Detailed information NTG0036189

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: GALLO_RS03610
• Genome accession: NC_013798
• Coordinates: 684361..686592 (+)
• Length: 743 a.a.
• NCBI ID: WP_012961664.1
• Uniprot ID: A0AA36JXM6
• Organism: Streptococcus gallolyticus UCN34
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 679361..691592

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GALLO_RS03585 (GALLO_0655)	-	680110..681690 (+)	1581	WP_012961659.1	DEAD/DEAH box helicase	-
GALLO_RS03590 (GALLO_0656)	-	681734..682018 (-)	285	WP_012961660.1	GIY-YIG nuclease family protein	-
GALLO_RS03595 (GALLO_0657)	-	681981..682754 (-)	774	WP_012961661.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
GALLO_RS03600 (GALLO_0658)	-	682862..683608 (+)	747	WP_012961662.1	lysophospholipid acyltransferase family protein	-
GALLO_RS03605 (GALLO_0659)	comEA	683703..684368 (+)	666	WP_012961663.1	helix-hairpin-helix domain-containing protein	Machinery gene
GALLO_RS03610 (GALLO_0660)	comEC/celB	684361..686592 (+)	2232	WP_012961664.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
GALLO_RS03615 (GALLO_0661)	holA	686666..687703 (+)	1038	WP_012961665.1	DNA polymerase III subunit delta	-
GALLO_RS03620 (GALLO_0662)	sodA	687792..688400 (+)	609	WP_012961666.1	superoxide dismutase SodA	-
GALLO_RS03625 (GALLO_0663)	-	688552..689277 (+)	726	WP_012961667.1	YebC/PmpR family DNA-binding transcriptional regulator	-
GALLO_RS03630 (GALLO_0664)	queA	689309..690337 (-)	1029	WP_009853772.1	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	-
GALLO_RS03635 (GALLO_0665)	-	690513..691013 (+)	501	WP_012961668.1	VIT1/CCC1 transporter family protein	-

Sequence

Protein

• Length: 743 a.a.
• Molecular weight: 83804.23 Da
• Isoelectric Point: 8.6237

>NTDB_id=36189 GALLO_RS03610 WP_012961664.1 684361..686592(+) (comEC/celB) [Streptococcus gallolyticus UCN34]
MIKYFPIKPIQLAFLLILLYYFCFSKVIGCLMFLLLALVFLWQQYGWKAWCQVCLCLTCFAVFFLTKSNQTEQAYQAAPA
HLTKIQMIPDTISVNGDLLSFRGKEAGRTYQIFYTLKSEKEQHFFKTLNQTIVLSGDMDLEEATPQRNFGGFDYRTYLKH
EGIYRVVNLSAINNVELVYKMTLWEKLHDVRRKAIVSIQRHFPAPMQHYMTGLLFGYLDKSFDEMSDVYTSLGIIHLFAL
SGMQVGFFVGAFRFFFLRLGLRRDYVDILQIPFSLVYAGLTGFSVSVIRSLIQSAFANLGIKKLDNLALTLFVLFIVMPN
FLLTTGGILSFTYAFILSFINFDDISRYQKIIAESLTISLASLPLLIHFFAVFQPLSVLLTAIFSVAFDTIMLPMLSLIF
ILSLLVKLTCFNGCFVFLETVIKNTKAILGGPIVFGKPSLGILVLLFLTLGVLYDCWRRKKMAIFLVSLVGLLFFQIKHP
LENEVTVVDIGQGDSIFVRDVKGHTLLIDVGGKVSFSEKNAWQERLTDSNAERTLIPYLNSRGVGKIDQLVLTHTDTDHM
GDMLEVAKQVKIGEILVSQGSLTKPDFVAKLQAMKTKVRVVTAGDVLPIMGGHLQVLYPSQTGDGGNNDSVVLYGNLLGK
NFLFTGDLEEEGEQELIATYPNLPVDVLKAGHHGSKGSSSSEFLAHISPQIALISAGQNNRYKHPHQETLERFRAQNMTI
YRTDEQGAIRFRGLNHWKIETVR

