Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   FED53_RS06665 Genome accession   NZ_CP040367
Coordinates   1174382..1175620 (+) Length   412 a.a.
NCBI ID   WP_138116701.1    Uniprot ID   -
Organism   Priestia flexa isolate 1-2-1     
Function   unknown (predicted from homology)   
Unclear

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1161495..1206806 1174382..1175620 within 0


Gene organization within MGE regions


Location: 1161495..1206806
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FED53_RS06605 (FED53_06605) - 1161639..1162364 (+) 726 WP_025908584.1 GntR family transcriptional regulator -
  FED53_RS06610 (FED53_06610) - 1162493..1163572 (+) 1080 WP_100346939.1 BMP family lipoprotein -
  FED53_RS06615 (FED53_06615) - 1163698..1165227 (+) 1530 WP_100346940.1 ABC transporter ATP-binding protein -
  FED53_RS06620 (FED53_06620) - 1165221..1166282 (+) 1062 WP_025908587.1 ABC transporter permease -
  FED53_RS06625 (FED53_06625) - 1166279..1167238 (+) 960 WP_025908588.1 ABC transporter permease -
  FED53_RS06630 (FED53_06630) yfmF 1167862..1169157 (+) 1296 WP_138116700.1 EF-P 5-aminopentanol modification-associated protein YfmF -
  FED53_RS06635 (FED53_06635) yfmH 1169144..1170427 (+) 1284 WP_025908590.1 EF-P 5-aminopentanol modification-associated protein YfmH -
  FED53_RS06640 (FED53_06640) ymfI 1170498..1171223 (+) 726 WP_061785725.1 elongation factor P 5-aminopentanone reductase -
  FED53_RS06645 (FED53_06645) - 1171290..1171550 (+) 261 WP_061785726.1 DUF3243 domain-containing protein -
  FED53_RS06650 (FED53_06650) - 1171930..1172736 (+) 807 WP_090752669.1 DUF3388 domain-containing protein -
  FED53_RS06655 (FED53_06655) - 1172749..1173696 (+) 948 WP_225002363.1 helix-turn-helix domain-containing protein -
  FED53_RS06660 (FED53_06660) pgsA 1173784..1174368 (+) 585 WP_025908595.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  FED53_RS06665 (FED53_06665) cinA 1174382..1175620 (+) 1239 WP_138116701.1 competence/damage-inducible protein A Machinery gene
  FED53_RS06670 (FED53_06670) recA 1175873..1176910 (+) 1038 WP_025908597.1 recombinase RecA Machinery gene
  FED53_RS06675 (FED53_06675) rny 1177192..1178751 (+) 1560 WP_025908598.1 ribonuclease Y -
  FED53_RS06680 (FED53_06680) - 1178811..1179608 (+) 798 WP_025908599.1 TIGR00282 family metallophosphoesterase -
  FED53_RS06685 (FED53_06685) spoVS 1179843..1180103 (+) 261 WP_003181955.1 stage V sporulation protein SpoVS -
  FED53_RS06690 (FED53_06690) - 1180182..1181096 (+) 915 WP_061785728.1 dipeptidase -
  FED53_RS06695 (FED53_06695) - 1181276..1183033 (+) 1758 WP_025908601.1 2-oxoacid:acceptor oxidoreductase subunit alpha -
  FED53_RS06700 (FED53_06700) - 1183020..1183886 (+) 867 WP_025908602.1 2-oxoacid:ferredoxin oxidoreductase subunit beta -
  FED53_RS06705 (FED53_06705) tdh 1184336..1185379 (+) 1044 WP_078989382.1 L-threonine 3-dehydrogenase -
  FED53_RS06710 (FED53_06710) - 1185399..1186577 (+) 1179 WP_138116702.1 glycine C-acetyltransferase -
  FED53_RS06715 (FED53_06715) miaB 1186807..1188336 (+) 1530 WP_025908606.1 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB -
  FED53_RS06720 (FED53_06720) - 1188338..1188769 (+) 432 WP_061785716.1 RicAFT regulatory complex protein RicA family protein -
  FED53_RS06725 (FED53_06725) - 1188968..1189513 (+) 546 WP_025908608.1 outer spore coat protein CotE -
  FED53_RS06730 (FED53_06730) mutS 1189650..1192298 (+) 2649 WP_138116703.1 DNA mismatch repair protein MutS -
  FED53_RS06735 (FED53_06735) mutL 1192318..1194219 (+) 1902 WP_138116704.1 DNA mismatch repair endonuclease MutL -
  FED53_RS06740 (FED53_06740) - 1194458..1194976 (+) 519 WP_138116705.1 hypothetical protein -
  FED53_RS06745 (FED53_06745) miaA 1195419..1196369 (+) 951 WP_076513904.1 tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA -
  FED53_RS06750 (FED53_06750) hfq 1196404..1196628 (+) 225 WP_025908613.1 RNA chaperone Hfq -
  FED53_RS06755 (FED53_06755) spoVK 1196884..1197819 (+) 936 WP_237071984.1 stage V sporulation protein K -
  FED53_RS06760 (FED53_06760) - 1197850..1198461 (-) 612 WP_061785712.1 trimeric intracellular cation channel family protein -
  FED53_RS06765 (FED53_06765) hflX 1198712..1199974 (+) 1263 WP_025908616.1 GTPase HflX -
  FED53_RS06770 (FED53_06770) - 1199990..1201252 (+) 1263 WP_025908617.1 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme -
  FED53_RS06775 (FED53_06775) - 1201445..1201867 (+) 423 WP_025908618.1 MerR family transcriptional regulator -
  FED53_RS06780 (FED53_06780) glnA 1201949..1203283 (+) 1335 WP_025908619.1 type I glutamate--ammonia ligase -
  FED53_RS06785 (FED53_06785) - 1203386..1204576 (-) 1191 WP_025908620.1 tyrosine-type recombinase/integrase -
  FED53_RS06790 (FED53_06790) - 1204589..1205101 (-) 513 WP_062686188.1 ImmA/IrrE family metallo-endopeptidase -
  FED53_RS06795 (FED53_06795) - 1205182..1205775 (-) 594 WP_138116706.1 hypothetical protein -
  FED53_RS06800 (FED53_06800) - 1205789..1206415 (-) 627 WP_138116707.1 hypothetical protein -

