download         Length: 1245 bp        

>NTDB_id=371378 FLL49_RS13305 WP_033627539.1 2617104..2618348(-) (cinA) [Enterococcus faecalis strain DM01]
ATGAAAGCAGAAATCATTGCAGTCGGAACAGAGTTATTACTGGGACAAGTAGTGAATACCAACGCCACCTTTTTATCAGT
AGAGTTAGCTGCGCTAGGCATCGATGTTTACTATCAGACCGTTGTTGGCGATAACGGCGGCCGCTTAGAAACGCTACTAA
CAGAAGCAGAACAAAGAAGTGATTTAATTGTCCTTTGTGGAGGGCTAGGACCTACAGAAGACGATTTAACCAAGCAAGTT
GTCGCACAACATCTCCATAAATCATTAGTAGAAGATCAAGAAGGATTGAACCGCTTACACCAGTTTTTCCAACAGTCTAA
GCGGCCAATGACGGAAAATAATCTACGACAAGTGTTAGCCATTGAAGGTGGACAAGTTCTTCAAAACCCGACAGGATTAG
CGGTTGGTTCTTTCGTAACAGAAGGGACAACAAGCTATTTGCTCTTACCAGGGCCGCCCAATGAATTAATTCCGATGTTC
CAACAAGCGGCACGACCTTTATTGATTGATGCGTTTCCACAAGAAGAACAATTGATTTCAAGAGTCTTGCGTTTTTATGG
CATTGGTGAATCCCAGCTGGTGACCGAGATTCAATCGTTGATTGCGCACCAAACGAATCCAACCATTGCGCCTTATGCTA
AGCCTAATGAAGTGACACTTCGTTTAACAGTTAAAACAAAAGACTTAGTAGCTGGCGAAGAATTATTAACAGCGACGGAA
GAAAAGGTTTTAGCTAAAGTGGGAGACTATTTTTATGGGTATGGGGATGACAATAGTTTAGCCAAGGTAACAGTGGATTT
GTTATTACAAAACGGACAAACCGTCACGGCTGCTGAGAGCCTCACCGCTGGCCTATTCCAAAGTACACTGGGGGAAATTG
CGGGTGCTTCGAAGATTTTTAAGGGAGGCTTCGTGACGTATTCGCAAGAAACAAAAGAGAACTTTTTAGGAATTTCTCAT
GAACTTTTAGAAGAACATGGCACGGTAAGTGAAGCGTGTGCCAAAGAAATGGCAGAGAAAGCGTGTCAGTTAGCTAAATC
TAACTATGGTTTATCATTTACTGGGGTCGCTGGTGACCCAATCGAAGGTCAACCGACAGGCACTGTTTGGATTGGGCTGG
CGGAAGAAGGCCAACCAACCGTTGCAGAATGTTTCCATTTTAACCGTGACCGAAATTATATTAGACAGAGTGCGGTTATG
CGAGGGTTAGATCTTTTGCGGCGCCGAATCATTAATAAAAAATAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-168)

Competence-damaged protein (CinA)

(258-409)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

51.914

100

0.524
  cinA Streptococcus mitis SK321

51.064

100

0.522
  cinA Streptococcus mitis NCTC 12261

50.827

100

0.519
  cinA Streptococcus pneumoniae TIGR4

50.118

100

0.512
  cinA Streptococcus pneumoniae D39

49.882

100

0.51
  cinA Streptococcus pneumoniae Rx1

49.645

100

0.507
  cinA Streptococcus pneumoniae R6

49.645

100

0.507
  cinA Bacillus subtilis subsp. subtilis str. 168

48.522

98.068

0.476
  cinA Streptococcus suis isolate S10

43.584

99.758

0.435

Multiple sequence alignment