Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   FKM99_RS23025 Genome accession   NZ_CP041202
Coordinates   2845116..2846339 (+) Length   407 a.a.
NCBI ID   WP_005479682.1    Uniprot ID   Q87LT6
Organism   Vibrio parahaemolyticus strain Vb0624     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2840116..2851339
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FKM99_RS23005 (FKM99_23005) ampD 2841179..2841730 (-) 552 WP_005462574.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  FKM99_RS23010 (FKM99_23010) nadC 2841823..2842710 (+) 888 WP_141180406.1 carboxylating nicotinate-nucleotide diphosphorylase -
  FKM99_RS23015 (FKM99_23015) - 2842973..2843407 (+) 435 WP_025501252.1 type IV pilin protein -
  FKM99_RS23020 (FKM99_23020) pilB 2843407..2845092 (+) 1686 WP_141180407.1 type IV-A pilus assembly ATPase PilB Machinery gene
  FKM99_RS23025 (FKM99_23025) pilC 2845116..2846339 (+) 1224 WP_005479682.1 type II secretion system F family protein Machinery gene
  FKM99_RS23030 (FKM99_23030) pilD 2846404..2847273 (+) 870 WP_141180408.1 A24 family peptidase Machinery gene
  FKM99_RS23035 (FKM99_23035) coaE 2847274..2847888 (+) 615 WP_141180409.1 dephospho-CoA kinase -
  FKM99_RS23040 (FKM99_23040) zapD 2847916..2848656 (+) 741 WP_023624252.1 cell division protein ZapD -
  FKM99_RS23045 (FKM99_23045) yacG 2848725..2848919 (+) 195 WP_005462546.1 DNA gyrase inhibitor YacG -
  FKM99_RS23050 (FKM99_23050) rplS 2849249..2849602 (-) 354 WP_005462554.1 50S ribosomal protein L19 -
  FKM99_RS23055 (FKM99_23055) trmD 2849644..2850387 (-) 744 WP_141180410.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  FKM99_RS23060 (FKM99_23060) rimM 2850415..2850963 (-) 549 WP_005462552.1 ribosome maturation factor RimM -
  FKM99_RS23065 (FKM99_23065) rpsP 2850992..2851240 (-) 249 WP_005379962.1 30S ribosomal protein S16 -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 45220.39 Da        Isoelectric Point: 10.4368

>NTDB_id=370461 FKM99_RS23025 WP_005479682.1 2845116..2846339(+) (pilC) [Vibrio parahaemolyticus strain Vb0624]
MKTTTPQLKNFRWKGVNSSGKKTSGQTLAMSEIEVRERLDAQHIKIKKLKKSSISFLTKLSHRVKGKDITVFTRQISTML
VTGVPLVQALKLVSDNHKKAEMKSILMSVTRAVEAGTPMSKAMRTASNHFDPLYTDLIATGEQSGNLAEVFERLATYREK
NEQLRAKVIKALIYPAMVILVALGVSFIMLTKVIPEFEKMFVGFGAELPWFTRQVLDLSAWTQNWSPFIALGSISVFISA
RVLSKRSDSFRLMLNRSVLKFPVLGAVLSKAAIAKFSRTLATSFTAGIPILTSLKTTSKTSGNMHYQLAIEEVYRDTAAG
MPMYVAMRNCNVFPELVLQMVMIGEESGRLDDMLNKVATIYEFEVDNTVDNLSKILEPLIIVFLGIVVGGLVTAMYLPIF
NLMSVLG

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=370461 FKM99_RS23025 WP_005479682.1 2845116..2846339(+) (pilC) [Vibrio parahaemolyticus strain Vb0624]
ATGAAAACTACGACACCACAATTAAAGAACTTCCGTTGGAAAGGCGTCAACAGCTCAGGGAAAAAGACCTCTGGTCAAAC
TCTGGCAATGAGCGAAATCGAAGTACGAGAGCGCTTAGATGCCCAGCACATCAAAATCAAAAAGCTAAAGAAAAGCAGCA
TCTCTTTTTTGACCAAACTTAGCCATCGCGTAAAAGGGAAAGACATCACGGTTTTCACTCGTCAAATCTCAACGATGCTG
GTAACCGGTGTGCCGCTAGTACAAGCATTGAAATTGGTCTCTGATAACCACAAAAAAGCGGAAATGAAATCCATTTTGAT
GAGTGTAACTCGGGCTGTTGAAGCGGGTACGCCGATGTCCAAAGCGATGCGTACCGCCAGTAACCATTTTGACCCGCTGT
ATACCGACCTGATTGCGACAGGAGAACAATCGGGCAACTTAGCCGAAGTGTTCGAACGCTTAGCCACCTACAGGGAAAAA
AATGAGCAGCTTAGAGCCAAAGTGATCAAGGCTCTAATATATCCAGCCATGGTTATTCTAGTTGCACTGGGAGTATCGTT
TATCATGCTAACCAAGGTCATTCCCGAGTTTGAAAAAATGTTTGTTGGCTTTGGTGCTGAACTGCCATGGTTTACAAGGC
AAGTCTTAGATCTTTCCGCTTGGACACAAAACTGGAGCCCATTTATCGCACTTGGCTCCATCAGTGTATTTATCTCCGCG
AGAGTACTCTCTAAGCGTTCAGATTCTTTTCGTTTAATGCTCAACCGATCTGTACTTAAGTTTCCAGTCCTTGGGGCAGT
TTTATCGAAAGCCGCTATCGCAAAATTTAGTCGAACACTCGCTACGAGCTTTACGGCGGGCATTCCGATTCTAACCAGTT
TAAAAACCACCTCGAAAACGTCCGGAAATATGCATTATCAATTGGCTATCGAAGAGGTTTATCGCGATACCGCAGCAGGA
ATGCCGATGTATGTTGCAATGCGCAATTGCAACGTGTTCCCTGAGTTGGTGCTGCAAATGGTTATGATAGGCGAAGAATC
CGGCCGACTTGACGATATGCTCAATAAAGTTGCCACAATTTACGAGTTTGAAGTGGACAACACCGTCGATAACCTCAGTA
AAATCTTAGAGCCATTGATTATCGTTTTTTTAGGTATCGTTGTCGGTGGCTTGGTCACAGCAATGTACTTGCCAATCTTT
AACTTAATGAGTGTATTGGGCTAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(276-398)

Type II secretion system (T2SS), protein F (T2SSF)

(72-195)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q87LT6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Vibrio campbellii strain DS40M4

85.995

100

0.86
  pilC Vibrio cholerae strain A1552

74.321

99.509

0.74
  pilC Acinetobacter baylyi ADP1

42.75

98.28

0.42
  pilC Acinetobacter baumannii D1279779

41.439

99.017

0.41
  pilG Neisseria gonorrhoeae MS11

40.494

99.509

0.403
  pilG Neisseria meningitidis 44/76-A

40.247

99.509

0.4
  pilC Pseudomonas stutzeri DSM 10701

40.909

97.297

0.398
  pilC Legionella pneumophila strain ERS1305867

39.803

100

0.398

Multiple sequence alignment