Sequence

Protein


Download         Length: 412 a.a.        Molecular weight: 45001.32 Da        Isoelectric Point: 4.9402

>NTDB_id=363692 FED53_RS06665 WP_138116701.1 1174382..1175620(+) (cinA) [Priestia flexa isolate 1-2-1]
MNAEIIGVGSELLLGQIANTNAQYLSKKFAELGINVYYHTVVGDNESRLKEAILTAKKRADLIVFTGGLGPTKDDLTKET
IASELGVPLVTDQQALESIEAYFEKTNRTMTPNNRKQAIVLEGATILPNDYGMAPGMGITVHGIHYMLFPGPPKELYPMY
ESYGQAYLAEKLDMKEQIESRVLRFFGIGESQLETDIEDLLDAQTNPTIAPLAADGEVTLRLTAKHGDVVEAHRMLDEVE
KQIMSRVGEFFYGYDMTSLQAELIATMREQEVTVASAESLTGGLFSGTLTSIPGAGDVVKGSIVAYHTEVKHNVLHVAKE
TLEQDGAVSERCAEEMAVGVKKLTGSDVGISFTGVAGPSKQEGKEVGTVYIGIAFKNEKTRVYSLKLTGSRDGIRKRTVN
YGIYYLLQLLKQ

Nucleotide


Download         Length: 1239 bp        

>NTDB_id=363692 FED53_RS06665 WP_138116701.1 1174382..1175620(+) (cinA) [Priestia flexa isolate 1-2-1]
ATGAACGCGGAAATTATTGGAGTAGGTTCAGAGCTTTTGCTAGGCCAAATTGCCAATACAAACGCGCAATACCTATCTAA
AAAGTTTGCAGAGCTTGGTATTAACGTATATTATCATACGGTAGTTGGGGATAATGAAAGCCGATTGAAAGAAGCAATTT
TGACCGCCAAAAAACGTGCGGATTTGATTGTGTTTACAGGTGGGCTTGGGCCAACCAAAGATGACCTTACAAAAGAAACA
ATTGCTTCAGAACTAGGTGTCCCACTTGTAACAGATCAGCAAGCGCTTGAAAGTATCGAAGCGTATTTCGAAAAAACGAA
TCGGACAATGACGCCTAATAATAGGAAGCAAGCAATTGTACTTGAAGGTGCAACAATACTGCCAAACGATTATGGAATGG
CACCAGGAATGGGCATTACGGTGCATGGTATTCACTACATGTTATTTCCTGGTCCACCAAAGGAACTTTACCCTATGTAT
GAATCGTATGGACAAGCATATTTAGCAGAAAAGCTAGATATGAAAGAGCAAATTGAATCTCGCGTTTTACGTTTCTTTGG
AATTGGAGAGTCTCAGTTAGAAACAGATATTGAGGATTTATTAGATGCACAAACAAACCCAACCATTGCGCCGTTAGCTG
CTGATGGAGAAGTAACGCTTCGCTTAACGGCTAAGCATGGAGATGTGGTTGAGGCTCATCGAATGCTTGATGAAGTAGAA
AAGCAGATTATGAGCCGTGTAGGAGAGTTTTTCTACGGATACGATATGACATCTCTACAGGCTGAACTCATTGCTACAAT
GCGAGAGCAAGAAGTGACCGTTGCTTCAGCTGAAAGTTTAACTGGCGGATTGTTTAGTGGGACGCTAACGAGCATTCCTG
GAGCTGGAGATGTTGTAAAAGGTAGCATTGTTGCTTATCACACTGAGGTAAAGCACAATGTGCTACATGTAGCAAAAGAA
ACCCTAGAGCAAGACGGGGCAGTTAGCGAGAGATGCGCAGAAGAAATGGCTGTTGGTGTGAAAAAGCTGACAGGCTCTGA
TGTTGGTATTAGCTTTACAGGCGTCGCTGGTCCGTCTAAGCAAGAAGGTAAAGAAGTTGGTACAGTTTACATTGGTATAG
CTTTTAAAAATGAAAAAACACGCGTGTATTCGCTAAAGCTTACAGGCAGTCGTGATGGTATCCGTAAACGCACTGTGAAT
TATGGAATTTATTATCTTTTACAACTATTGAAACAGTAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(257-409)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-165)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Bacillus subtilis subsp. subtilis str. 168

61.463

99.515

0.612
  cinA Streptococcus mitis SK321

46.247

100

0.464
  cinA Streptococcus pneumoniae TIGR4

46.247

100

0.464
  cinA Streptococcus mitis NCTC 12261

46.005

100

0.461
  cinA Streptococcus pneumoniae Rx1

45.763

100

0.459
  cinA Streptococcus pneumoniae R6

45.763

100

0.459
  cinA Streptococcus pneumoniae D39

45.521

100

0.456
  cinA Streptococcus mutans UA159

44.686

100

0.449

Multiple sequence alignment