Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/comE2   Type   Regulator
Locus tag   GE024_RS04700 Genome accession   NZ_CP046521
Coordinates   917128..917877 (+) Length   249 a.a.
NCBI ID   WP_001021687.1    Uniprot ID   -
Organism   Streptococcus canis strain HL_100     
Function   activate transcription of early competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 912128..922877
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE024_RS04675 (GE024_04670) - 912704..912976 (+) 273 WP_025193630.1 DUF3884 family protein -
  GE024_RS04680 (GE024_04675) - 913065..913256 (+) 192 WP_000192881.1 hypothetical protein -
  GE024_RS04685 (GE024_04680) comA 913458..915608 (+) 2151 WP_093998659.1 peptide cleavage/export ABC transporter Regulator
  GE024_RS04690 (GE024_04685) - 915630..915785 (+) 156 WP_000794567.1 hypothetical protein -
  GE024_RS04695 (GE024_04690) - 916244..917113 (+) 870 WP_000642951.1 GHKL domain-containing protein -
  GE024_RS04700 (GE024_04695) comE/comE2 917128..917877 (+) 750 WP_001021687.1 LytTR family DNA-binding domain-containing protein Regulator
  GE024_RS04705 (GE024_04700) - 918413..919048 (+) 636 WP_000222717.1 hypothetical protein -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29377.93 Da        Isoelectric Point: 8.1162

>NTDB_id=352587 GE024_RS04700 WP_001021687.1 917128..917877(+) (comE/comE2) [Streptococcus canis strain HL_100]
MNIIVLDDNIHHQLRLESALYYVARSLHIHINIECARTIQALREYMNQEEVNQIYFLDLEIGNQKNLGFEIAKEIRNNNP
YAVIIFVTSYSDLMPLVFQYHLSALDFIIKDLKETEFRNRLKQCLEQVIISFKKKSDGELLRYSYQNRTGICIPFSDILF
IQTSVKPHRLIIYTVNFIKEFYGTLNDILDLDSKNYFEKVDRSTIINVDNVTEYSSKTREVKFFEGTTCLVSRLRIKDVK
TRLRNKGII

Nucleotide


Download         Length: 750 bp        

>NTDB_id=352587 GE024_RS04700 WP_001021687.1 917128..917877(+) (comE/comE2) [Streptococcus canis strain HL_100]
ATGAATATTATTGTTCTGGATGACAATATTCATCATCAGTTGCGACTAGAGTCTGCTCTTTATTATGTAGCTCGGTCTTT
ACATATTCATATCAATATTGAATGTGCTAGAACAATACAGGCATTAAGAGAGTATATGAATCAAGAAGAAGTAAATCAGA
TATATTTTCTAGATTTAGAAATTGGCAATCAAAAAAATTTAGGTTTTGAGATTGCTAAAGAAATAAGAAATAATAATCCT
TATGCAGTTATTATATTTGTGACTTCATATTCCGACTTGATGCCCCTAGTATTTCAATATCATCTTTCGGCATTAGATTT
TATTATTAAAGATCTTAAAGAAACAGAATTTCGTAATCGGTTAAAGCAGTGTTTGGAACAAGTAATAATTTCATTTAAGA
AAAAATCTGATGGGGAATTGTTAAGATATAGTTACCAGAACAGAACTGGTATCTGCATACCTTTTTCCGATATACTTTTT
ATTCAAACCTCAGTTAAACCGCATCGATTAATTATTTATACAGTAAATTTTATTAAAGAATTTTATGGTACTTTGAATGA
TATTCTAGATTTAGATAGTAAGAATTATTTTGAAAAAGTAGATCGTTCAACAATAATAAATGTGGATAATGTTACTGAGT
ACAGTTCGAAAACAAGAGAAGTAAAATTTTTTGAAGGAACAACATGTCTTGTATCTAGATTGAGAATTAAGGATGTAAAA
ACTAGATTAAGAAATAAAGGAATAATATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(152-243)

Response regulator receiver domain (Response_reg)

(4-121)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/comE2 Streptococcus gordonii strain NCTC7865

38.153

100

0.382
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

38.153

100

0.382
  comE Streptococcus mitis SK321

37.008

100

0.378
  comE Streptococcus pneumoniae Rx1

37.008

100

0.378
  comE Streptococcus pneumoniae D39

37.008

100

0.378
  comE Streptococcus pneumoniae R6

37.008

100

0.378
  comE Streptococcus pneumoniae TIGR4

37.008

100

0.378
  comE Streptococcus mitis NCTC 12261

37.008

100

0.378
  comE Streptococcus infantis strain Atu-4

36.948

100

0.369

Multiple sequence alignment