Nucleotide

• Length: 2232 bp

>NTDB_id=36189 GALLO_RS03610 WP_012961664.1 684361..686592(+) (comEC/celB) [Streptococcus gallolyticus UCN34]
TTGATTAAATATTTTCCCATTAAGCCAATTCAATTGGCTTTTTTGCTCATTTTGCTCTATTATTTTTGCTTTTCAAAAGT
GATTGGGTGTTTGATGTTTCTCTTGCTAGCCTTGGTGTTTTTATGGCAACAGTATGGTTGGAAGGCTTGGTGTCAAGTTT
GCTTGTGTTTAACCTGTTTTGCGGTATTTTTTCTGACTAAGTCTAATCAGACAGAGCAGGCTTATCAAGCAGCACCAGCT
CATTTAACAAAAATCCAGATGATTCCTGACACGATTTCGGTCAATGGGGATTTGCTGTCCTTTCGAGGTAAGGAAGCTGG
GCGGACTTATCAGATTTTTTATACCTTGAAATCGGAGAAAGAACAGCATTTTTTTAAGACATTAAATCAAACGATTGTTT
TATCTGGTGATATGGACTTGGAAGAAGCAACGCCCCAGCGGAATTTTGGTGGTTTTGATTATCGTACTTACCTTAAACAT
GAAGGCATTTATCGTGTGGTAAATTTGTCGGCGATTAACAATGTTGAACTTGTTTATAAGATGACTTTGTGGGAGAAGCT
ACATGATGTTCGACGAAAGGCTATTGTTAGTATTCAGCGGCATTTTCCTGCTCCTATGCAACATTATATGACTGGGCTTT
TGTTTGGCTATCTGGATAAATCGTTTGATGAGATGAGTGATGTTTACACGAGTTTAGGAATTATTCACCTCTTTGCTCTT
TCAGGCATGCAGGTCGGCTTTTTTGTGGGGGCATTCCGCTTTTTCTTTCTACGTCTTGGGTTACGCCGAGATTATGTGGA
CATACTACAAATCCCATTTTCACTTGTCTATGCGGGGCTGACTGGCTTTTCCGTTTCGGTGATTCGGAGTTTAATTCAAT
CTGCTTTTGCAAATCTTGGTATTAAAAAATTAGATAACTTGGCTTTAACTTTGTTTGTTCTTTTCATAGTTATGCCAAAT
TTTCTGCTGACGACGGGAGGCATTCTTTCGTTTACTTACGCTTTTATTCTCAGTTTTATTAACTTTGATGACATTAGTCG
CTATCAGAAAATCATTGCGGAAAGTTTGACGATTTCATTAGCCAGTTTGCCCTTGTTAATTCATTTTTTTGCTGTGTTTC
AACCGTTATCTGTCTTATTGACAGCAATTTTTTCTGTGGCATTTGACACTATTATGTTGCCAATGCTATCACTCATTTTT
ATTTTATCGCTCTTGGTTAAACTGACTTGTTTTAATGGTTGTTTTGTTTTCTTGGAAACTGTTATCAAGAACACTAAGGC
AATTTTAGGCGGTCCGATTGTGTTTGGTAAACCAAGTCTTGGTATCTTGGTGCTACTATTTTTAACATTAGGCGTGCTTT
ATGATTGCTGGCGACGAAAGAAAATGGCAATTTTTCTTGTCAGCTTAGTAGGTCTGCTATTTTTTCAAATCAAGCATCCG
CTAGAAAACGAGGTGACGGTGGTTGATATTGGGCAGGGAGATAGTATTTTTGTGCGTGATGTTAAGGGGCATACGCTGCT
AATTGATGTGGGCGGAAAGGTGAGTTTTAGTGAGAAGAACGCGTGGCAGGAACGGCTGACGGATAGCAATGCGGAGCGAA
CGTTGATTCCTTATCTCAACAGTCGCGGCGTTGGAAAAATTGACCAGTTAGTTCTGACGCACACGGATACTGACCACATG
GGAGATATGCTGGAAGTGGCAAAGCAGGTGAAAATTGGTGAAATTCTGGTTAGTCAGGGAAGTTTGACAAAGCCAGATTT
TGTGGCGAAATTACAAGCCATGAAAACCAAGGTGCGCGTGGTAACAGCTGGTGATGTTTTGCCGATTATGGGAGGTCACC
TGCAAGTGCTTTATCCGAGCCAGACTGGTGATGGCGGTAACAATGACTCGGTGGTGCTTTATGGGAATCTTTTGGGTAAG
AATTTCTTATTTACAGGAGATTTGGAAGAAGAAGGCGAGCAAGAGTTGATAGCAACTTATCCCAATCTGCCGGTTGATGT
CTTAAAAGCAGGACATCATGGCTCAAAAGGGTCATCAAGCTCAGAATTTCTCGCTCACATTTCACCGCAAATTGCTTTGA
TTTCCGCAGGGCAAAATAACCGCTACAAACATCCTCATCAAGAAACGCTTGAACGCTTCCGAGCACAAAACATGACCATT
TACCGTACAGACGAACAAGGCGCTATCCGCTTTAGAGGATTAAACCACTGGAAAATCGAAACAGTGAGGTAG

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (491-697)

• Competence protein (Competence) (213-459)

• Domain of unknown function (DUF4131) (DUF4131) (27-174)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	52.561	99.865	0.525
comEC/celB	Streptococcus mitis SK321	52.156	99.865	0.521
comEC/celB	Streptococcus pneumoniae TIGR4	51.009	100	0.51
comEC/celB	Streptococcus pneumoniae Rx1	50.471	100	0.505
comEC/celB	Streptococcus pneumoniae D39	50.471	100	0.505
comEC/celB	Streptococcus pneumoniae R6	50.471	100	0.505
comEC	Lactococcus lactis subsp. cremoris KW2	47.645	100	0.476