Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   AhaeAN54_RS16405 Genome accession   NZ_CP041224
Coordinates   3345272..3346498 (+) Length   408 a.a.
NCBI ID   WP_005083853.1    Uniprot ID   N9GGD8
Organism   Acinetobacter haemolyticus strain AN54     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 3340272..3351498
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AhaeAN54_RS16375 (AhaeAN54_016375) rimP 3341027..3341551 (-) 525 WP_005083847.1 ribosome maturation factor RimP -
  AhaeAN54_RS16390 (AhaeAN54_016390) secG 3342023..3342352 (-) 330 WP_004637686.1 preprotein translocase subunit SecG -
  AhaeAN54_RS16395 (AhaeAN54_016395) tpiA 3342365..3343156 (-) 792 WP_005088004.1 triose-phosphate isomerase -
  AhaeAN54_RS16400 (AhaeAN54_016400) pilB 3343532..3345247 (+) 1716 Protein_3189 type IV-A pilus assembly ATPase PilB -
  AhaeAN54_RS16405 (AhaeAN54_016405) pilC 3345272..3346498 (+) 1227 WP_005083853.1 type II secretion system F family protein Machinery gene
  AhaeAN54_RS16410 (AhaeAN54_016410) pilD 3346498..3347358 (+) 861 WP_005083855.1 prepilin peptidase Machinery gene
  AhaeAN54_RS16415 (AhaeAN54_016415) coaE 3347360..3347965 (+) 606 WP_005088002.1 dephospho-CoA kinase -
  AhaeAN54_RS16420 (AhaeAN54_016420) - 3347962..3348873 (-) 912 WP_017394516.1 DMT family transporter -
  AhaeAN54_RS16430 (AhaeAN54_016430) rlmB 3348913..3349659 (-) 747 WP_004637678.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  AhaeAN54_RS16435 (AhaeAN54_016435) - 3349768..3350094 (-) 327 WP_004637677.1 pyrimidine/purine nucleoside phosphorylase -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 44933.40 Da        Isoelectric Point: 9.7764

>NTDB_id=370691 AhaeAN54_RS16405 WP_005083853.1 3345272..3346498(+) (pilC) [Acinetobacter haemolyticus strain AN54]
MAAKKAQMMPTFAYEGVDRKGAKIKGELPARNMALAKVTLRKQGVTIKNIREKRKNILEGLMKKKVTTLDITVFTRQLAT
MMKAGVPLVQGFEIVAEGLENPSMREVVLGLKGEVEGGNTFAGALRKYPQYFDNLFCSLVESGEQSGALETMLDRVAIYK
EKSELLKQKIKKAMKYPATVIVVAVIVTIILMVKVVPVFQDLFSSFGADLPAFTKMVVNMSVWMQEYWFILIIVVGAIIA
CFLEAKKRSKKFRDTLDKLALRLPIFGDLVYKAIIARYSRTLATTFAAGVPLIDALESTAGATNNVVYEEAVMKIREDVA
TGQQLQFAMRVSNRFPSMAIQMVAIGEESGALDSMLDKVATHFENEVDNAVDGLTAMMEPLIMAILGVLVGGLVIAMYLP
IFQMGSVV

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=370691 AhaeAN54_RS16405 WP_005083853.1 3345272..3346498(+) (pilC) [Acinetobacter haemolyticus strain AN54]
ATGGCAGCTAAAAAAGCGCAAATGATGCCTACTTTTGCTTACGAAGGGGTAGATCGCAAAGGGGCAAAAATTAAAGGGGA
ATTACCAGCACGTAATATGGCTTTAGCCAAAGTCACATTACGCAAACAAGGGGTAACGATTAAAAACATTCGAGAAAAAC
GCAAAAACATTCTTGAAGGTTTGATGAAGAAGAAAGTCACCACCCTTGATATCACGGTATTTACACGCCAACTGGCAACC
ATGATGAAAGCTGGTGTCCCACTCGTGCAAGGCTTTGAAATCGTGGCTGAAGGTTTAGAGAATCCATCGATGCGGGAAGT
GGTACTTGGACTCAAAGGCGAAGTTGAAGGCGGTAATACCTTTGCGGGCGCATTAAGAAAATACCCACAATACTTTGACA
ACCTCTTTTGCTCTTTAGTTGAATCTGGTGAACAATCTGGTGCACTAGAAACCATGCTAGATCGCGTCGCGATTTATAAA
GAGAAAAGTGAGTTACTCAAACAAAAAATCAAAAAAGCCATGAAATATCCTGCGACAGTTATCGTGGTTGCAGTGATTGT
CACCATTATTTTGATGGTCAAGGTAGTCCCTGTTTTCCAAGATCTATTTAGCTCATTTGGTGCAGATTTACCTGCTTTTA
CCAAAATGGTCGTGAATATGTCCGTTTGGATGCAAGAATATTGGTTTATTTTAATTATCGTTGTCGGTGCGATTATTGCC
TGTTTTCTTGAAGCAAAAAAACGTAGTAAAAAATTCCGCGACACTCTTGATAAACTTGCATTACGCTTACCGATTTTTGG
TGATTTAGTTTATAAAGCCATTATTGCGCGTTATAGTCGTACACTTGCAACAACATTTGCAGCAGGGGTTCCATTGATTG
ATGCACTCGAATCAACGGCTGGTGCAACCAATAACGTTGTTTATGAAGAAGCCGTGATGAAAATTCGTGAAGATGTTGCT
ACAGGACAACAGTTACAATTTGCCATGCGTGTTTCTAATCGCTTTCCATCAATGGCGATTCAAATGGTCGCAATTGGTGA
AGAATCAGGTGCTTTAGATAGTATGCTTGATAAAGTTGCCACTCACTTCGAAAATGAAGTCGACAATGCGGTCGATGGCT
TAACCGCAATGATGGAGCCATTAATTATGGCAATTCTAGGAGTACTTGTGGGTGGTCTTGTTATCGCAATGTACCTTCCA
ATTTTCCAAATGGGCTCTGTGGTCTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(74-197)

Type II secretion system (T2SS), protein F (T2SSF)

(279-400)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB N9GGD8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Acinetobacter baumannii D1279779

92.647

100

0.926
  pilC Acinetobacter baylyi ADP1

86.275

100

0.863
  pilC Pseudomonas stutzeri DSM 10701

61.425

99.755

0.613
  pilC Legionella pneumophila strain ERS1305867

52.84

99.265

0.525
  pilG Neisseria meningitidis 44/76-A

46.734

97.549

0.456
  pilG Neisseria gonorrhoeae MS11

46.734

97.549

0.456
  pilC Vibrio cholerae strain A1552

41.278

99.755

0.412
  pilC Vibrio campbellii strain DS40M4

40.342

100

0.404
  pilC Thermus thermophilus HB27

37.157

98.284

0.365

Multiple sequence alignment