Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   GALLO_RS03605 Genome accession   NC_013798
Coordinates   683703..684368 (+) Length   221 a.a.
NCBI ID   WP_012961663.1    Uniprot ID   A0AA36JX46
Organism   Streptococcus gallolyticus UCN34     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 678703..689368
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GALLO_RS03585 (GALLO_0655) - 680110..681690 (+) 1581 WP_012961659.1 DEAD/DEAH box helicase -
  GALLO_RS03590 (GALLO_0656) - 681734..682018 (-) 285 WP_012961660.1 GIY-YIG nuclease family protein -
  GALLO_RS03595 (GALLO_0657) - 681981..682754 (-) 774 WP_012961661.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  GALLO_RS03600 (GALLO_0658) - 682862..683608 (+) 747 WP_012961662.1 lysophospholipid acyltransferase family protein -
  GALLO_RS03605 (GALLO_0659) comEA 683703..684368 (+) 666 WP_012961663.1 helix-hairpin-helix domain-containing protein Machinery gene
  GALLO_RS03610 (GALLO_0660) comEC/celB 684361..686592 (+) 2232 WP_012961664.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  GALLO_RS03615 (GALLO_0661) holA 686666..687703 (+) 1038 WP_012961665.1 DNA polymerase III subunit delta -
  GALLO_RS03620 (GALLO_0662) sodA 687792..688400 (+) 609 WP_012961666.1 superoxide dismutase SodA -
  GALLO_RS03625 (GALLO_0663) - 688552..689277 (+) 726 WP_012961667.1 YebC/PmpR family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23423.11 Da        Isoelectric Point: 4.3235

>NTDB_id=36188 GALLO_RS03605 WP_012961663.1 683703..684368(+) (comEA) [Streptococcus gallolyticus UCN34]
MIEEIKEKLLENKTLVAVLGTILVMLIGFFAWSNVTKTTADAQSDLPALSTTFSASSSASDLKTERSSSQTETQKVFVDI
KGAVKNEGVYELSSGSRVTDVVKLAGGFTEDADKKSVNLAEKVTDESMIYVAKVGENVAPATTNSQANGSAQQEESSDKI
NLNTATLAELQTISGIGAKRAQDIIDYRDANGGFSSVDDLANVSGIGEKTLEKLKSEVTVD

Nucleotide


Download         Length: 666 bp        

>NTDB_id=36188 GALLO_RS03605 WP_012961663.1 683703..684368(+) (comEA) [Streptococcus gallolyticus UCN34]
ATGATTGAAGAAATAAAAGAAAAACTTTTGGAGAACAAAACGTTGGTAGCAGTGTTGGGAACAATACTTGTCATGTTAAT
CGGATTTTTTGCTTGGTCAAATGTGACAAAAACAACAGCGGATGCGCAAAGTGACCTACCTGCCCTAAGCACGACTTTTT
CGGCAAGTAGCAGCGCAAGTGATTTAAAAACAGAACGTTCAAGTTCGCAAACTGAAACTCAAAAAGTGTTTGTAGATATC
AAAGGCGCTGTGAAAAATGAGGGTGTTTATGAGCTTTCAAGCGGTAGCCGTGTGACAGATGTGGTCAAATTAGCAGGTGG
TTTTACAGAAGATGCTGATAAGAAGTCGGTGAATTTGGCTGAAAAAGTAACCGATGAATCGATGATTTATGTGGCAAAAG
TTGGTGAAAATGTTGCTCCTGCAACGACTAATTCACAAGCAAATGGCAGCGCTCAACAGGAAGAAAGTTCAGATAAAATC
AATCTTAATACCGCAACTTTGGCGGAACTCCAGACGATTTCTGGCATTGGCGCCAAACGTGCCCAAGACATTATTGACTA
CCGTGATGCCAATGGTGGTTTTTCATCAGTTGATGACTTGGCGAATGTGTCTGGTATCGGAGAAAAAACACTAGAAAAGC
TAAAATCTGAGGTGACCGTTGATTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(157-219)

SLBB domain (SLBB)

(78-131)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Streptococcus thermophilus LMD-9

47.639

100

0.502
  comEA/celA/cilE Streptococcus mitis SK321

47.059

100

0.471
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

46.154

100

0.462
  comEA/celA/cilE Streptococcus pneumoniae Rx1

44.843

100

0.452
  comEA/celA/cilE Streptococcus pneumoniae D39

44.843

100

0.452
  comEA/celA/cilE Streptococcus pneumoniae R6

44.843

100

0.452
  comEA/celA/cilE Streptococcus mitis NCTC 12261

44.796

100

0.448
  comEA Latilactobacillus sakei subsp. sakei 23K

38.565

100

0.389
  comEA Staphylococcus aureus MW2

36.818

99.548

0.367

Multiple sequence alignment