Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   E8M06_RS00400 Genome accession   NZ_CP039462
Coordinates   69227..70408 (+) Length   393 a.a.
NCBI ID   WP_136581005.1    Uniprot ID   -
Organism   Streptococcus suis strain WUSS351     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 64227..75408
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E8M06_RS00380 (E8M06_00380) mutL 65619..67556 (+) 1938 WP_014637283.1 DNA mismatch repair endonuclease MutL -
  E8M06_RS00385 (E8M06_00385) ruvA 67595..68185 (+) 591 WP_136581002.1 Holliday junction branch migration protein RuvA -
  E8M06_RS00395 (E8M06_00395) - 68621..69190 (+) 570 WP_136581004.1 DNA-3-methyladenine glycosylase I -
  E8M06_RS00400 (E8M06_00400) cinA 69227..70408 (+) 1182 WP_136581005.1 competence/damage-inducible protein A Machinery gene
  E8M06_RS00405 (E8M06_00405) recA 70460..71611 (+) 1152 WP_029752404.1 recombinase RecA Machinery gene
  E8M06_RS00410 (E8M06_00410) spx 71847..72245 (+) 399 WP_105184188.1 transcriptional regulator Spx -
  E8M06_RS00415 (E8M06_00415) - 72345..72611 (+) 267 WP_002939360.1 IreB family regulatory phosphoprotein -
  E8M06_RS00420 (E8M06_00420) ruvX 72611..73030 (+) 420 WP_002939356.1 Holliday junction resolvase RuvX -
  E8M06_RS00425 (E8M06_00425) - 73042..73362 (+) 321 WP_002939343.1 DUF1292 domain-containing protein -
  E8M06_RS11465 - 73619..73741 (+) 123 WP_261291941.1 hypothetical protein -
  E8M06_RS00430 (E8M06_00430) rpsJ 73951..74259 (+) 309 WP_014735259.1 30S ribosomal protein S10 -
  E8M06_RS00435 (E8M06_00435) rplC 74357..74983 (+) 627 WP_011921686.1 50S ribosomal protein L3 -

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 42856.76 Da        Isoelectric Point: 4.3529

>NTDB_id=358822 E8M06_RS00400 WP_136581005.1 69227..70408(+) (cinA) [Streptococcus suis strain WUSS351]
MKAELIAVGTEILTGQIINTNAQFLSEKCAELGVDVYFHTAVGDNENRLLSVLEVASQRSDLVILCGGLGPTEDDLTKQT
LATFLGRNLVFDELAMAKLDRFFTSRPGRVRTPNNERQAQIVEGSQALQNLAGLAVGGMVEQDGVTYIVLPGPPSELKAM
FSESLLPLLSQSQQQLYSRVLRFFGIGESQLVTVLADLIDKQTDPTLAPYAKVGEVTLRLSTKATSQEEANLRLNQLEEE
ILQHDKLADYFYAYGEDNSLVKTVATGLVEKKQTIAIVEQGTGGLLQAELSLALADQPYFSGGKVIGQLGTGLGWLSEDA
DRIRQELQADLGLAVSVLIKPESTEDNVLAKVYLTLATPSGISQKEIDLGGYSWQYLRQLACLQAWDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=358822 E8M06_RS00400 WP_136581005.1 69227..70408(+) (cinA) [Streptococcus suis strain WUSS351]
ATGAAAGCAGAACTAATCGCCGTTGGGACGGAGATTTTGACAGGTCAAATCATTAATACCAATGCTCAGTTCCTTTCGGA
GAAATGTGCAGAGCTGGGAGTTGATGTTTATTTCCACACAGCTGTTGGAGATAATGAAAACAGGCTTCTGTCTGTACTGG
AAGTAGCCAGTCAGCGGAGCGACTTGGTCATTCTCTGTGGAGGACTTGGTCCAACTGAGGATGACTTGACCAAGCAGACC
TTGGCGACCTTCTTAGGTAGAAATCTTGTGTTTGATGAGTTGGCTATGGCAAAATTAGACCGTTTCTTTACCAGTCGCCC
AGGTCGTGTCCGTACACCAAATAATGAACGTCAGGCACAGATTGTGGAGGGAAGTCAGGCGCTACAGAATCTAGCTGGTT
TAGCTGTTGGTGGTATGGTTGAGCAAGATGGTGTAACCTATATTGTTTTGCCTGGCCCACCAAGTGAGCTCAAGGCCATG
TTTTCTGAGAGTCTCTTACCTTTACTGTCCCAATCTCAGCAGCAACTTTATTCGCGTGTCCTACGCTTTTTTGGCATTGG
CGAAAGCCAGTTGGTGACTGTTTTGGCGGACTTGATTGACAAGCAGACAGACCCAACTCTTGCTCCTTATGCAAAAGTTG
GAGAGGTGACTTTACGCTTGTCCACCAAAGCGACCAGCCAAGAAGAAGCAAATCTACGTTTAAATCAGTTGGAAGAGGAA
ATCTTACAACATGACAAACTGGCAGACTATTTCTATGCCTACGGAGAGGACAATAGTTTGGTCAAAACGGTAGCGACTGG
TTTGGTTGAGAAAAAACAAACCATAGCCATTGTCGAGCAGGGGACAGGAGGGCTCTTGCAGGCAGAATTGAGTTTGGCTT
TGGCTGATCAGCCTTATTTTAGCGGAGGAAAAGTCATCGGTCAGTTAGGGACAGGATTGGGCTGGCTATCAGAAGATGCA
GATCGCATTCGACAGGAGCTGCAAGCTGATTTAGGTTTGGCTGTGTCTGTGCTTATCAAACCGGAATCAACAGAGGACAA
CGTACTTGCAAAAGTATACCTCACTTTGGCTACGCCCTCGGGTATTTCCCAAAAAGAGATAGATTTAGGTGGTTATTCGT
GGCAATACCTTCGCCAGCTTGCTTGTCTGCAGGCCTGGGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

94.656

100

0.947
  cinA Streptococcus pneumoniae TIGR4

56.49

100

0.598
  cinA Streptococcus pneumoniae R6

56.01

100

0.593
  cinA Streptococcus mitis SK321

56.01

100

0.593
  cinA Streptococcus pneumoniae Rx1

56.01

100

0.593
  cinA Streptococcus mutans UA159

56.448

100

0.59
  cinA Streptococcus mitis NCTC 12261

55.769

100

0.59
  cinA Streptococcus pneumoniae D39

55.769

100

0.59
  cinA Bacillus subtilis subsp. subtilis str. 168

48.534

78.117

0.379

Multiple sequence alignment