Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   SLIT_RS13480 Genome accession   NC_013959
Coordinates   2730498..2731715 (+) Length   405 a.a.
NCBI ID   WP_013030822.1    Uniprot ID   D5CP03
Organism   Sideroxydans lithotrophicus ES-1     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2725498..2736715
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SLIT_RS13460 (Slit_2695) - 2725634..2726254 (-) 621 WP_013030818.1 ParA family protein -
  SLIT_RS13465 (Slit_2696) ilvD 2726285..2728135 (-) 1851 WP_013030819.1 dihydroxy-acid dehydratase -
  SLIT_RS13470 (Slit_2697) lgt 2728201..2729004 (+) 804 WP_013030820.1 prolipoprotein diacylglyceryl transferase -
  SLIT_RS13475 (Slit_2698) - 2729101..2730393 (+) 1293 WP_013030821.1 HlyC/CorC family transporter -
  SLIT_RS13480 (Slit_2699) pilC 2730498..2731715 (+) 1218 WP_013030822.1 type II secretion system F family protein Machinery gene
  SLIT_RS13485 (Slit_2700) pilD 2731806..2732639 (+) 834 WP_317623665.1 A24 family peptidase Machinery gene
  SLIT_RS13490 (Slit_2701) coaE 2732636..2733247 (+) 612 WP_013030824.1 dephospho-CoA kinase -
  SLIT_RS13495 (Slit_2702) zapD 2733309..2734067 (+) 759 WP_013030825.1 cell division protein ZapD -
  SLIT_RS13500 (Slit_2703) - 2734064..2734249 (+) 186 WP_013030826.1 DNA gyrase inhibitor YacG -
  SLIT_RS13505 (Slit_2704) - 2734237..2735175 (-) 939 WP_013030827.1 Nudix family hydrolase -
  SLIT_RS13510 (Slit_2705) - 2735162..2736025 (-) 864 WP_013030828.1 ATP-binding protein -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 43948.44 Da        Isoelectric Point: 9.4614

>NTDB_id=36747 SLIT_RS13480 WP_013030822.1 2730498..2731715(+) (pilC) [Sideroxydans lithotrophicus ES-1]
MATARSEKTKEQQYTWEGKDKAGKAVKGEMRGAGEASVSAHLRRQGITVTKIKKSSTGRGKVTEKDITLFTRQLATMLKS
GVPLLQAFDIVGKGHDNPAVSRLLFDIKTDVETGSSLEQSFRKFPLYFDDLYCNLLGAGEAAGILDSLLDRLATYKEKIL
AIKSKIKSALFYPISIIVIAFVITAVIMIFVIPAFKDLFSNFGADLPGPTLVVMAISDFFVAWWWAIFGGVGGAVYGFFY
AWKRNKTMQRRMDQLMLKIPVFGPLVRKASIARWSRTLATMFAAGVPLVEAFDSVAGAAGNAVYYDATKAIQREVTSGTS
LTVAMQNTDAFPSMVLQMVAIGEESGALDAMLGKVADFFEAEVDDAVEALSSLMEPVIMVVLGTLIGGMVVAMYLPIFKM
GQAVG

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=36747 SLIT_RS13480 WP_013030822.1 2730498..2731715(+) (pilC) [Sideroxydans lithotrophicus ES-1]
ATGGCTACAGCAAGATCTGAAAAAACTAAAGAACAACAATATACCTGGGAAGGCAAGGATAAGGCTGGTAAAGCCGTCAA
AGGCGAGATGCGCGGTGCGGGCGAGGCAAGCGTTTCCGCACACCTGCGCCGCCAGGGCATCACCGTCACCAAGATCAAGA
AGAGTTCCACTGGCCGCGGCAAAGTCACCGAGAAAGATATCACACTGTTCACACGCCAACTGGCCACCATGCTGAAGTCG
GGCGTACCCCTGCTGCAAGCCTTCGATATCGTCGGCAAAGGTCATGACAATCCTGCCGTCTCACGCTTGCTGTTCGACAT
CAAAACCGACGTGGAGACCGGCAGCAGTCTGGAACAGTCGTTCCGCAAATTCCCGCTGTATTTTGACGACCTGTATTGCA
ATTTGCTCGGCGCTGGCGAAGCAGCCGGTATCCTGGACAGCCTGCTTGACCGCCTGGCGACCTACAAGGAAAAGATCCTT
GCCATCAAGAGCAAGATCAAGTCCGCGCTGTTCTATCCGATCTCCATCATCGTCATCGCTTTTGTGATTACCGCAGTCAT
CATGATCTTCGTGATTCCGGCGTTCAAAGATCTTTTCTCCAATTTTGGCGCAGACCTTCCCGGTCCTACGCTGGTCGTGA
TGGCCATTTCCGATTTCTTCGTGGCTTGGTGGTGGGCGATATTCGGCGGGGTCGGCGGAGCCGTGTACGGATTTTTCTAC
GCCTGGAAGCGCAACAAGACCATGCAACGGCGCATGGATCAGTTGATGCTCAAGATCCCGGTGTTCGGCCCGCTGGTACG
CAAGGCTTCCATCGCACGCTGGTCGCGCACCCTGGCCACCATGTTTGCAGCTGGCGTGCCATTGGTCGAAGCGTTTGATT
CGGTAGCAGGCGCCGCAGGTAATGCGGTCTATTACGACGCGACCAAGGCCATTCAGCGTGAGGTGACTTCAGGTACCAGC
CTCACTGTCGCCATGCAAAATACCGATGCCTTCCCCAGCATGGTGTTGCAGATGGTGGCCATCGGCGAAGAATCCGGCGC
GCTGGACGCGATGCTCGGCAAGGTGGCCGATTTCTTCGAGGCGGAAGTCGACGATGCAGTCGAAGCGCTGTCCAGCCTGA
TGGAGCCAGTCATCATGGTGGTACTGGGCACGCTGATTGGCGGCATGGTGGTAGCCATGTATTTGCCGATCTTCAAAATG
GGCCAGGCCGTCGGCTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(274-396)

Type II secretion system (T2SS), protein F (T2SSF)

(70-193)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB D5CP03

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Legionella pneumophila strain ERS1305867

53.788

97.778

0.526
  pilC Pseudomonas stutzeri DSM 10701

53.133

98.519

0.523
  pilG Neisseria gonorrhoeae MS11

51.378

98.519

0.506
  pilG Neisseria meningitidis 44/76-A

50.627

98.519

0.499
  pilC Acinetobacter baumannii D1279779

49.118

98.025

0.481
  pilC Acinetobacter baylyi ADP1

48.866

98.025

0.479
  pilC Vibrio cholerae strain A1552

40.852

98.519

0.402
  pilC Vibrio campbellii strain DS40M4

38.235

100

0.385
  pilC Thermus thermophilus HB27

37.656

99.012

0.373

Multiple sequence alignment