Detailed information NTG0354864

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: GPX93_RS08455
• Genome accession: NZ_CP046749
• Coordinates: 1880094..1881374 (-)
• Length: 426 a.a.
• NCBI ID: WP_000130332.1
• Uniprot ID: A0AAU8WEE3
• Organism: Vibrio cholerae strain 2015V-1118
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1875094..1886374

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GPX93_RS08440	ppiD	1875143..1877002 (-)	1860	WP_071187141.1	peptidylprolyl isomerase	-
GPX93_RS08445	-	1877155..1877427 (-)	273	WP_001044516.1	HU family DNA-binding protein	-
GPX93_RS08450	lon	1877611..1879971 (-)	2361	WP_123162828.1	endopeptidase La	-
GPX93_RS08455	clpX	1880094..1881374 (-)	1281	WP_000130332.1	ATP-dependent protease ATP-binding subunit ClpX	Regulator
GPX93_RS08460	clpP	1881454..1882080 (-)	627	WP_000121678.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
GPX93_RS08465	tig	1882186..1883487 (-)	1302	WP_123162829.1	trigger factor	-
GPX93_RS18695	-	1883778..1883996 (-)	219	WP_001881672.1	hypothetical protein	-
GPX93_RS08475	-	1883986..1885779 (+)	1794	WP_001891957.1	sensor histidine kinase	-

Sequence

Protein

• Length: 426 a.a.
• Molecular weight: 46490.23 Da
• Isoelectric Point: 4.7780

>NTDB_id=354864 GPX93_RS08455 WP_000130332.1 1880094..1881374(-) (clpX) [Vibrio cholerae strain 2015V-1118]
MTDKSKEGGSSKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKDVLPKKESAALPTPRKIREHLDDYVI
GQEHAKKVLAVAVYNHYKRLRNGDTTSEGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDV
ENIIQKLLQKCDYDVAKAERGIVYIDEIDKISRKSENPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQV
DTSKILFICGGAFAGLDKVIEQRVATGTGIGFGADVRSKDNSKTLSELFTQVEPEDLVKYGLIPEFIGRLPVTATLTELD
EAALIQILCEPKNALTKQYAALFELENVDLEFREDALKAIAAKAMKRKTGARGLRSILEAVLLETMYELPSMEEVSKVVI
DESVINGESAPLLIYSANESQAAGAE

Nucleotide

• Length: 1281 bp

>NTDB_id=354864 GPX93_RS08455 WP_000130332.1 1880094..1881374(-) (clpX) [Vibrio cholerae strain 2015V-1118]
ATGACAGACAAAAGCAAAGAGGGCGGTAGTAGTAAACTGCTGTACTGCTCTTTCTGTGGCAAAAGCCAGCACGAAGTTCG
CAAACTGATCGCAGGTCCGTCCGTGTATATTTGTGATGAGTGCGTTGATTTATGCAACGACATCATCCGCGAAGAGATCA
AAGATGTTCTGCCAAAAAAGGAATCAGCGGCGTTGCCGACGCCAAGAAAGATTCGTGAACATCTCGACGATTATGTGATT
GGTCAAGAACACGCCAAAAAAGTGCTAGCCGTTGCGGTATATAACCACTACAAGCGTTTACGTAATGGTGATACGACTAG
CGAAGGCGTTGAGCTGGGCAAGAGTAACATTTTGCTGATTGGCCCAACGGGTAGCGGTAAAACACTACTGGCTGAAACGC
TGGCGCGTTTGCTGGATGTGCCATTTACCATGGCGGATGCGACCACATTAACCGAAGCGGGTTATGTGGGCGAAGATGTA
GAAAATATCATTCAAAAGCTGCTGCAAAAATGCGATTACGATGTTGCAAAAGCGGAGCGTGGTATCGTCTACATCGATGA
AATTGACAAAATTTCTCGTAAGTCTGAAAACCCATCCATCACACGTGACGTGTCGGGTGAAGGGGTTCAGCAAGCGCTGT
TAAAACTGATTGAAGGTACAGTTGCTTCGGTTCCACCACAAGGTGGCCGTAAACATCCTCAGCAGGAATTCCTGCAAGTC
GACACCTCAAAAATCCTATTTATCTGTGGTGGCGCGTTTGCTGGCCTAGATAAAGTGATTGAACAGCGTGTTGCGACAGG
GACTGGTATTGGTTTTGGCGCGGATGTGCGTTCTAAAGACAACAGCAAAACCTTGAGCGAACTGTTTACTCAGGTTGAAC
CTGAAGATTTGGTGAAATACGGTTTGATCCCAGAGTTCATTGGTCGTCTGCCTGTGACGGCAACGCTGACTGAACTGGAT
GAAGCAGCATTGATTCAAATTCTGTGTGAACCAAAGAATGCATTGACCAAACAGTATGCGGCGTTGTTTGAACTGGAAAA
CGTTGATCTGGAGTTTCGTGAAGATGCGCTGAAAGCGATTGCCGCTAAAGCGATGAAGCGTAAAACCGGTGCGCGTGGTC
TACGTTCAATCCTTGAAGCAGTTCTACTGGAAACCATGTATGAACTGCCTTCAATGGAAGAGGTCAGCAAGGTGGTGATT
GACGAATCTGTGATCAACGGAGAGTCCGCACCGCTACTGATTTACAGCGCTAATGAGAGCCAAGCCGCTGGTGCGGAGTA
A

Domains

Predicted by InterProScan.

• ClpX C4-type zinc finger (zf-C4_ClpX) (14-51)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (319-396)

• AAA domain (Cdc48 subfamily) (AAA_2) (114-312)

3D structure

• AlphaFold DB: A0AAU8WEE3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	58.706	94.366	0.554
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	53.333	95.07	0.507